ChemicalBook >> CAS DataBase List >>5-Bromothiophene-2-carbaldehyde

5-Bromothiophene-2-carbaldehyde

5-Bromothiophene-2-carbaldehyde structure

CAS No.: 4701-17-1

Chemical Name:: 5-Bromothiophene-2-carbaldehyde

Synonyms: 5-BROMO-THIOPHENE-2-CARBALDEHYDE;5-BROMOTHIOPHENE-2-CARBOXALDEHYDE;5-BROMO-2-THIOPHENECARBOXALDEHYDE;EA356;AKOS BBS-00003268;TIMTEC-BB SBB000294;5-bromothenaldehyde;5-Bromothiophene-2-c;LABOTEST-BB LT00112291;5-BROMO-2-FORMYLTHIOPHENE

CBNumber:: CB7780945

Molecular Formula:: C5H3BrOS

Molecular Weight:: 191.05

MDL Number:: MFCD00005432

MOL File:: 4701-17-1.mol

MSDS File:: SDS

Last updated:2026-01-13 11:26:10

Product description	Number	Pack Size	Price
5-Bromo-2-thiophenecarboxaldehyde 95%	152625	25g	$201
5-Bromo-2-thiophenecarboxaldehyde 95%	152625	100g	$540.4
5-Bromothiophene-2-carboxaldehyde >97.0%(GC)	B1135	5g	$34
5-Bromothiophene-2-carboxaldehyde >97.0%(GC)	B1135	25g	$133
5-Bromo-2-thiophenecarboxaldehyde	B688130	10g	$50
More product size

Request For Quotation

5-Bromothiophene-2-carbaldehyde Properties

Melting point	55°C
Boiling point	105-107 °C11 mm Hg(lit.)
Density	1.607 g/mL at 25 °C(lit.)
refractive index	n20/D 1.637(lit.)
Flash point	210 °F
storage temp.	2-8°C
solubility	Soluble in chloroform and methanol.
form	Liquid After Melting
color	Clear yellow to brown
Sensitive	Air Sensitive
BRN	108404
InChI	1S/C5H3BrOS/c6-5-2-1-4(3-7)8-5/h1-3H
InChIKey	GFBVUFQNHLUCPX-UHFFFAOYSA-N
SMILES	[H]C(=O)c1ccc(Br)s1
LogP	2.566 (est)
CAS DataBase Reference	4701-17-1(CAS DataBase Reference)
NIST Chemistry Reference	5-Bromo-2-thiophenecarboxaldehyde(4701-17-1)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Xn,Xi

Risk Statements

36/37/38-20/21/22

Safety Statements

36/37/39-26-22-36

WGK Germany

Hazard Note

Irritant/Air Sensitive

TSCA

HS Code

29349990

Storage Class

11 - Combustible Solids

NFPA 704

	1
1		0

5-Bromothiophene-2-carbaldehyde price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	152625	5-Bromo-2-thiophenecarboxaldehyde 95%	4701-17-1	25g	$201	2025-07-31	Buy
Sigma-Aldrich	152625	5-Bromo-2-thiophenecarboxaldehyde 95%	4701-17-1	100g	$540.4	2025-07-31	Buy
TCI Chemical	B1135	5-Bromothiophene-2-carboxaldehyde >97.0%(GC)	4701-17-1	5g	$34	2025-07-31	Buy
TCI Chemical	B1135	5-Bromothiophene-2-carboxaldehyde >97.0%(GC)	4701-17-1	25g	$133	2025-07-31	Buy
TRC	B688130	5-Bromo-2-thiophenecarboxaldehyde	4701-17-1	10g	$50	2021-12-16	Buy

Product number	Packaging	Price	Buy
152625	25g	$201	Buy
152625	100g	$540.4	Buy
B1135	5g	$34	Buy
B1135	25g	$133	Buy
B688130	10g	$50	Buy

5-Bromothiophene-2-carbaldehyde Chemical Properties,Uses,Production

Chemical Properties

clear yellow to brown liquid after melting

Uses

5-Bromo-2-thiophenecarboxaldehyde was used to prepare 5-[18F]fluoro-2-2-thiophene carboxaldehyde. Also is used in biological studies as anti-inflammatory and anti-tumor activity of the marine mangrove Rhizophora apiculata.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 1422, 1950 DOI: 10.1021/ja01159a527

Synthesis

98-03-3

4701-17-1

2.1.1 Synthesis of 5-bromo-2-thiophenecarboxaldehyde Under nitrogen protection, 2-thiophenecarboxaldehyde (6.0 g, 53.5 mmol) was dissolved in anhydrous chloroform (125 mL). Subsequently, N-bromosuccinimide (10.4 g, 58.9 mmol) was slowly added and the reaction mixture was stirred for 12 h at room temperature. After completion of the reaction, the mixture was extracted with chloroform (3 × 50 mL), and the organic phases were combined and washed with deionized water (2 × 50 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using chloroform as eluent to afford 5-bromo-2-thiophenecarboxaldehyde as a colorless oil (10.0 g, 98% yield). 1H NMR (400 MHz, CDCl3): δ 7.20 (d, 1H, J = 4.0 Hz), 7.53 (d, 1H, J = 8.0 Hz), 9.79 (s, 1H).

References

[1] Physica B: Condensed Matter, 2017, vol. 519, p. 53 - 58
[2] Tetrahedron, 2007, vol. 63, # 37, p. 9188 - 9194
[3] Tetrahedron Letters, 2005, vol. 46, # 12, p. 1989 - 1992
[4] Patent: WO2018/67786, 2018, A1. Location in patent: Page/Page column 134; 135
[5] Journal of the Chemical Society, 1958, p. 1721

5-Bromothiophene-2-carbaldehyde synthesis

Synthesis of 5-Bromothiophene-2-carbaldehyde from 2-Thiophenecarboxaldehyde

5-Bromothiophene-2-carbaldehyde Preparation Products And Raw materials

Raw materials

Triphosgene N,N-Dimethylformamide 2-Bromothiophene Phosphorus oxybromide Carbon tetrachloride

Chlorobenzene N-Methylformanilide Thiophene, 2-bromo-5-(chloromethyl)- 2-Bromo-5-methylthiophene 5-Bromo-2-thiophenecarboxylic acid

5-BROMOTHIOPHEN-2-YLMETHYLAMINE Ethyl 5-bromothiophene-2-carboxylate

1of3

Preparation Products

[2，2’]bithiophenyl-5,5'-dicarbaldehyde 5-BROMO-2,2'-BITHIOPHENE-5'-CARBOXALDEHYDE 1-(5-BROMOTHIEN-2-YL)ETHANAMINE 2-Propenoic acid, 3-(5-broMo-2-thienyl)-

5-Bromothiophene-2-carbaldehyde Suppliers

Global( 380)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13620	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21599	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58
Changzhou Carman Chemical Co., Ltd.	15061933924		CHINA	514	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
HaBo Hong Kong Co., Limited.	58
Jinan Finer Chemical Co., Ltd	58
Changzhou Carman Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 5-Bromothiophene-2-carbaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	5-Bromothiophene-2-carbaldehyde 4701-17-1	US $1.10 / h	1h	99.00%	100 Tons	Dideu Industries Group Limited
2025-04-04	5-Bromothiophene-2-carbaldehyde 4701-17-1	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2022-09-01	5-bromothiophene 2-formaldehyde 4701-17-1	US $0.00-0.00 / g	10g	95%	10kg	Zhengzhou Gecko Scientific Inc.

5-Bromothiophene-2-carbaldehyde
4701-17-1
US $1.10 / h
99.00%
Dideu Industries Group Limited

5-Bromothiophene-2-carbaldehyde
4701-17-1
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

5-bromothiophene 2-formaldehyde
4701-17-1
US $0.00-0.00 / g
95%
Zhengzhou Gecko Scientific Inc.

5-Bromothiophene-2-carbaldehyde Spectrum

5-Bromothiophene-2-carbaldehyde(4701-17-1)MS 5-Bromothiophene-2-carbaldehyde(4701-17-1)¹HNMR 5-Bromothiophene-2-carbaldehyde(4701-17-1)¹³CNMR 5-Bromothiophene-2-carbaldehyde(4701-17-1)IR1 5-Bromothiophene-2-carbaldehyde(4701-17-1)Raman

4701-17-1(5-Bromothiophene-2-carbaldehyde)Related Search:

Cephalothin sodium 2-Thiophenecarboxaldehyde Thifensulfuron methyl Tetrahydrothiophene 5-Bromothiazole

Ethyl 5-bromothiophene-2-carboxylate 5-Bromothiophenesulfonyl chloride 5-Bromothiophene-2-sulfonamide METHYL4,5-DIBROMOTHIOPHENE-2-CARBOXYLATE 2-Thiophenecarboxylic acid, 4-amino-5-bromo-

2-Acetyl-5-bromothiophene 2-BROMO-1-(5-BROMOTHIOPHEN-2-YL)ETHANONE 4,5-DIBROMOTHIOPHENE-2-CARBOXALDEHYDE 5-Bromothiophene-2-carbohydrazide 5-Bromo-2-thiophenecarboxylic acid

4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE Bromine

1of4

2-Thiophenecarboxaldehyde, 5-bromo- LABOTEST-BB LT00112291 5-BROMO-2-THIOPHENECARBALDEHYDE 5-BROMO-2-THIOPHENECARBOXALDEHYDE 5-BROMO-2-FORMYLTHIOPHENE 5-BROMOTHIOPHENE-2-ALDEHYDE 5-BROMO-THIOPHENE-2-CARBALDEHYDE 5-BROMOTHIOPHENE-2-CARBOXALDEHYDE AKOS BBS-00003268 TIMTEC-BB SBB000294 5-BROMOTHIOPHENE-2-CARBALDEHYDE 98% 2-BROMO-5-THIOPHENECARBOXALDEHYDE 5-Bromothiophene-2-Aldehyde98% 5-Bromothiophene-2-Aldehyde 98% 2-BROMOTHIOPHENE-5-CARBOXALDEHYDE 5-bromothenaldehyde 5-BROMO-2-THIIOPHENE CARBOXALDEHYDE 5-Bromo-2-thiophenecarboxaL 5-bromothiophere-2-carbaldehyde 5-Bromo-2-thiophenecarboxaldehyde,97% 5-Bromo-2-thienylaldehyde 5-Bromothiophene-2-c 5-BroMo-2-thiophenecarboxaldehyde, 97% 25ML 2-BroMo-5-forMylthiophene 5-Bromo-2-formylthiophene, 5-Bromo-2-thenaldehyde 5-BroMothiophene-2-carboxaldehyde,5-BroMo-2-forMylthiophene 5-BroMo-2-thiophenecarboxaldehyde (>90%) 5-BroMo-2-thiophenecarboxaldehyde 95% 5-BroMo-2-thiophenecarboxaldehyde, 98%+ 5-Bromothiophene-2-carboxaldehyde,97% JR-8910, 5-Bromo-2-thiophenecarboxaldehyde, 95% 5-Bromothiophene-2-carboxaldehyde > 5-Bromothiophene-2-carbaldehyde ISO 9001：2015 REACH EA356 5-Bromothiophene-2-carbaldehyde,4701-17-1 5-bromothiophene 2-formaldehyde 5-bromo-2-thiophencarboxaldehyde 4701-17-1 4710-17-1 C5H3O2BrS ALDEHYDE Heterocyclic Building Blocks Halogenated Heterocycles Thiophenes Building Blocks Heterocycle-oher series alkyl bromide Thiophenes & Benzothiophenes Azoles blocks Bromides Heterocycles Aldehydes Thiophenes & Benzothiophenes bc0001