1-(4-Chlorophenyl)-2-methyl-2-propanol
- CAS No.
- 5468-97-3
- Chemical Name:
- 1-(4-Chlorophenyl)-2-methyl-2-propanol
- Synonyms
- 1-(4-chlorophenyl)-2-methylpropan-2-ol;2-(4-Chlorobenzyl)-2-propanol;4-Chloro-α,α-dimethylbenzeneethanol;4-Chloro-α,α-dimethylphenethyl alcohol;1-(4-CHLOROPHENYL)-2-METHYL-2-PROPANOL;2-(4-Chlorophenyl)-1,1-diMethylethanol;1-(4-chlorophenyl)-2-methyl-propan-2-ol;4-chloro-α,α-dimethylphenethylic alcohol;4-chloro-alpha,alpha-dimethylphenethylic alcohol;1-(4-Chlorophenyl)-2-methylpropan-2-ol, 1-(Chlorophenyl)-2-hydroxy-2-methylpropane
- CBNumber:
- CB7926619
- Molecular Formula:
- C10H13ClO
- Molecular Weight:
- 184.66
- MDL Number:
- MFCD00004466
- MOL File:
- 5468-97-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-alpha,alpha-dimethylphenethyl alcohol 96% | OR61252 | 250mg | $78 |
| 1-(4-Chlorophenyl)-2-methylpropan-2-ol 96% | AS47721 | 1g | $229 |
| 4-Chloro-alpha,alpha-dimethylphenethyl alcohol 96% | OR61252 | 1g | $160 |
| 1-(4-Chlorophenyl)-2-methylpropan-2-ol 96% | AS47721 | 5g | $685 |
| 1-(4-Chlorophenyl)-2-methylpropan-2-ol 96% | C53019 | 250mg | $150 |
| More product size | |||
| Melting point | 34°C |
|---|---|
| Boiling point | 263.92°C (rough estimate) |
| Density | 1.0639 (rough estimate) |
| refractive index | 1.5310 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DCM |
| form | Oil |
| color | Orange |
| FDA UNII | KK2S3BZ6WD |
| NIST Chemistry Reference | P-chloro-«alpha»,«alpha»-dimethylphenethyl alcohol(5468-97-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501 |
| HS Code | 2907290090 |
1-(4-Chlorophenyl)-2-methyl-2-propanol price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR61252 | 4-Chloro-alpha,alpha-dimethylphenethyl alcohol 96% | 5468-97-3 | 250mg | $78 | 2026-06-04 | Buy |
| Activate Scientific | AS47721 | 1-(4-Chlorophenyl)-2-methylpropan-2-ol 96% | 5468-97-3 | 1g | $229 | 2026-06-04 | Buy |
| Apolloscientific | OR61252 | 4-Chloro-alpha,alpha-dimethylphenethyl alcohol 96% | 5468-97-3 | 1g | $160 | 2026-06-04 | Buy |
| Activate Scientific | AS47721 | 1-(4-Chlorophenyl)-2-methylpropan-2-ol 96% | 5468-97-3 | 5g | $685 | 2026-06-04 | Buy |
| Synthonix | C53019 | 1-(4-Chlorophenyl)-2-methylpropan-2-ol 96% | 5468-97-3 | 250mg | $150 | 2026-05-06 | Buy |
1-(4-Chlorophenyl)-2-methyl-2-propanol Chemical Properties,Uses,Production
Uses
2-(4-Chlorophenyl)-1,1-dimethylethanol is an intermediate in the synthesis of Chlorphentermine (C375080), anorectic agent that is structurally related to amphetamine.
Synthesis
104-83-6
5468-97-3
Example 1: Synthesis of 1-(4-chlorophenyl)-2-methyl-2-propanol 1. In a three-necked flask equipped with a stirrer and reflux condenser, a solution of 4-chlorobenzyl chloride (165 g, 1.02 mol) in ether (500 ml) was added. 2. Magnesium flakes (24.3 g, 1.00 mol) were added slowly and dropwise over a period of 1 h. The reaction mixture began to reflux spontaneously. 3. After continuing to reflux for 1 hr, the reaction solution was cooled to room temperature. 4. 4. add acetone (60.0 g, 1.30 mol) dropwise to the reaction mixture. 5. Heat the reaction mixture to reflux for 3 hours. 6. 6. Upon completion of the reaction, the reaction mixture was cooled and poured into a mixture of ice (500 ml) and concentrated hydrochloric acid (92 ml). 7. Separate the organic and aqueous phases. 8. The organic phase was washed with water and subsequently dried with anhydrous sodium sulfate. 9. The solvent was removed by vacuum evaporation to give the crude product. 10. The crude product was purified by fractional distillation and the fractions with a boiling point of 123°-124 °C/12 mmHg were collected to give 1-(4-chlorophenyl)-2-methyl-2-propanol (nD25 = 1.5300; 128.5 g, 70% yield).
References
[1] Patent: US4237311, 1980, A
1-(4-Chlorophenyl)-2-methyl-2-propanol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dalian Richfortune Chemicals Co., Ltd | +86-86-411-84820922 +86-8613904096939 | sales@richfortunechem.com | China | 305 | 57 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 6085 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from 1-(4-Chlorophenyl)-2-methyl-2-propanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 1-(4-Chlorophenyl)-2-methyl-2-propanol
5468-97-3
|
$1.00 | 1KG | 98%HPLC | 10tons | Career Henan Chemical Co |
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- 1-(4-Chlorophenyl)-2-methyl-2-propanol
5468-97-3
- $1.00
- 98%HPLC
- Career Henan Chemical Co
