Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>L-Alaninamide hydrochloride

L-Alaninamide hydrochloride

L-Alaninamide hydrochloride Structure
L-Alaninamide hydrochloride structure
CAS No.
33208-99-0
Chemical Name:
L-Alaninamide hydrochloride
Synonyms
H-ALA-NH2 HCL;L-ALANAMINE HCL;L-ALANINE AMIDE HYDROCHLORIDE;(2S)-2-AMINOPROPANAMIDE HYDROCHLORIDE;Ala-NH2.Hcl;L-Ala-NH2·HCl;H-L-ALA-NH2 HCL;ALANINE-NH2 HCL;L-ALANILAMIDE HCL;：L-Alaninamide hyd
CBNumber:
CB7766754
Molecular Formula:
C3H9ClN2O
Molecular Weight:
124.57
MDL Number:
MFCD00066145
MOL File:
33208-99-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-12 09:17:10
Product description Number Pack Size Price
L-Alaninamide hydrochloride 95% 459216 1g $28.5
L-Alaninamide hydrochloride 95% 459216 5g $64.8
L-Alaninamide Hydrochloride >97.0%(N) A1919 5g $52
L-Alaninamide Hydrochloride >97.0%(N) A1919 25g $150
L-Alanine amide hydrochloride ≥98%(HPLC) 03010 1G $18.53
More product size
Request For Quotation

L-Alaninamide hydrochloride Properties

Melting point 212-217°C
alpha 11 º (c=1, MeOH)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly), Water
form Solid
color White to Off-White
optical activity [α]25/D +11.0°, c = 1 in methanol
Major Application peptide synthesis
InChI InChI=1S/C3H8N2O.ClH/c1-2(4)3(5)6;/h2H,4H2,1H3,(H2,5,6);1H/t2-;/m0./s1
InChIKey FIAINKIUSZGVGX-DKWTVANSSA-N
SMILES [C@H](N)(C)C(=O)N.Cl
CAS DataBase Reference 33208-99-0(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P280
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  C
Safety Statements  24/25
WGK Germany  3
HS Code  29241990
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
1
1 1

L-Alaninamide hydrochloride price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 459216 L-Alaninamide hydrochloride 95% 33208-99-0 1g $28.5 2026-04-30 Buy
Sigma-Aldrich 459216 L-Alaninamide hydrochloride 95% 33208-99-0 5g $64.8 2026-04-30 Buy
TCI Chemical A1919 L-Alaninamide Hydrochloride >97.0%(N) 33208-99-0 5g $52 2026-04-30 Buy
TCI Chemical A1919 L-Alaninamide Hydrochloride >97.0%(N) 33208-99-0 25g $150 2026-04-30 Buy
Chem-Impex 03010 L-Alanine amide hydrochloride ≥98%(HPLC) 33208-99-0 1G $18.53 2026-05-19 Buy
Product number Packaging Price Buy
459216 1g $28.5 Buy
459216 5g $64.8 Buy
A1919 5g $52 Buy
A1919 25g $150 Buy
03010 1G $18.53 Buy

L-Alaninamide hydrochloride Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

L-Alaninamide hydrochloride is used for preparation of novel amide derivatives of steroidal[3,2-c]pyrazole compounds with glucocorticoid activity.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

L-Alanine methyl ester hydrochloride

2491-20-5

L-Alaninamide hydrochloride

33208-99-0

The general procedure for the synthesis of L-alaninamide hydrochloride from alanine methyl ester hydrochloride is as follows: 500 g of methanol and 100 g of L-alanine were added to a 1000 ml three-necked flask, followed by the slow dropwise addition of 90 ml of thionyl chloride (the reaction temperature was controlled to be below 35 °C). After the dropwise addition, the three-necked flask was transferred to a water bath, heated to reflux temperature (temperature not exceeding 35 °C) and ensured that the generated SO2 was completely removed.Subsequently, the aminolysis reaction was carried out by passing 0.56 kg of ammonia into the reaction system under ice-bath conditions (temperature controlled below 20 °C), after which the reaction mixture was sealed and allowed to stand for 20 h in a room temperature water bath. The temperature of the water bath was raised to 55 °C to remove the remaining ammonia gas, which was finally concentrated to 300 ml and ensured that the ammonia gas was completely removed. Excess ammonium chloride was removed by filtration and the filter cake was washed with 100 ml of methanol, the washings were combined with the mother liquor and transferred to a 1000 ml beaker. The acidification process was completed by slowly adding 34.5 ml of hydrochloric acid at 10% concentration dropwise and adjusting the pH to 1.55. The reaction mixture was sealed and placed in a refrigerator for 12 h. After removal, 400 ml of acetone was added to induce crystallization. The crystals were collected by filtration, washed with an appropriate amount of solvent and subsequently dried at 45 °C for 12 h. 85 g of white crystals were obtained (85% yield). The rotativity of the product was [a] = +11.4°.

References

[1] Journal fur Praktische Chemie - Chemiker - Zeitung, 1996, vol. 338, # 3, p. 251 - 256
[2] Patent: CN108069867, 2018, A. Location in patent: Paragraph 0015-0017

L-Alaninamide hydrochloride Preparation Products And Raw materials

Raw materials

(2R)-2-Aminopropanamide hydrochloride DL-Alanine L-Alanine methyl ester hydrochloride Hydrochloric acid

Preparation Products

L-Alaninamide hydrochloride Suppliers

Global( 467)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 		+8617392709771 1097@dideu.com China 3996 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1006 58
Sichuan HongRi Pharma-Tech Co.,Ltd 		+8618382028708 ni@enlaibio.com China 1100 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		+86-15350851019; +8615350851019 admin@86-ss.com China 999 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13902 58
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		0523-86132544 sales@thbiochem.com CHINA 305 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 		58
Hangzhou ICH Biofarm Co., Ltd 		58
Sichuan HongRi Pharma-Tech Co.,Ltd 		58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55

View Lastest Price from L-Alaninamide hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ALA-NH2.HCL pictures 2026-05-22 ALA-NH2.HCL
33208-99-0
 US $0.00-0.00 / kg 1kg 98+ 1T Sichuan HongRi Pharma-Tech Co.,Ltd
L-Alaninamide hydrochloride pictures 2026-05-22 L-Alaninamide hydrochloride
33208-99-0
 US $999.00-800.00 / kg 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
L-Alaninamide hydrochloride pictures 2026-05-22 L-Alaninamide hydrochloride
33208-99-0
 US $0.00 / Kg/Drum 1KG 98%min 10 tons WUHAN FORTUNA CHEMICAL CO., LTD
  • ALA-NH2.HCL pictures
  • ALA-NH2.HCL
    33208-99-0
  • US $0.00-0.00 / kg
  • 98+
  • Sichuan HongRi Pharma-Tech Co.,Ltd

L-Alaninamide hydrochloride Spectrum

L-Alaninamide hydrochloride(33208-99-0)MSL-Alaninamide hydrochloride(33208-99-0)1HNMRL-Alaninamide hydrochloride(33208-99-0)13CNMRL-Alaninamide hydrochloride(33208-99-0)IR

33208-99-0(L-Alaninamide hydrochloride)Related Search:

Transglutaminase L-Glutamine L-Alanyl-L-Glutamine Topotecan hydrochloride Boc-D-Glutamine
Glycinamide hydrochloride L-Alanine methyl ester hydrochloride H-NVA-NH2 HCL 1-Pyrrolidineaceticacid,alpha-ethylidene-2-oxo-,(alphaZ)-(9CI) 2-aminobutanenitrile
4-Chlorobutyryl chloride 4-CHLORO-BUTYRALDEHYDE H-VAL-NH2 HCL Valeryl chloride H-ALA-PNA HCL
H-Ala-Glu-OH.HCl H-ALA-PHE-OH L-ALANYL-L-TYROSINE

1of4

L-ALANAMINE HCL (L)-ALANINAMIDE HCL L-Ala-NH2·HCl (S)-2-AMINOPROPIONAMIDE HYDROCHLORIDE H-Ala-NH2·HCl (HPLC) L-ALANINAMIDE HYDROCHLORIDE L-ALANINE AMIDE HYDROCHLORIDE ALANINE-NH2 HCL H-L-ALA-NH2 HCL H-ALA-NH2 HCL H-ALA-NH2 HYDROCHLORIDE (2S)-2-AMINOPROPANAMIDE HYDROCHLORIDE L-ALANILAMIDE HCL L-Alanamine Hydrochloride L-AlaninaMide hydrochloride 95% L-alaninamide hydochloride L-Alaninamide hydrochloride ,98% L-Alaninamide hydroc (S)-2-aMinopropanaMide (Hydrochloride) (2S)-2-Aminopropionamide hydrochloride, L-Alaninamide hydrochloride L-AlaninaMide Hydrochloride , 97.0%(N) ：L-Alaninamide hyd Propanamide, 2-amino-,hydrochloride (1:1), (2S)- L-Alaninamide Hydrochloride > aninamide HydrochL Levetiracetam Impurity 38 L-Alaninamide hydrochloride USP/EP/BP L-alanamide hydrochloride [(2S)-1-amino-1-oxopropan-2-yl]azanium L-Alanine amide HCl (S)-alaninamide hydrochloride (S) -2-Amino-propanamide HCl L-Alanine amide·hydrochloride salt Safinamide Impurity 40 L-alaninamide hydrochloride (1:1) L-Alaninamide hydrochloride Safinamide Impurity 34 HCl Ala-NH2.Hcl 33208-99-0 3308-99-0 13208-99-0 133208-99-0 C3H8N2OHCl CH3CHNH2CONH2HCl Amino Acid Derivatives Alanine Peptide Synthesis Specialty Synthesis Alanine Amino Acid Derivatives Peptide Synthesis Alanine [Ala, A] Amino hydrochloride chiral Amino Acids