Lutikizumab
- CAS No.
- 1791411-57-8
- Chemical Name:
- Lutikizumab
- Synonyms
- Lutikizumab;Research Grade Lutikizumab
- CBNumber:
- CB78080997
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | 15FAZ725S0 |
Lutikizumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0628997 | Lutikizumab 96.54% | 1791411-57-8 | 1mg | $596 | 2026-06-04 | Buy |
| ChemScene | CS-0628997 | Lutikizumab 96.54% | 1791411-57-8 | 5mg | $1517 | 2026-06-04 | Buy |
| ChemScene | CS-0628997 | Lutikizumab 96.54% | 1791411-57-8 | 10mg | $2427 | 2026-06-04 | Buy |
| ChemScene | CS-0628997 | Lutikizumab 96.54% | 1791411-57-8 | 25mg | $4333 | 2026-06-04 | Buy |
| ChemScene | CS-0628997 | Lutikizumab 96.54% | 1791411-57-8 | 50mg | $6500 | 2026-06-04 | Buy |
Lutikizumab Chemical Properties,Uses,Production
Uses
Lutikizumab (ABT-981) is an anti-IL-1α and IL-1β dual variable domain immunoglobulin. Lutikizumab binds and inhibits IL-1α and IL-1β. Lutikizumab can be used for the research of osteoarthritis[1].
in vivo
Lutikizumab (0.0001-1 mg/kg, i.p., once) shows effective inhibition to the IL-6 production induced by IL-1α and IL-1β[1].
| Animal Model: | Female C57/BL6 mice with IL-1α and IL-1β injection[1] |
| Dosage: | 0.0001-1 mg/kg |
| Administration: | Intraperitoneal injection, 0.0001-1 mg/kg, once |
| Result: | Dose-dependently decreased the murine IL-6 generated by human and cynomolgus IL-1α and IL-1β. |
References
[1] Lacy SE, et al. Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-Ig(TM)) molecule that specifically and potently neutralizes both IL-1α and IL-1β. MAbs. 2015;7(3):605-19. DOI:10.1080/19420862.2015.1026501
Lutikizumab Preparation Products And Raw materials
Raw materials
Preparation Products
Lutikizumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Changsha Fuzhen Biotechnology Co.，LTD | 15111215862 18229892877 | 3062105966@qq.com | China | 5550 | 58 |
| Olix ( Hubei) Pharmaceutical Technology Co., Ltd | 17316404525 17316404525 | 209533805@qq.com | China | 9769 | 58 |
