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Methyl Indoline-6-carboxylate

CAS No.
341988-36-1
Chemical Name:
Methyl Indoline-6-carboxylate
Synonyms
methyl indoline-6-carboxylate;methyl indoline-6-carboxylate - [M23157];Methyl 2,3-dihydro-1H-indole-6-carboxylate;Methyl2,3-dihydro-1H-indole-6-carboxylatato;Methyl indoline-6-carboxylate in stock Factory;1H-INDOLE-6-CARBOXYLIC ACID,2,3-DIHYDRO-,METHYL ESTER;2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
CBNumber:
CB7843433
Molecular Formula:
C10H11NO2
Molecular Weight:
177.2
MDL Number:
MFCD07371629
MOL File:
341988-36-1.mol
MSDS File:
SDS
Last updated:2025-08-18 19:12:29
Product description Number Pack Size Price
Methylindoline-6-carboxylate M313608 100mg $50
2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester FD56698 25mg $88.5
Methylindoline-6-carboxylate W5567 250mg $151
2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester FD56698 50mg $181
Methylindoline-6-carboxylate 98% OR910526 1g $230
More product size

Methyl Indoline-6-carboxylate Properties

Boiling point 315.6±31.0 °C(Predicted)
Density 1.162±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 4.26±0.20(Predicted)
Appearance White to yellow Solid
InChI InChI=1S/C10H11NO2/c1-13-10(12)8-3-2-7-4-5-11-9(7)6-8/h2-3,6,11H,4-5H2,1H3
InChIKey IVFIWGSRKYSLLR-UHFFFAOYSA-N
SMILES N1C2=C(C=CC(C(OC)=O)=C2)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  29339900

Methyl Indoline-6-carboxylate price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M313608 Methylindoline-6-carboxylate 341988-36-1 100mg $50 2021-12-16 Buy
Biosynth Carbosynth FD56698 2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester 341988-36-1 25mg $88.5 2021-12-16 Buy
AK Scientific W5567 Methylindoline-6-carboxylate 341988-36-1 250mg $151 2021-12-16 Buy
Biosynth Carbosynth FD56698 2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester 341988-36-1 50mg $181 2021-12-16 Buy
Apolloscientific OR910526 Methylindoline-6-carboxylate 98% 341988-36-1 1g $230 2021-12-16 Buy
Product number Packaging Price Buy
M313608 100mg $50 Buy
FD56698 25mg $88.5 Buy
W5567 250mg $151 Buy
FD56698 50mg $181 Buy
OR910526 1g $230 Buy

Methyl Indoline-6-carboxylate Chemical Properties,Uses,Production

Chemical Properties

White solid

Synthesis

Methyl indole-6-carboxylate

50820-65-0

Methyl Indoline-6-carboxylate

341988-36-1

Step 1: Methyl indole-6-carboxylate (534 mg, 3.05 mmol) was dissolved in acetic acid (7.5 mL) and the solution was cooled to 0°C. Sodium cyanoborohydride (580 mg, 9.2 mmol, 3 equiv) was added to the solution in batches with stirring. The reaction mixture was stirred continuously for 40 minutes at 15 °C. Subsequently, sodium cyanoborohydride (193 mg, 3.05 mmol, 1 eq.) was added again and stirring was continued for 30 minutes at room temperature. After completion of the reaction, the solvent was removed by rotary evaporator. The residue was dissolved in dichloromethane and washed with 1N NaOH solution. The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated to afford methyl 2,3-dihydro-1H-indole-6-carboxylate as a pale yellow solid in a yield of 494 mg (77% yield). The product did not require further purification and could be used directly in the subsequent reaction.

References

[1] Patent: US2007/60567, 2007, A1. Location in patent: Page/Page column 25
[2] Patent: US2008/153805, 2008, A1. Location in patent: Page/Page column 12
[3] ChemMedChem, 2016, vol. 11, # 23, p. 2607 - 2620
[4] Patent: WO2018/52903, 2018, A1. Location in patent: Page/Page column 22; 43-44
[5] Patent: US2010/234340, 2010, A1. Location in patent: Page/Page column 20

Methyl Indoline-6-carboxylate Preparation Products And Raw materials

Global( 108)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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Accela ChemBio Inc.
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CONIER CHEM AND PHARMA LIMITED
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View Lastest Price from Methyl Indoline-6-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 2,3-dihydro-1H-indole-6-carboxylate pictures 2025-10-13 Methyl 2,3-dihydro-1H-indole-6-carboxylate
341988-36-1
US $1.10-9.90 / kg 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Methyl indoline-6-carboxylate   in stock Factory pictures 2020-06-02 Methyl indoline-6-carboxylate in stock Factory
341988-36-1
US $1.00 / KG 1KG TOP 3 Factory in China Top 3 production capacity Factory Chemwill Asia Co.,Ltd.
2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE pictures 2020-01-10 2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
341988-36-1
US $1.00 / KG 1KG 98% 200kgs Career Henan Chemical Co

Methyl Indoline-6-carboxylate Spectrum

Methyl indoline-6-carboxylate in stock Factory Methyl 2,3-dihydro-1H-indole-6-carboxylate 2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE methyl indoline-6-carboxylate Methyl2,3-dihydro-1H-indole-6-carboxylatato 1H-INDOLE-6-CARBOXYLIC ACID,2,3-DIHYDRO-,METHYL ESTER methyl indoline-6-carboxylate - [M23157] 341988-36-1 Heterocycles