Biotin-PEG4-amino-t-Bu-DADPS-C6-azide
- CAS No.
- 1260247-50-4
- Chemical Name:
- Biotin-PEG4-amino-t-Bu-DADPS-C6-azide
- Synonyms
- DADPS Biotin Azide;DADPS Biotin Azide Dadps;Biotin-PEG4-amino-t-Bu-DADPS-C6-azide;N-(2-((((6-Azidohexyl)oxy)diphenylsilyl)oxy)-2-methylpropyl)-1-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)-3,6,9,12-tetraoxapentadecan-15-amide
- CBNumber:
- CB78054673
- Molecular Formula:
- C43H67N7O9SSi
- Molecular Weight:
- 886.19
- MDL Number:
- MFCD32069538
- MOL File:
- 1260247-50-4.mol
Product description | Number | Pack Size | Price |
DADPSbiotinazide | 35159 | 1MG | $134.4 |
DADPSBiotinAzide 90% | BP-24315 | 5mg | $239 |
DADPSbiotinazide | 35159 | 5MG | $291.2 |
DADPSBiotinAzide 90% | BP-24315 | 25mg | $679 |
DADPSbiotinazide | 35159 | 25MG | $896.9 |
storage temp. | Storage temp. -20°C |
---|---|
solubility | DMSO: 100 mg/mL (112.84 mM) |
form | Solid |
color | Off-white to light yellow |
InChIKey | CSHHHVOFXKFHMG-JUSAZYRUNA-N |
SMILES | [Si](C1C=CC=CC=1)(C1C=CC=CC=1)(OCCCCCCN=[N+]=[N-])OC(C)(C)CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@]2([H])NC(=O)N[C@]12[H] |&1:52,55,61,r| |
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Chem-Impex | 35159 | DADPSbiotinazide | 1260247-50-4 | 1MG | $134.4 | 2021-12-16 | Buy |
BroadPharm | BP-24315 | DADPSBiotinAzide 90% | 1260247-50-4 | 5mg | $239 | 2021-12-16 | Buy |
Chem-Impex | 35159 | DADPSbiotinazide | 1260247-50-4 | 5MG | $291.2 | 2021-12-16 | Buy |
BroadPharm | BP-24315 | DADPSBiotinAzide 90% | 1260247-50-4 | 25mg | $679 | 2021-12-16 | Buy |
Chem-Impex | 35159 | DADPSbiotinazide | 1260247-50-4 | 25MG | $896.9 | 2021-12-16 | Buy |
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide Chemical Properties,Uses,Production
Description
DADPS Biotin Azide probes eliminate a major limitation of the streptavidin-biotin affinity purification. This reagent contains a biotin moiety and an azide moiety. DADPS probe can be used in biomolecular labeling and proteomic studies. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
Uses
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32434 | 58 |
Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19961 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
ComMedX (Computational Medicine Beijing Co., Ltd.) | +86-18519000250 +86-18519000250 | zhanghu@commedx.com | China | 258 | 58 |
View Lastest Price from Biotin-PEG4-amino-t-Bu-DADPS-C6-azide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2025-10-18 | DADPS Biotin Azide
1260247-50-4
|
US $95.00-372.00 / mg | 95.00% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2025-06-07 | Biotin-Dadps-azide
1260247-50-4
|
US $0.00 / mg | 250mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- DADPS Biotin Azide
1260247-50-4
- US $95.00-372.00 / mg
- 95.00%
- TargetMol Chemicals Inc.
-
- Biotin-Dadps-azide
1260247-50-4
- US $0.00 / mg
- >95.00%
- Xian confluore Biological Technology Co., Ltd.