(+)-PINORESINOL
- CAS No.
- 487-36-5
- Chemical Name:
- (+)-PINORESINOL
- Synonyms
- 80% ee);(+)-Piresil;(+)-PINORESINOL;(+/-)-Pinoresinol;(+)-Pinoresinol-RM;(+)-Pinoresinol (>(+)-Pinoresinol (>80% ee);Pinoresinol, 10 mM in DMSO;(+)-Pinoresinol,Pinoresinol;(1β,5β)-2β,6β-Bis(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
- CBNumber:
- CB8100858
- Molecular Formula:
- C20H22O6
- Molecular Weight:
- 358.39
- MDL Number:
- MFCD07784516
- MOL File:
- 487-36-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Pinoresinol ≥95.0% (HPLC) | 40674 | 10mg | $431 |
| Pinoresinol analyticalstandard | 06709 | 10mg | $650 |
| (+)-Pinoresinol min. 98.0 % | P2568 | 5MG | $97 |
| (+)-Pinoresinol min. 98.0 % | P2568 | 25MG | $290 |
| (+)-Pinoresinol | 27700 | 5mg | $57 |
| More product size | |||
| Melting point | 112 °C |
|---|---|
| Boiling point | 556.5±50.0 °C(Predicted) |
| Density | 1.385 g/cm3 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: ≥6mg/mL |
| pka | 9.54±0.35(Predicted) |
| form | Solid |
| color | white to tan |
| Major Application |
cleaning products cosmetics food and beverages personal care |
| InChI | InChI=1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1 |
| InChIKey | HGXBRUKMWQGOIE-AFHBHXEDSA-N |
| SMILES | O1C[C@]2([H])[C@@H](C3=CC=C(O)C(OC)=C3)OC[C@]2([H])[C@H]1C1=CC=C(O)C(OC)=C1 |
| LogP | 1.591 (est) |
| FDA UNII | V4N1UDY811 |
| UNSPSC Code | 85151701 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
(+)-PINORESINOL price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 40674 | Pinoresinol ≥95.0% (HPLC) | 487-36-5 | 10mg | $431 | 2025-07-31 | Buy |
| Sigma-Aldrich | 06709 | Pinoresinol analyticalstandard | 487-36-5 | 10mg | $650 | 2025-07-31 | Buy |
| TCI Chemical | P2568 | (+)-Pinoresinol min. 98.0 % | 487-36-5 | 5MG | $97 | 2025-07-31 | Buy |
| TCI Chemical | P2568 | (+)-Pinoresinol min. 98.0 % | 487-36-5 | 25MG | $290 | 2025-07-31 | Buy |
| Cayman Chemical | 27700 | (+)-Pinoresinol | 487-36-5 | 5mg | $57 | 2024-03-01 | Buy |
(+)-PINORESINOL Chemical Properties,Uses,Production
Description
(+)-Pinoresinol is a lignan that has been found in Forsythia and virgin olive oils and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an inhibitor of α-glucosidase and maltase (IC50s = 492 and 34.3 μM in Baker’s yeast and rat small intestine, respectively). (+)-Pinoresinol scavenges ABTS , but not 2,2-diphenyl-1-picrylhydrazyl (DPPH; ), radicals in cell-free assays (IC50s = 13.43 and >200 μg/ml, respectively). It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37, cells with IC50 values of 29.35, 62.35, 75.32, >80, and >80 μM, respectively. (+)-Pinoresinol prevents cell death induced by glutamate in HT22 cells (EC50 = 6.96 μM) and inhibits LPS-induced nitric oxide production in RAW 264.7 cells (IC50 = 7.89 μM).
Uses
(+)-Pinoresinol is a lignan found in olive oil and in other plants. This phenolic compound was reported to have antioxidant and anticancer potential.
Definition
ChEBI: An enantiomer of pinoresinol having (+)-1S,3aR,4S,6aR-configuration.
References
[1] ALICIA LóPEZ-BIEDMA . The biological activities of natural lignans from olives and virgin olive oils: A review[J]. Journal of Functional Foods, 2016, 26: Pages 36-47. DOI: 10.1016/j.jff.2016.07.005
[2] DAN-QI LI. Antioxidant and cytotoxic lignans from the roots of Bupleurum chinense[J]. Journal of Asian Natural Products Research, 2017, 19 1: 519-527. DOI: 10.1080/10286020.2016.1234456
[3] ARIN WIKUL . (+)-Pinoresinol is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds though inhibiting α-glucosidase[J]. Bioorganic & Medicinal Chemistry Letters, 2012, 22 16: Pages 5215-5217. DOI: 10.1016/j.bmcl.2012.06.068
[4] SEO-JI IN. Lignans and neolignans from the stems of Vibrunum erosum and their neuroprotective and anti-inflammatory activity[J]. Archives of Pharmacal Research, 2014, 38 1: 26-34. DOI: 10.1007/s12272-014-0358-9
(+)-PINORESINOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 954 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
View Lastest Price from (+)-PINORESINOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-02 | Pinoresinol
487-36-5
|
US $52.00-197.00 / mg | 98.67% | 10g | TargetMol Chemicals Inc. | ||
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2023-02-24 | Pinoresinol
487-36-5
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2020-02-18 | (+)-PINORESINOL
487-36-5
|
US $8.00 / KG | 1KG | >98% HPLC | 20 tons | Career Henan Chemical Co |
-

- Pinoresinol
487-36-5
- US $52.00-197.00 / mg
- 98.67%
- TargetMol Chemicals Inc.
-

- Pinoresinol
487-36-5
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-

- (+)-PINORESINOL
487-36-5
- US $8.00 / KG
- >98% HPLC
- Career Henan Chemical Co
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