5-Fluoro-3-iodo-1H-indazole
- CAS No.
- 858629-06-8
- Chemical Name:
- 5-Fluoro-3-iodo-1H-indazole
- Synonyms
- 5-Fluoro-3-iodo-1H-indazole;5-fluoro-3-iodo-2H-indazole;1H-INDAZOLE,5-FLUORO-3-IODO-;5-FLUORO-3-IODO-1H-INDAZOLE 98%;5-fluoro-3-iodo-1H-indazole(SALTDATA: FREE)
- CBNumber:
- CB7970672
- Molecular Formula:
- C7H4FIN2
- Molecular Weight:
- 262.02
- MDL Number:
- MFCD06739145
- MOL File:
- 858629-06-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Fluoro-3-iodo-1H-indazole | B435018 | 100mg | $75 |
| 5-Fluoro-3-iodo-1H-indazole | L822 | 1g | $96 |
| 5-FLUORO-3-IODO-1H-INDAZOLE 95.00% | HCH0013607 | 5G | $1672.44 |
| 5-Fluoro-3-iodo-1H-indazole 97% | PC8399 | 1g | $16 |
| 5-Fluoro-3-iodo-1H-indazole 97% | 3H32-K-X6 | 1g | $32 |
| Boiling point | 361.4±22.0 °C(Predicted) |
|---|---|
| Density | 2.158±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 10.94±0.40(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | InChI=1S/C7H4FIN2/c8-4-1-2-6-5(3-4)7(9)11-10-6/h1-3H,(H,10,11) |
| InChIKey | CZUPBTJBMHZBTJ-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(F)C=C2)C(I)=N1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
5-Fluoro-3-iodo-1H-indazole price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B435018 | 5-Fluoro-3-iodo-1H-indazole | 858629-06-8 | 100mg | $75 | 2021-12-16 | Buy |
| AK Scientific | L822 | 5-Fluoro-3-iodo-1H-indazole | 858629-06-8 | 1g | $96 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0013607 | 5-FLUORO-3-IODO-1H-INDAZOLE 95.00% | 858629-06-8 | 5G | $1672.44 | 2021-12-16 | Buy |
| Apolloscientific | PC8399 | 5-Fluoro-3-iodo-1H-indazole 97% | 858629-06-8 | 1g | $16 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3H32-K-X6 | 5-Fluoro-3-iodo-1H-indazole 97% | 858629-06-8 | 1g | $32 | 2021-12-16 | Buy |
5-Fluoro-3-iodo-1H-indazole Chemical Properties,Uses,Production
Synthesis
348-26-5
858629-06-8
5-Fluoro-1H-indazole (2.0 g, 14.0 mmol) was used as raw material and dissolved in DIVIF (50 mL). To this solution, iodine (7.46 g, 28.0 mmol) and potassium hydroxide (2.4 g, 42 mmol) were added sequentially at 0 °C. The reaction mixture was stirred at 0 °C for 0.5 h and then gradually warmed up to room temperature. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was filtered and the filtrate was concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=3/1) to afford 5-fluoro-3-iodo-1H-indazole (3.7 g, yield: 96.1%) as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ=13.64 (s, 1H), 7.63 (dd, J=4.8,4.4 Hz, 1H), 7.38-7.30 (m, 1H), 7.20 (dd, J=6.4,2.4 Hz, 1H).
References
[1] Patent: WO2018/132372, 2018, A1. Location in patent: Paragraph 01229
[2] Patent: WO2018/188590, 2018, A1. Location in patent: Paragraph 00437
[3] Synthesis, 2011, # 19, p. 3089 - 3098
[4] Journal of Medicinal Chemistry, 2014, vol. 57, # 12, p. 5419 - 5434
[5] Molecules, 2018, vol. 23, # 8,
5-Fluoro-3-iodo-1H-indazole Preparation Products And Raw materials
Raw materials
Preparation Products
5-Fluoro-3-iodo-1H-indazole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
View Lastest Price from 5-Fluoro-3-iodo-1H-indazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-14 | 5-Fluoro-3-iodo-1H-indazole
858629-06-8
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
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- 5-Fluoro-3-iodo-1H-indazole
858629-06-8
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
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