Murlentamab
- CAS No.
- 2058047-65-5
- Chemical Name:
- Murlentamab
- Synonyms
- Murlentamab;3C23K|||GM102;Murlentamab (anti-AMHR2);Research Grade Murlentamab;Research Grade Murlentamab (DHH34701)
- CBNumber:
- CB78081095
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | ZN0DUZ3M4L |
Murlentamab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0629140 | Murlentamab 95.00% | 2058047-65-5 | 1mg | $282 | 2026-06-04 | Buy |
| ChemScene | CS-0629140 | Murlentamab 95.00% | 2058047-65-5 | 5mg | $737 | 2026-06-04 | Buy |
| ChemScene | CS-0629140 | Murlentamab 95.00% | 2058047-65-5 | 10mg | $1137 | 2026-06-04 | Buy |
| aablocks | AA02A406 | Murlentamab ≥95%(SDS-PAGE&SEC-HPLC) | 2058047-65-5 | 1mg | $560 | 2026-06-02 | Buy |
| aablocks | AA02A406 | Murlentamab ≥95%(SDS-PAGE&SEC-HPLC) | 2058047-65-5 | 5mg | $1510 | 2026-06-02 | Buy |
Murlentamab Chemical Properties, Uses, Production
Uses
Murlentamab (3C23K; GM102) is a humanized anti-AMHRII antibody. AMHRII is the anti-Müllerian hormone receptor. Murlentama significantly promotes macrophage-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Murlentama stimulates pro-inflammatory and anti-tumor internal environment, recruits and activates T cells. Murlentama suppresses tumors growth by inducing nave macrophage orientation and promoting tumor-associated macrophage (TAM) reprogramming[1].
in vivo
Murlentamab (20 mg/kg; i.v.; twice weekly for 4 weeks) inhibits tumor growth in mouse hepatocarcinoma PDX model in vivo[2].
References
[1] Prat M, et al. Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation. Cancers (Basel). 2021 Apr 13;13(8):1845. DOI:10.3390/cancers13081845
[2] Barret JM, et al. The Expression of Anti-Müllerian Hormone Type II Receptor (AMHRII) in Non-Gynecological Solid Tumors Offers Potential for Broad Therapeutic Intervention in Cancer. Biology (Basel). 2021 Apr 7;10(4):305. DOI:10.3390/biology10040305
Murlentamab Preparation Products And Raw materials
Raw materials
Preparation Products
Murlentamab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
| Changsha Fuzhen Biotechnology Co.，LTD | 15111215862 18229892877 | 3062105966@qq.com | China | 5569 | 58 |
