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2-Methyl butyric acid

2-Methyl butyric acid Structure
2-Methyl butyric acid structure
CAS No.
116-53-0
Chemical Name:
2-Methyl butyric acid
Synonyms
2-METHYLBUTANOIC ACID;2-METHYLBUTYRIC ACID;Ethylmethylacetic acid;2-methylbutyrate;DL-2-Methylbutyric acid;2-methylbutyric;METHYLETHYL ACETIC ACID;NSC 7304;FEMA 2695;2-Methylbutyri
CBNumber:
CB7766118
Molecular Formula:
C5H10O2
Molecular Weight:
102.13
MDL Number:
MFCD00002669
MOL File:
116-53-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:34:25
Product description Number Pack Size Price
(±)-2-Methylbutyric acid natural, ≥98%, FG W269514 1 each $62.3
(±)-2-Methylbutyric acid natural,≥98%,FG W269514 100g $93.4
(±)-2-Methylbutyric acid natural,≥98%,FG W269514 1kg $364
(±)-2-Methylbutyric acid natural,≥98%,FG W269514 5kg $1170
2-Methylbutyric acid ≥98%, FG W269506 1 each $58
More product size
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2-Methyl butyric acid Properties

Melting point -70 °C
Boiling point 176-177 °C (lit.)
Density 0.936 g/mL at 25 °C (lit.)
vapor pressure 0.5 mm Hg ( 20 °C)
refractive index n20/D 1.405(lit.)
FEMA 2695 | 2-METHYLBUTYRIC ACID
FLAVIS Number 08.046 | 2-Methylbutyric acid
Flash point 165 °F
storage temp. Sealed in dry,Room Temperature
solubility 20g/l
form Liquid
pka 4.8(at 25℃)
color Clear colorless to pale yellow
Odor at 10.00 % in propylene glycol. pungent acid roquefort cheese
Odor Type acidic
biological source synthetic
explosive limit 1.6-7.3%(V)
Water Solubility 45 g/L (20 ºC)
JECFA Number 255
BRN 1720486
Henry's Law Constant 6.7×100 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Major Application flavors and fragrances
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C5H10O2/c1-3-4(2)5(6)7/h4H,3H2,1-2H3,(H,6,7)
InChIKey WLAMNBDJUVNPJU-UHFFFAOYSA-N
SMILES CCC(C)C(O)=O
LogP 1.8 at 25℃
Substances Added to Food (formerly EAFUS) 2-METHYLBUTYRIC ACID
FDA 21 CFR 172.515
CAS DataBase Reference 116-53-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII PX7ZNN5GXK
NIST Chemistry Reference Butanoic acid, 2-methyl-(116-53-0)
EPA Substance Registry System 2-Methylbutyric acid (116-53-0)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H290-H302+H312-H314
Precautionary statements  P234-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  21/22-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 3
WGK Germany  1
RTECS  EK7897000
F  13
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29156090
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Oral
Eye Dam. 1
Met. Corr. 1
Skin Corr. 1B
REACH Registrations Active
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 0

2-Methyl butyric acid price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W269514 (±)-2-Methylbutyric acid natural, ≥98%, FG 116-53-0 1 each $62.3 2026-04-30 Buy
Sigma-Aldrich W269514 (±)-2-Methylbutyric acid natural,≥98%,FG 116-53-0 100g $93.4 2026-04-30 Buy
Sigma-Aldrich W269514 (±)-2-Methylbutyric acid natural,≥98%,FG 116-53-0 1kg $364 2026-04-30 Buy
Sigma-Aldrich W269514 (±)-2-Methylbutyric acid natural,≥98%,FG 116-53-0 5kg $1170 2026-04-30 Buy
Sigma-Aldrich W269506 2-Methylbutyric acid ≥98%, FG 116-53-0 1 each $58 2026-04-30 Buy
Product number Packaging Price Buy
W269514 1 each $62.3 Buy
W269514 100g $93.4 Buy
W269514 1kg $364 Buy
W269514 5kg $1170 Buy
W269506 1 each $58 Buy

2-Methyl butyric acid Chemical Properties,Uses,Production

Description

2-methyl butyric acid has a pungent, acrid odor which is similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant fruity taste. It can be prepared either by decarboxylation of methyl ethyl malonic acid or by the oxidation of fermentation amyl alcohol (fusel oil). It is used as a flavor ingredient for butter, cream, cheese flavor deployment. It also provides acyl moiety for the preparation of the respective flavor esters.

References

[1] George A. Burdock, Encyclopedia of Food and Color Additives, Band 1, 1996
[2] T. Tachihara, H. Hashimoto, S. Ishizaki, T. Komai, A. Fujita, M. Ishikawa and T. Kitahara, Microbial resolution of 2-methylbutyric acid and its application to several chiral flavour compounds, Developments in Food Science, 2006, vol. 43, 97-100

Description

2-Methylbutyric acid has a pungent, acrid odor similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant fruity taste. May be prepared by decarboxylation of methyl ethyl malonic acid (with heat); also by oxidation of fermentation amyl alcohol (fusel oil).

Chemical Properties

2-Methylbutyric acid has a pungent, acrid odor similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant, fruity taste. Slightly soluble in water, soluble in alcohol and oils. Also soluble in Propylene glycol and poorly soluble in Glycerin.

Chemical Properties

clear colorless to pale yellowish liquid

Occurrence

Occurring as the d-, l-, and dl-isomers; the racemic form has been reported found in angelica root oil and coffee; the d-isomer in the ester form has been identified in lavender oil. Also reported found in apple, apricot, berries, grapes, papaya, peach, guava, pineapple, potato, bell pepper, tomato, peppermint and spearmint oil, vinegar, wheat breads, cheeses, chicken, mutton, pork, hop oil, beer, cognac, rum, whiskies, cider, cocoa, coffee, tea, peanuts, passion fruit, trassi, mango, plum, tamarind, rice, corn oil, loquat, scallops, Chinese quince, maté, mammee apple and Roman chamomile oil, cranberry, grape brandy, oriental tobacco, and strawberry

Uses

2-Methylbutyric acid, can be used as food additive for butter, cream, cheese flavor deployment. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff. It is also used in the synthesis of 2-methylbutyric anhydride.

Uses

2-Methylbutyric acid was used in the synthesis of 2-methylbutyric anhydride, an acylating agent.

Definition

ChEBI: A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria.

Preparation

By decarboxylation of methyl ethyl malonic acid (with heat); also by oxidation of fermentation amyl alcohol (fusel oil).

Aroma threshold values

Detection: 10 to 60 ppb. Aroma characteristics at 1.0%: acidic sour, pungent, ripe fruit leather, lingonberry, dirty cheesy, fermented pineapple fruity with a woody nuance

Taste threshold values

Taste characteristics at 10 ppm: dirty, acidic sour, ripe fruity, with a dairy buttery and cheesy nuance

General Description

Enantioselective esterification of (+/-)-2-methylbutynic acid catalyzed by Chromobacterium viscosum lipase immobilized in microemulsion-based organogels has been investigated.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Taste at 10 ppm

2-Methyl butyric acid Preparation Products And Raw materials

Raw materials

methylethylmalonic acid FUSEL OIL

Preparation Products

FEMA 3632 Methylbutyric acid Butyl 2-methylbutyrate HEXYL ISOVALERATE STANDARD FOR GC 2-Methylbutyl 2-methylbutyrate
3-Methyl-butyramidine HCl

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2-Methyl butyric acid Suppliers

Global( 494)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5231 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
JINING XINHE CHEMICAL CO., LTD 		+8615318402391 sales@xinhepharma.com China 809 58
Hebei Andu Technology Com.,Ltd 		+86-86-17798073498 +8617798073498 aduchemical@163.com China 296 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Supplier Advantage
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
JINING XINHE CHEMICAL CO., LTD 		58
Hebei Andu Technology Com.,Ltd 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58
career henan chemical co 		58

Related articles

View Lastest Price from 2-Methyl butyric acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methyl butyric acid pictures 2026-05-29 2-Methyl butyric acid
116-53-0
 25kg 98%min 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
2-Methyl butyric acid pictures 2026-05-28 2-Methyl butyric acid
116-53-0
 $20.00-50.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2-Methyl butyric acid pictures 2025-06-27 2-Methyl butyric acid
116-53-0
 $10.00-30.00 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

2-Methyl butyric acid Spectrum

2-Methyl butyric acid(116-53-0)MS2-Methyl butyric acid(116-53-0)1HNMR2-Methyl butyric acid(116-53-0)13CNMR2-Methyl butyric acid(116-53-0)IR12-Methyl butyric acid(116-53-0)IR22-Methyl butyric acid(116-53-0)Raman

116-53-0(2-Methyl butyric acid)Related Search:

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METHYLBUTYRIC ACID, DL-2- (+/-)-2-METHYLBUTYRIC ACID 2-METHYLBUTANOIC ACID RARECHEM AL BO 0094 BUTANE-2-CARBOXYLIC ACID FEMA 2695 CARBOXYLIC ACID C5 DL-METHYLETHYLACETIC ACID 2-Methybutyric acid 2-methyl-butanoicaci butanoicacid,2-methyl Butanoicacid,2-methyl- Butanoicacid,2-methyl-,(±)- Butyric acid, 2-methyl- Butyricacid,2-methyl- DL-2-Methylbutanoicacid DL-2-Methylbuttersαure Hydroangelic acid DL-2-Methylbutyric acid,98% DL-2-Methylbutyric acid, 98% 25GR 2-Methylbutyri NSC 7304 NAT.2-METHYL BUTYRIC ACID (2-METHYL BUTYRIC ACID ) 2-methyl butyric acid/DL-2-Methylbutyric acid 116-53-0 2-Methylbuttersαure(±)- 2-methylbutyric 2-methyl-butyricaci 2-Methyl-n-butyricacid Active valeric acid activevalericacid alpha-Methylbutyric acid alpha-methylbutyricacid DL-Ethyl-methylessigsαure DL-α-Methylbutyricacid Ethylmethylacetic acid ethylmethylaceticacid α-Methyl-n-butyricacid METHYL-2-BUTYRIC ACID FCC 2-METHYLBUTYRIC ACID 98+% 2-METHYLBUTYRIC ACID 98+% NATURAL D-2-MethylButyricAcid methylbutyricacid,2-methylbutanoicacid 2-methylbutyric acidiisopropylacetic acid METHYLBUTYRIC ACID, DL-2-(RG) DL-2-Methylbutyric acid 2-METHYLBUTYRIC ACID, NATURAL 2-METHYLBUTYRIC ACID, NATURAL (OPTICALLY ACTIVE) METHYLBUTTERSAEURE, 2- DL-2-MethylbutyricAcid> 2-Methyl butyric acid USP/EP/BP 2-Methyl butyric acid 116-53-0 Phloroglucinol Impurity 128 high qualtiy 2-Methylbutyric Acid (±)-2-Methylbutyric acid DL-Methyl-2 Butyric Acid 2-Methylbutanoic acid (Standard) 2-METHYLBUTYRIC ACID 2-methylbutyrate