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Lp-PLA2-IN-3

Lp-PLA2-IN-3 Structure
Lp-PLA2-IN-3 structure
CAS No.
2196245-16-4
Chemical Name:
Lp-PLA2-IN-3
Synonyms
Lp-PLA2-IN-3;Lp-PLA2-IN-3, 10 mM in DMSO;LpPLA2IN3,Lp-PLA-2-IN-3,Lp PLA2 IN 3;Benzenesulfonamide, 4-amino-N-[4-[4-chloro-3-(trifluoromethyl)phenoxy]-3-cyanophenyl]-
CBNumber:
CB78039041
Molecular Formula:
C20H13ClF3N3O3S
Molecular Weight:
467.85
MDL Number:
MFCD32689601
MOL File:
2196245-16-4.mol
Last updated:2025-09-24 14:33:23
Product description Number Pack Size Price
Lp-PLA2-IN-3 99.47% CS-0112334 5mg $350
Lp-PLA2-IN-3 99.47% CS-0112334 10mg $550
Lp-PLA2-IN-3 99.47% CS-0112334 50mg $1650
Lp-PLA2-IN-3 99.47% CS-0112334 100mg $2250
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Lp-PLA2-IN-3 Properties

Boiling point 584.5±60.0 °C(Predicted)
Density 1.57±0.1 g/cm3(Predicted)
pka 7.21±0.10(Predicted)
form Solid
color White to off-white

Lp-PLA2-IN-3 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0112334 Lp-PLA2-IN-3 99.47% 2196245-16-4 5mg $350 2021-12-16 Buy
ChemScene CS-0112334 Lp-PLA2-IN-3 99.47% 2196245-16-4 10mg $550 2021-12-16 Buy
ChemScene CS-0112334 Lp-PLA2-IN-3 99.47% 2196245-16-4 50mg $1650 2021-12-16 Buy
ChemScene CS-0112334 Lp-PLA2-IN-3 99.47% 2196245-16-4 100mg $2250 2021-12-16 Buy
Product number Packaging Price Buy
CS-0112334 5mg $350 Buy
CS-0112334 10mg $550 Buy
CS-0112334 50mg $1650 Buy
CS-0112334 100mg $2250 Buy

Lp-PLA2-IN-3 Chemical Properties,Uses,Production

Uses

Lp-PLA2-IN-3 is a potent and orally bioavailable lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 14 nM for recombinant human Lp-PLA2 (rhLpPLA2)[1].

in vivo

Lp-PLA2-IN-3 (3 mg/kg; p.o.) treatment shows the Cmax, AUC0-24h, t1/2 and F were 0.27 μg/mL, 3.4 μg h/mL, 7.7 hours and 35.5%, respectively[1].
Lp-PLA2-IN-3 (1 mg/kg; i.v.) treatment shows the CL, Vss, and t1/2 were 3.1mL/min/kg, 0.3 L/kg, 4 hours, respectively[1].

Animal Model:Male Sprague?Dawley (SD) rats (180-220 g)[1]
Dosage:3 mg/kg
Administration:p.o. (Pharmacokinetic Analysis)
Result:The Cmax, AUC0-24h, t1/2 and F were 0.27 μg/mL, 6.2 μg h/mL, 7.7 hours and 35.5%, respectively.

References

[1] Liu Q, et al. Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2. J Med Chem. 2017 Dec 28;60(24):10231-10244. DOI:10.1021/acs.jmedchem.7b01530

Lp-PLA2-IN-3 Preparation Products And Raw materials

Raw materials

Preparation Products

Lp-PLA2-IN-3 Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39032 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772 huahero21@sina.com China 2174 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9835 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29547 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 6710 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 6051 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Shanghai Beckham Medical Technology Co., Ltd 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58
Sangon Biotech (Shanghai) Co.,Ltd. 58
Biosynth Biological Technology (Suzhou) Co Ltd 58

View Lastest Price from Lp-PLA2-IN-3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lp-PLA2-IN-3 pictures 2025-09-23 Lp-PLA2-IN-3
2196245-16-4
 US $97.00-378.00 / mg 99.65% 10g TargetMol Chemicals Inc.
Lp-PLA2-IN-3 pictures 2025-09-23 Lp-PLA2-IN-3
2196245-16-4
 US $97.00-378.00 / mg 99.65% 10g TargetMol Chemicals Inc.
  • Lp-PLA2-IN-3 pictures
  • Lp-PLA2-IN-3
    2196245-16-4
  • US $97.00-378.00 / mg
  • 99.65%
  • TargetMol Chemicals Inc.
  • Lp-PLA2-IN-3 pictures
  • Lp-PLA2-IN-3
    2196245-16-4
  • US $97.00-378.00 / mg
  • 99.65%
  • TargetMol Chemicals Inc.
Lp-PLA2-IN-3 LpPLA2IN3,Lp-PLA-2-IN-3,Lp PLA2 IN 3 Benzenesulfonamide, 4-amino-N-[4-[4-chloro-3-(trifluoromethyl)phenoxy]-3-cyanophenyl]- Lp-PLA2-IN-3, 10 mM in DMSO 2196245-16-4