AA-5-HT
- CAS No.
- 187947-37-1
- Chemical Name:
- AA-5-HT
- Synonyms
- AA-5-HT;ARACHIDONYLSEROTONIN;ARACHIDONOYL SEROTONIN;N-Arachidonoylserotonin;N-ARACHIDONYL-5-HYDROXYTRYPTAMINE;Arachidonoylserotonin >=98% (HPLC), oil;N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide;N-[2-(5-HYDROXY-1H-INDOL-3-YL)ETHYL]-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;(5Z,8Z,11Z,14Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]icosa-5,8,11,14-tetraenamide;N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenamide
- CBNumber:
- CB7754434
- Molecular Formula:
- C30H42N2O2
- Molecular Weight:
- 462.67
- MDL Number:
- MFCD02179189
- MOL File:
- 187947-37-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Arachidonoylserotonin ≥98% (HPLC), oil | A7357 | 25mg | $503 |
| Arachidonoyl Serotonin ≥98% | 70665 | 5mg | $49 |
| Arachidonoyl Serotonin ≥98% | 70665 | 10mg | $82 |
| Arachidonoyl Serotonin ≥98% | 70665 | 100mg | $570 |
| Arachidonoyl Serotonin ≥98% | 70665 | 50mg | $310 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H336 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
AA-5-HT price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A7357 | Arachidonoylserotonin ≥98% (HPLC), oil | 187947-37-1 | 25mg | $503 | 2023-01-07 | Buy |
| Cayman Chemical | 70665 | Arachidonoyl Serotonin ≥98% | 187947-37-1 | 5mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 70665 | Arachidonoyl Serotonin ≥98% | 187947-37-1 | 10mg | $82 | 2024-03-01 | Buy |
| Cayman Chemical | 70665 | Arachidonoyl Serotonin ≥98% | 187947-37-1 | 100mg | $570 | 2024-03-01 | Buy |
| Cayman Chemical | 70665 | Arachidonoyl Serotonin ≥98% | 187947-37-1 | 50mg | $310 | 2024-03-01 | Buy |
AA-5-HT Chemical Properties,Uses,Production
Uses
N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 μM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1].
Definition
ChEBI: N-arachidonoylserotonin is an N-acylserotonin obtained by formal condensation of the carboxy group of arachidonic acid with the primary amino group of serotonin. It has a role as a human metabolite, a signalling molecule, an antioxidant, an anti-inflammatory agent, an anticonvulsant, a capsaicin receptor antagonist and an EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor. It is a member of phenols and a N-acylserotonin. It is functionally related to an arachidonic acid.
Biological Activity
Dual fatty acid amide hydrolase (FAAH) inhibitor/TRPV1 antagonist (IC 50 values are 5.6 μ M and 37-40 nM for FAAH and TRPV1 respectively). Inactive at cPLA 2 , CB 1 or 5-HT receptors. Displays strong analgesic activity against both acute and chronic peripheral pain.
References
[1] Ortar G, et al. New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. J Med Chem. 2007;50(26):6554-6569. DOI:10.1021/jm070678q
AA-5-HT Preparation Products And Raw materials
Raw materials
Preparation Products
AA-5-HT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Hebei Shengyuan Jinlong Import and Export Co. LTD | +8617367750398 | info@hebeisyjl.com | China | 1838 | 58 |
| DONBOO AMINO ACID COMPANY | +8618051385538 | donboo@donboo.com | China | 9363 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| HangZhou YuHao Chemical Technology Co., Ltd. | 0571-82693216 | info@yuhaochemical.com | China | 2028 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3069 | 58 |
View Lastest Price from AA-5-HT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-05 | Arachidonyl serotonin
187947-37-1
|
US $178.00-1120.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2023-06-26 | Arachidonoyl serotonin
187947-37-1
|
US $150.00 / ASSAYS | 10g | >99% | 500kg/month | Hebei Mingeng Biotechnology Co., Ltd |
-
- Arachidonyl serotonin
187947-37-1
- US $178.00-1120.00 / mg
- TargetMol Chemicals Inc.
-
- Arachidonoyl serotonin
187947-37-1
- US $150.00 / ASSAYS
- >99%
- Hebei Mingeng Biotechnology Co., Ltd
