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Isobutyric anhydride

CAS No.
97-72-3
Chemical Name:
Isobutyric anhydride
Synonyms
Isobutylic anhydride;Isobutyric acid anhydride;2-METHYLPROPANOIC ANHYDRIDE;Isobutyric anhydride, distilled;(iso-C3H7CO)2O;isobutyryloxide;Isobutyl Anhydride;sobutyric anhydride;isobutyrylanhydride;ISOBUTRIC ANHYDRIDE
CBNumber:
CB7854736
Molecular Formula:
C8H14O3
Molecular Weight:
158.2
MDL Number:
MFCD00008913
MOL File:
97-72-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:25:30
Product description Number Pack Size Price
Isobutyric anhydride 97% 245771 25ml $33.4
Isobutyric anhydride 97% 245771 2l $167
Isobutyric Anhydride >95.0%(GC)(T) I0111 25mL $25
Isobutyric Anhydride >95.0%(GC)(T) I0111 500mL $61
Isobutyric anhydride 97% 245771 500ml $57.2
More product size

Isobutyric anhydride Properties

Melting point -56 °C (lit.)
Boiling point 182 °C (lit.)
Density 0.954 g/mL at 25 °C (lit.)
vapor density 5.45 (vs air)
vapor pressure 10 mm Hg ( 67 °C)
refractive index n20/D 1.406(lit.)
Flash point 152 °F
storage temp. Store below +30°C.
form Liquid
color Clear colorless
explosive limit 1.09%, 87°F
Water Solubility decomposes
Sensitive Moisture Sensitive
BRN 386267
Dielectric constant 13.9(20℃)
Exposure limits ACGIH: TWA 10 ppm
NIOSH: TWA 10 ppm(30 mg/m3); STEL 15 ppm(45 mg/m3)
InChI 1S/C8H14O3/c1-5(2)7(9)11-8(10)6(3)4/h5-6H,1-4H3
InChIKey LSACYLWPPQLVSM-UHFFFAOYSA-N
SMILES CC(C)C(=O)OC(=O)C(C)C
LogP 1.1 at 25℃
CAS DataBase Reference 97-72-3(CAS DataBase Reference)
FDA UNII N85A80FJDT
NIST Chemistry Reference Propanoic acid, 2-methyl-, anhydride(97-72-3)
EPA Substance Registry System Isobutyric anhydride (97-72-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06
Signal word  Danger
Hazard statements  H301+H311-H314
Precautionary statements  P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P361+P364
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  34-21/22
Safety Statements  26-36/37/39-45
RIDADR  2922
WGK Germany  3
RTECS  NQ5550000
13-21
Autoignition Temperature 624 °F
TSCA  TSCA listed
HS Code  2915 90 70
HazardClass  8
PackingGroup  II
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Oral
Skin Corr. 1B
Hazardous Substances Data 97-72-3(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 266 mg/kg LD50 dermal Rabbit 475 mg/kg
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
3 1

Isobutyric anhydride price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 245771 Isobutyric anhydride 97% 97-72-3 25ml $33.4 2026-03-19 Buy
Sigma-Aldrich 245771 Isobutyric anhydride 97% 97-72-3 2l $167 2026-03-19 Buy
TCI Chemical I0111 Isobutyric Anhydride >95.0%(GC)(T) 97-72-3 25mL $25 2026-03-19 Buy
TCI Chemical I0111 Isobutyric Anhydride >95.0%(GC)(T) 97-72-3 500mL $61 2026-03-19 Buy
Sigma-Aldrich 245771 Isobutyric anhydride 97% 97-72-3 500ml $57.2 2026-03-19 Buy
Product number Packaging Price Buy
245771 25ml $33.4 Buy
245771 2l $167 Buy
I0111 25mL $25 Buy
I0111 500mL $61 Buy
245771 500ml $57.2 Buy

Isobutyric anhydride Chemical Properties,Uses,Production

Chemical Properties

clear colorless liquid

Uses

Isobutyric anhydride was used in the synthesis of 4-O-isobutyryl derivative via reaction with octyl β-D-glucopyranoside in the presence of C2-symmetric chiral 4-pyrrolidinopyridine as a catalyst.

Preparation

Isobutyric anhydride is prepared from iso-Butyryl chloride and Sodium acetate, or: from iso-Butyryl chloride and Butyric acid with a catalyst.

Definition

ChEBI: An acyclic carboxylic anhydride of isobutyric acid. Metabolite observed in cancer metabolism.

General Description

Isobutyric anhydride is a colorless liquid. Flash point 139°F. Burns skin and eyes. Vapors are heavier than air.

Air & Water Reactions

Flammable. Reacts exothermically with water or moisture-containing materials to form isobutyric acid.

Reactivity Profile

Isobutyric anhydride reacts exothermically with water. The reactions are sometimes slow, but can become violent when local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with a cids, strong oxidizing agents, alcohols, amines, and bases.

Hazard

Strong irritant to tissue.

Health Hazard

Isobutyric anhydride may cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Global( 270)Suppliers
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Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5235 58
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+8615255079626 eric@witopchemical.com China 23541 58
Alfa Chemistry
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View Lastest Price from Isobutyric anhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isobutyric anhydride pictures 2026-03-20 Isobutyric anhydride
97-72-3
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
Isobutyric Anhydride Anib pictures 2025-05-26 Isobutyric Anhydride Anib
97-72-3
US $0.00 / KG 1KG 99.5% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
Isobutyric anhydride pictures 2023-05-04 Isobutyric anhydride
97-72-3
US $48.00-40.00 / KG 1KG 99% 200tons Guangzhou Sunton Biotechnology Co., Ltd.
Isobutyric anhydride, distilled #niso-Butyric anhydride Bis(2-methylpropanoic)anhydride Bis(2-methylpropionic)anhydride Bis(isobutyric)anhydride Di(isobutyric acid)anhydride Diisobutyric anhydride (iso-C3H7CO)2O 1-Methylpropanoic anhydride 2-Methylpropanoic acid anhydride 2-methyl-propanoicacianhydride 2-methylpropanoicacidanhydride anhydrideisobutyrique Isobutryic anhydride Isobutyric acid anhydride isobutyricacidanhydride Isobutyryl anhydride Isobutylic anhydride Isobutyric anhydride,97% Isobutyl Anhydride Isobutyric anhydride, 97% 2KG Isobutyric anhydride, 97% 500GR ISOBUTYRIC ANHYDRIDE FOR SYNTHESIS Propanoic acid,2-Methyl-, 1,1'-anhydride Isobutyric Anhydride, 95.0%(GC&T Isobutyric anhydride 97% sobutyric anhydride isobutyrylanhydride isobutyryloxide Propanoicacid,2-methyl-,anhydride 2-METHYLPROPIONIC ANHYDRIDE 2-METHYLPROPANOIC ANHYDRIDE ALPHA-METHYLPROPIONIC ANHYDRIDE A-METHYLPROPIONIC ANHYDRIDE DIMETHYLACETIC ANHYDRIDE ISOBUTYRIC ANHYDRIDE BIS(2-METHYLPROPIONIC ACID) ANHYDRIDE IsobutyricAnhydride> Isobutyric Anhydride Anib ISOBUTRIC ANHYDRIDE 97-72-3 25ML/瓶[97-72-3 CH32CHCO2O CH32CHCO2COCHCH32 Building Blocks Carboxylic Acid Anhydrides Carbonyl Compounds Organic Building Blocks Organics 1 bc0001