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5-Amino-2-bromopyridine

5-Amino-2-bromopyridine structure

CAS No.: 13534-97-9

Chemical Name:: 5-Amino-2-bromopyridine

Synonyms: 6-BROMOPYRIDIN-3-AMINE;5-BROMO-PYRIDIN-2-YLAMINE;2-Bromo-5;AKOS BBS-00004444;TIMTEC-BB SBB003823;TIMTEC-BB SBB005540;LABOTEST-BB LT00129606;2-Bromo-5-aminoyridine;6-BROMO-3-PYRIDINAMINE;5-amine-2-bromopyridin

CBNumber:: CB7853072

Molecular Formula:: C5H5BrN2

Molecular Weight:: 173.01

MDL Number:: MFCD01646116

MOL File:: 13534-97-9.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:42

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5-Amino-2-bromopyridine Properties

Melting point	75 °C
Boiling point	180 °C
Density	1.6065 (rough estimate)
refractive index	1.5182 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	1.87±0.10(Predicted)
form	Powder
color	Beige to brown-black
BRN	109102
InChI	InChI=1S/C5H5BrN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H2
InChIKey	XTHKRYHULUJQHN-UHFFFAOYSA-N
SMILES	C1=NC(Br)=CC=C1N
CAS DataBase Reference	13534-97-9(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

36/37/38

Safety Statements

26-36-37/39

RIDADR

UN 2811 6.1/PG 3

WGK Germany

HazardClass

IRRITANT

PackingGroup

III

HS Code

29333990

NFPA 704

	1
2		0

5-Amino-2-bromopyridine price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	552844	3-Amino-6-bromopyridine 97%	13534-97-9	5g	$37.5	2025-07-31	Buy
Sigma-Aldrich	552844	3-Amino-6-bromopyridine 97%	13534-97-9	1g	$48	2023-06-20	Buy
TCI Chemical	A1890	5-Amino-2-bromopyridine >97.0%(GC)	13534-97-9	1g	$36	2025-07-31	Buy
TCI Chemical	A1890	5-Amino-2-bromopyridine >97.0%(GC)	13534-97-9	5g	$108	2025-07-31	Buy
TRC	A601875	5-Amino-2-bromopyridine	13534-97-9	25g	$455	2021-12-16	Buy

Product number	Packaging	Price	Buy
552844	5g	$37.5	Buy
552844	1g	$48	Buy
A1890	1g	$36	Buy
A1890	5g	$108	Buy
A601875	25g	$455	Buy

5-Amino-2-bromopyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow needles

Uses

3-Amino-6-bromopyridine may undergo polymerization via Buchwald–Hartwig amination in the presence of sodium tert-butoxide and XPhos(2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl) ligand yielding para-linked and meta-linked polyaminopyridines.

General Description

3-Amino-6-bromopyridine can be synthesized via bromination of 3-aminopyridine using N-bromosuccinimide in acetonitrile.

Synthesis

4487-59-6

13534-97-9

General procedure for the synthesis of 5-amino-2-bromopyridine from 2-bromo-5-nitropyridine: To a solution of 2-bromo-5-nitropyridine (2.03 g, 10 mmol) in ethanol (48 mL) was added sequentially iron powder (2.8 g, 50 mmol), concentrated hydrochloric acid (1.9 mL) and water (9.1 mL). The reaction mixture was stirred under reflux conditions for 5 hours. After completion of the reaction, it was cooled to room temperature and filtered. The filtrate was concentrated under reduced pressure, the pH was adjusted to 7-8 with base and subsequently extracted with dichloromethane (DCM). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the reddish brown solid product 5-amino-2-bromopyridine (1.58 g, 91.3% yield).

References

[1] Bulletin des Societes Chimiques Belges, 1988, vol. 97, # 1, p. 51 - 54
[2] Green Chemistry, 2018, vol. 20, # 1, p. 130 - 135
[3] Journal of Organic Chemistry, 2011, vol. 76, # 23, p. 9841 - 9844
[4] Patent: EP2886540, 2015, A1. Location in patent: Paragraph 0143; 0144
[5] Patent: US2014/93505, 2014, A1. Location in patent: Page/Page column

5-Amino-2-bromopyridine synthesis

Synthesis of 5-Amino-2-bromopyridine from 2-Bromo-5-nitropyridine

5-Amino-2-bromopyridine Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate Aluminium-nickel PHOSPHORUS PENTABROMIDE Phosphorus oxybromide 2-Bromo-5-nitropyridine

Hydrochloric acid Iron Phosphorus tribromide 2-Hydroxy-5-nitropyridine 3-Amino-2-bromopyridine

3-Aminopyridine 2,6-Dibromopyridin-3-amine 2-Amino-5-nitropyridine

1of3

Preparation Products

6-Bromoimidazo[1,2-a]pyridine ethyl 4,6-dichloro-1,5-naphthyridine-3-carboxylate 2,2'-bipyridine-5,5'-diamine 3-Amino-6-morpholinopyridine 2-Bromo-5-iodopyridine

5-Amino-2-bromopyridine Suppliers

Global( 517)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20202	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29733	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
HaBo Hong Kong Co., Limited.	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58

View Lastest Price from 5-Amino-2-bromopyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-07-25	5-Amino-2-bromopyridine 13534-97-9	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-04-04	5-Amino-2-bromopyridine 13534-97-9	US $0.00-0.00 / KG	1KG	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2024-04-08	5-Amino-2-bromopyridine 13534-97-9	US $5.00-0.10 / KG	1KG	98%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

5-Amino-2-bromopyridine
13534-97-9
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

5-Amino-2-bromopyridine
13534-97-9
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

5-Amino-2-bromopyridine
13534-97-9
US $5.00-0.10 / KG
98%
Henan Fengda Chemical Co., Ltd

5-Amino-2-bromopyridine Spectrum

5-Amino-2-bromopyridine(13534-97-9)¹HNMR 5-Amino-2-bromopyridine(13534-97-9)FT-IR

13534-97-9(5-Amino-2-bromopyridine)Related Search:

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2-Bromo-5-methylpyridine 2-Bromo-6-(trifluoromethyl)pyridine 2-Bromo-6-methylpyridine

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2-Bromo-5-aminoyridine 6-BROMOPYRIDIN-3-AMINE TIMTEC-BB SBB005540 TIMTEC-BB SBB003823 LABOTEST-BB LT00129606 2-BROMO-5-AMINOPYRIDINE 5-BROMO-2-AMINOPYRIDINE 5-AMINO-2-BROMOPYRIDINE 3-AMINO-6-BROMOPYRIDINE AKOS BBS-00004444 5-BROMO-PYRIDIN-2-YLAMINE 6-BROMO-3-PYRIDINAMINE 6-BROMO-PYRIDIN-3-YLAMINE 6-Bromo-[3]pyridylamine 2-Bromo-5 5-Amino-2-bromopyridine 96% 3-Pyridinamine, 6-bromo- 3-Amino-6-bromopyridine ,97% 5-amine-2-bromopyridin 2-BroMo-5-pyridinaMine 6-BroMo-3-aMinopyridine 3-Amino-6-bromopyridine,98% 5-Amino-2-bromopyridine≥ 98.5% (GC) 5-Amino-2-bromopyridine,97% 3-Amino-6-bromopyridine 97% 5-Amino-2-bromopyridine > 5-Amino-2-bromopyridine ISO 9001：2015 REACH 6-Bromopyridine-3-amine 2-bromo-5-amino pyrdine 13534-97-9 13354-97-9 13594-97-9 Building Blocks Bromopyridines Halopyridines Halogenated Heterocycles Heterocyclic Building Blocks Pyrimidines Pyridines Building Blocks C5 C5 to C6 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Amino-pyridine series C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Chemical Amines Bromopyridines Halopyridines Aromatics Boronic Acid pharmacetical Pyridine series Amines blocks