valnoctamide
- CAS No.
- 4171-13-5
- Chemical Name:
- valnoctamide
- Synonyms
- Axiquel;Nirvani;Nirvanil;McN-X-181;NSC-32363;valnoctamide;Valmethamide;2-Ethyl-3-methylvaleramide;2-Ethyl-3-methylpentan-amide;Pentanamide, 2-ethyl-3-methyl-
- CBNumber:
- CB7931541
- Molecular Formula:
- C8H17NO
- Molecular Weight:
- 143.23
- MDL Number:
- MFCD00868184
- MOL File:
- 4171-13-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Valnoctamide ≥98% (NMR) | V4765 | 5mg | $83.2 |
| Valnoctamide ≥98% (NMR) | V4765 | 25mg | $319 |
| Valnoctamide ≥95% | 18456 | 5mg | $32 |
| Valnoctamide ≥95% | 18456 | 10mg | $55 |
| Valnoctamide ≥95% | 18456 | 25mg | $93 |
| Melting point | 113.5-1140C |
|---|---|
| Boiling point | 261.35°C (rough estimate) |
| Density | 0.9636 (rough estimate) |
| refractive index | 1.4614 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMSO: soluble20mg/mL, clear |
| pka | 16.81±0.50(Predicted) |
| form | powder |
| color | white to off-white |
| Water Solubility | 8.70g/L(temperature not stated) |
| InChI | 1S/C8H17NO/c1-4-6(3)7(5-2)8(9)10/h6-7H,4-5H2,1-3H3,(H2,9,10) |
| InChIKey | QRCJOCOSPZMDJY-UHFFFAOYSA-N |
| SMILES | CCC(C)C(CC)C(N)=O |
| FDA UNII | 3O25NRX9YG |
| ATC code | N05CM13 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YV5950000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| Toxicity | LD50 oral in rat: 760mg/kg | |||||||||
| NFPA 704 |
|
valnoctamide price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | V4765 | Valnoctamide ≥98% (NMR) | 4171-13-5 | 5mg | $83.2 | 2026-03-19 | Buy |
| Sigma-Aldrich | V4765 | Valnoctamide ≥98% (NMR) | 4171-13-5 | 25mg | $319 | 2026-03-19 | Buy |
| Cayman Chemical | 18456 | Valnoctamide ≥95% | 4171-13-5 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 18456 | Valnoctamide ≥95% | 4171-13-5 | 10mg | $55 | 2024-03-01 | Buy |
| Cayman Chemical | 18456 | Valnoctamide ≥95% | 4171-13-5 | 25mg | $93 | 2024-03-01 | Buy |
valnoctamide Chemical Properties,Uses,Production
Description
Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain. Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity. It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM). Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.
Chemical Properties
Crystalline Solid
Uses
Isomer of Valpromide. Anxiolytic.
Definition
ChEBI: Valnoctamide is a fatty amide.
brand name
Axiquel (Ortho-McNeil).
References
[1] ROGAWSKI M A. Diverse mechanisms of antiepileptic drugs in the development pipeline[J]. Epilepsy Research, 2006, 69 3: Pages 273-294. DOI: 10.1016/j.eplepsyres.2006.02.004
[2] ILAN WINKLER. Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain[J]. British Journal of Pharmacology, 2009, 146 2: 198-208. DOI: 10.1038/sj.bjp.0706310
[3] GALIT SHALTIEL. Effect of valproate derivatives on human brain myo-inositol-1-phosphate (MIP) synthase activity and amphetamine-induced rearing.[J]. Pharmacological Reports, 2007, 59 4: 402-407.
[4] JAY SPAMPANATO F. E D. Valnoctamide enhances phasic inhibition: A potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus[J]. Epilepsia, 2014, 55 9: e94-e98. DOI: 10.1111/epi.12702
valnoctamide Preparation Products And Raw materials
Raw materials
Preparation Products
valnoctamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +8617392712697 | 1022@dideu.com | China | 8401 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53802 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57422 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
View Lastest Price from valnoctamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | Valnoctamide
4171-13-5
|
US $29.00 / mg | 98.00% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-12-27 | valnoctamide
4171-13-5
|
US $1.00 / KG | 1KG | 97%-99.9% | 100kg | Career Henan Chemical Co |
-
- Valnoctamide
4171-13-5
- US $29.00 / mg
- 98.00%
- TargetMol Chemicals Inc.
-
- valnoctamide
4171-13-5
- US $1.00 / KG
- 97%-99.9%
- Career Henan Chemical Co
