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(R)-(-)-2-Amino-1-propanol

(R)-(-)-2-Amino-1-propanol structure

CAS No.: 35320-23-1

Chemical Name:: (R)-(-)-2-Amino-1-propanol

Synonyms: (R)-1-Aminopropan-2-ol;D-ALANINOL;(R)-2-AMINO-1-PROPANOL;(2R)-2-AMINO-1-PROPANOL;(2R)-2-Aminopropan-1-ol;D-ALAOH;H-D-ALA-OL;H-D-ALANINOL;2-AMINO PROPANOL;D-Alaninol, ee: 97%

CBNumber:: CB7853542

Molecular Formula:: C3H9NO

Molecular Weight:: 75.11

MDL Number:: MFCD00064413

MOL File:: 35320-23-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-29 08:43:58

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(R)-(-)-2-Amino-1-propanol Properties

Melting point	8 °C
Boiling point	173-176 °C(lit.)
alpha	-17 º (c=neat)
Density	0.965
refractive index	n20/D 1.450(lit.)
Flash point	183 °F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Oily Liquid
pka	12.88±0.10(Predicted)
color	Clear colorless to light yellow
Specific Gravity	0.965
optical activity	[α]19/D 18°, neat
Water Solubility	SOLUBLE
Sensitive	Hygroscopic
BRN	1718866
InChI	1S/C3H9NO/c1-3(4)2-5/h3,5H,2,4H2,1H3/t3-/m1/s1
InChIKey	BKMMTJMQCTUHRP-GSVOUGTGSA-N
SMILES	C[C@@H](N)CO
CAS DataBase Reference	35320-23-1(CAS DataBase Reference)
FDA UNII	770ZI70L3Q
NIST Chemistry Reference	(R)-(-)-2-Amino-1-propanol(35320-23-1)
UNSPSC Code	12352116
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

C,Xi

Risk Statements

34-36/37/38

Safety Statements

26-36/37/39-45-36

RIDADR

UN 2735 8/PG 2

WGK Germany

10-23

Hazard Note

Corrosive/Hygroscopic

HazardClass

PackingGroup

III

HS Code

29221990

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Eye Dam. 1
Skin Corr. 1B

Limited Quantities

1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	2
3		0

(R)-(-)-2-Amino-1-propanol price More Price(89)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	297682	(R)-(?)-2-Amino-1-propanol 98%	35320-23-1	1g	$25.92	2024-03-01	Buy
Sigma-Aldrich	297682	(R)-(?)-2-Amino-1-propanol 98%	35320-23-1	5g	$132	2023-06-20	Buy
TCI Chemical	A2002	(R)-(-)-2-Amino-1-propanol >98.0%(GC)(T)	35320-23-1	5mL	$51	2026-04-30	Buy
TCI Chemical	A2002	(R)-(-)-2-Amino-1-propanol >98.0%(GC)(T)	35320-23-1	25mL	$176	2026-04-30	Buy
Usbiological	260572	D-Alaninol Asreported	35320-23-1	25g	$350	2026-06-03	Buy

Product number	Packaging	Price	Buy
297682	1g	$25.92	Buy
297682	5g	$132	Buy
A2002	5mL	$51	Buy
A2002	25mL	$176	Buy
260572	25g	$350	Buy

(R)-(-)-2-Amino-1-propanol Chemical Properties, Uses, Production

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-2-Amino-1-propanol has been used as a derivatizing agent for gossypol during the analysis of gossypol enantiomers in cottonseed by high-performance liquid chromatography.

Application

R)-(-)-2-Amino-1-propanol is used as a chiral intermediate for the synthesis of pharmaceutical products and agrochemicals. It acts as additives in health care products and animal feed. It is a amino alcohol obtained by reduction of d-alanine. This compound could be converted into the corresponding nonracemic adenine derivative (R)-9-(1-Methyl-2-hydroxyethyl)adenine through minor variations on the classic Montgomery sequence[1].
(R)-(-)-2-Amino-1-propanol

General Description

(R)-(-)-2-Amino-1-propanol is a chiral secondary amine.

Synthesis

338-69-2

35320-23-1

General procedure for the synthesis of (R)-2-aminopropan-1-ol from D-alanine: The present embodiment relates to the synthesis of a class of intermediates of long-chain ethylpiperazine sulfonamide derivatives, in particular the preparation of (R)-2-aminopropan-1-ol. 150 mL of anhydrous THF and 1.1 g of LiAlH4 (29 mmol) were added to a dry three-necked flask and the reaction system was cooled to 0 °C. Subsequently, 4.9 g of D-alanine (55.0 mmol) was added to the reactor in batches, and the addition process lasted for 30 min. After the addition was completed, stirring was continued at 0 °C for 2 h. Then the temperature was gradually increased to reflux and the reflux reaction was maintained for 16 h. The reaction system was then cooled to 0 °C for 2 h. Upon completion of the reaction, the reaction system was cooled in an ice bath, and 100 mL of ether, 4.5 mL of water, 4.5 mL of 15% NaOH solution, and 12 mL of water were added slowly in sequence to quench the reaction. The reaction mixture was filtered through diatomaceous earth and the filtrate was collected. The filtrate was concentrated under reduced pressure to remove the solvent to give the crude product. The crude product was purified by silica gel column chromatography with the eluent of dichloromethane:ethanol=10:1 (v/v), resulting in 3.41 g of colorless oily product in 82.5% yield.

References

[1] Jeffery A, et al. Synthesis of Acyclic Nucleoside and Nucleotide Analogues from Amino Acids: A Convenient Approach to a PMEA±PMPA Hybrid. Tetrahedron, 2000; 56: 5077-5083.

(R)-(-)-2-Amino-1-propanol Preparation Products And Raw materials

Raw materials

methyl DL-alaninate D-Alanine Propylene glycol Lithium Aluminum Hydride Tetrahydrofuran

Preparation Products

Carbamic acid, N-[(1R)-2-hydroxy-1-methylethyl]-, 2-propen-1-yl ester N-(2-Hydroxy-1r-methylethyl)-hexadecanamide

(R)-(-)-2-Amino-1-propanol Suppliers

Global Suppliers ( 559)

Supplier	Tel	Email	Country	ProdList	Advantage
Xi'an Qingxiang Biotechnology Co., Ltd	029-18192656670 18192656670	2557411153@qq.com	China	189	58
Jiangxi Kingnord Industrial Limited	0791-86493591	jeff@kingnord.com	China	43	57
Aikon International Limited	025-58851090 13913916777	sales01@aikonchem.com	China	15947	58
Shanghai Pin Research Chemical Co., Ltd.	15900489257	271793832@qq.com	China	37	58
Shanghai CanSpecsci Instrument Co., Ltd.	400-6087598 15021221957	order@canspecsci.com	China	2001	56
Xi 'an billiton biological technology co., LTD	029-88764766	wang.yali@xatuochao.com	China	522	58
XIANAONARUNNEWMATERIALCo.,Ltd	029-81509060 13629280593	2074901304@qq.com	China	185	58
Tianjin Xinkangyou Biotechnology Co., LTD	19922659386 19922659386	3753493636@qq.com	China	847	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62

Supplier	Advantage
Xi'an Qingxiang Biotechnology Co., Ltd	58
Jiangxi Kingnord Industrial Limited	57
Aikon International Limited	58
Shanghai Pin Research Chemical Co., Ltd.	58
Shanghai CanSpecsci Instrument Co., Ltd.	56
Xi 'an billiton biological technology co., LTD	58
XIANAONARUNNEWMATERIALCo.,Ltd	58
Tianjin Xinkangyou Biotechnology Co., LTD	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62

Application research of (D)-2-alaninol
(D)-2-Alaninol is one of the raw materials for synthesizing the ofloxacin. This article will introduce other application resea....
Jul 24,2025

View Latest Price from (R)-(-)-2-Amino-1-propanol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	(R)-(-)-2-Amino-1-propanol 35320-23-1	$1.20-34.00	1kg	99%		Henan Fengda Chemical Co., Ltd
2026-07-29	(R)-(-)-2-Amino-1-propanol 35320-23-1		1kg	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd
2026-03-20	(R)-(-)-2-Amino-1-propanol 35320-23-1	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

(R)-(-)-2-Amino-1-propanol
35320-23-1
$1.20-34.00
99%
Henan Fengda Chemical Co., Ltd

(R)-(-)-2-Amino-1-propanol
35320-23-1
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

(R)-(-)-2-Amino-1-propanol
35320-23-1
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

(R)-(-)-2-Amino-1-propanol Spectrum

(R)-(-)-2-Amino-1-propanol(35320-23-1)MS (R)-(-)-2-Amino-1-propanol(35320-23-1)¹HNMR (R)-(-)-2-Amino-1-propanol(35320-23-1)¹³CNMR (R)-(-)-2-Amino-1-propanol(35320-23-1)IR1 (R)-(-)-2-Amino-1-propanol(35320-23-1)Raman

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D-Alaninol, 98%, ee: 98% (R)-(-)-2-AMINOPROPANOL (R)-(-)-2-AMINO-1-PROPANOL H-DL-ALA-OL D-ALAOH D-(-)-ALANINOL D-2-AMINO-PROPANOL D - aMino propanol (R)-(-)-2-Amino-1-propanol (R)-(-)-2-AMino-1-propanol 98% (R)-(-)-2-AMino-1-propanol, 99.8%+ D-Alaninol≥ 99% (GC) (2R)-2-AMINO-1-PROPANOL (+/-)-2-AMINO-1-PROPANOL 2-AMINO PROPANOL DL-2-AMINOPROPYL-ALCOHOL DL-2-AMINO PROPANOL DL-ALANILOL D-ALANINOL / (R)-(-)-2-AMINO-1-PROPANOL D-amine propionic acid D-Alaniol-(R)-(-)-2-Amino-1-Propanol D-Alaniol R(-)-2-AMINO-1-PROPANOL-13C3 (D-ALANINOL D-Alaninol98% D-Ala-ol 1-PROPANOL, 2-AMINO-, (2R)- D-Alaninol ,98% [ee: 97%] D-Alanilol (2R)-2-Amino-1-hydroxypropane, D-Alaninol [(R)-1-Methyl-2-hydroxyethyl]amine (R)-(-)-2-Amino-1-propanol,98% (R)-(-)-2-Amino-1-propanol > (R)-(-)-2-Amino-1-propanol USP/EP/BP D-Alaninol, 98% [(R)-(-)-2-Amino-1-propanol] (D)-2-Alaninol H-D-ALA-OL H-D-ALANINOL (2R)-2-Aminopropan-1-ol (R)-2-AMINO-1-PROPANOL (R)-1-Aminopropan-2-ol D-Alaninol, ee: 97% D-ALANINOL D-Alaninol (D-2-Aminopropan-1-ol) 35320-23-1 5320-23-1 CH3CHNH2CH2OH AMINE Amino Alcohols Alphabetical Listings Amino Acid Derivatives BioChemical Asymmetric Synthesis Chiral Building Blocks Specialty Synthesis Peptide Synthesis Stable Isotopes Organic Building Blocks Alanine [Ala, A]