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6-BROMO-2-CHLORO-QUINOLINE

6-BROMO-2-CHLORO-QUINOLINE structure

CAS No.: 1810-71-5

Chemical Name:: 6-BROMO-2-CHLORO-QUINOLINE

Synonyms: 6-broMo-2-chloro-;2-Chloro-6-bromoquinoline;6-BROMO-2-CHLORO-QUINOLINE;Quinoline, 6-bromo-2-chloro-;6-Bromo-2-chloroquinoline,96%;4,4'',4''-TRIIODOTRIPHENYLAMINE;6-Bromo-2-chloro-1-azanaphthalene;6-BROMO-2-CHLORO-QUINOLINE ISO 9001：2015 REACH

CBNumber:: CB7772562

Molecular Formula:: C9H5BrClN

Molecular Weight:: 242.5

MDL Number:: MFCD04115272

MOL File:: 1810-71-5.mol

Last updated:2025-07-24 18:13:44

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6-BROMO-2-CHLORO-QUINOLINE Properties

Melting point	148-150℃
Boiling point	325.7±22.0 °C(Predicted)
Density	1.673±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Soluble in Chloroform and Methanol
form	Solid
pka	-0.48±0.43(Predicted)
color	White Crystalline
InChI	InChI=1S/C9H5BrClN/c10-7-2-3-8-6(5-7)1-4-9(11)12-8/h1-5H
InChIKey	YXRDWUJAJLDABJ-UHFFFAOYSA-N
SMILES	N1C2C(=CC(Br)=CC=2)C=CC=1Cl
CAS DataBase Reference	1810-71-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN2811

HS Code

2933499090

NFPA 704

	1
2		0

6-BROMO-2-CHLORO-QUINOLINE price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B5628	6-Bromo-2-chloroquinoline >98.0%(GC)	1810-71-5	1g	$58	2025-07-31	Buy
TCI Chemical	B5628	6-Bromo-2-chloroquinoline >98.0%(GC)	1810-71-5	5g	$231	2025-07-31	Buy
TRC	B682410	6-Bromo-2-chloroquinoline	1810-71-5	1g	$100	2021-12-16	Buy
TRC	B682410	6-Bromo-2-chloroquinoline	1810-71-5	2.5g	$130	2021-12-16	Buy
TRC	B682410	6-Bromo-2-chloroquinoline	1810-71-5	100mg	$45	2021-12-16	Buy

Product number	Packaging	Price	Buy
B5628	1g	$58	Buy
B5628	5g	$231	Buy
B682410	1g	$100	Buy
B682410	2.5g	$130	Buy
B682410	100mg	$45	Buy

6-BROMO-2-CHLORO-QUINOLINE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

It is used as a pharmaceutical intermediate.

Synthesis

1810-66-8

1810-71-5

Step 1: 6-Bromoquinolin-2(1H)-one (1.0 g, 4.4 mmol, 1.0 eq.) was dissolved in phosphoryl chloride (15 mL), stirred and heated to 100 °C, and reacted for 15 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and water was added to the residue. The precipitated solid was collected by filtration and dried under vacuum to give 6-bromo-2-chloroquinoline as a pink solid (1.0 g, 92% yield).LC-MS (ES) m/z = 241.0, 243.0 [M + H]+.1H NMR (400 MHz, DMSO-d6) δ ppm: 7.41 (d, J = 8.4 Hz, 1H), 7.79-7.82 ( m, 1H), 7.89 (d, J = 9.2 Hz, 1H), 7.98-7.99 (m, 1H), 8.02 (d, J = 8.8 Hz, 1H).

References

[1] Patent: WO2017/46739, 2017, A1. Location in patent: Page/Page column 78
[2] Journal of the American Chemical Society, 2016, vol. 138, # 25, p. 7808 - 7811
[3] Patent: WO2006/132739, 2006, A2. Location in patent: Page/Page column 36
[4] European Journal of Medicinal Chemistry, 2000, vol. 35, # 10, p. 931 - 940
[5] Patent: WO2009/39127, 2009, A1. Location in patent: Page/Page column 181

6-BROMO-2-CHLORO-QUINOLINE Preparation Products And Raw materials

Raw materials

6-BROMO-2(1H)-QUINOLONE 6-bromo-1-oxido-quinoline

Preparation Products

2-CHLOROQUINOLINE-6-CARBALDEHYDE 6-Bromoquinolin-2-amine

6-BROMO-2-CHLORO-QUINOLINE Suppliers

Global( 268)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29731	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Chembon Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Yunbio Tech Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 6-BROMO-2-CHLORO-QUINOLINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-03-04	6-BROMO-2-CHLORO-QUINOLINE 1810-71-5	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
	2019-07-07	6-BROMO-2-CHLORO-QUINOLINE 1810-71-5	US $1.00 / KG	1KG	99%	100kg	Career Henan Chemical Co

6-BROMO-2-CHLORO-QUINOLINE
1810-71-5
US $1.10 / g
99.00%
Dideu Industries Group Limited

6-BROMO-2-CHLORO-QUINOLINE
1810-71-5
US $1.00 / KG
99%
Career Henan Chemical Co

6-BROMO-2-CHLORO-QUINOLINE Spectrum

6-BROMO-2-CHLORO-QUINOLINE(1810-71-5)¹HNMR 6-BROMO-2-CHLORO-QUINOLINE(1810-71-5)FT-IR

1810-71-5(6-BROMO-2-CHLORO-QUINOLINE)Related Search:

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Quinoline, 6-bromo-2-chloro- 6-broMo-2-chloro- 6-Bromo-2-chloro-1-azanaphthalene 6-BROMO-2-CHLORO-QUINOLINE 2-Chloro-6-bromoquinoline 4,4'',4''-TRIIODOTRIPHENYLAMINE 6-Bromo-2-chloroquinoline,96% 6-BROMO-2-CHLORO-QUINOLINE ISO 9001：2015 REACH 1810-71-5 CHIRAL CHEMICALS Aromatics Heterocycles Aromatics Compounds