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Zinc acetate

CAS No.
557-34-6
Chemical Name:
Zinc acetate
Synonyms
Zn(OAc)2;Zinc diacetate;Galzin;NA-9153;ai3-04465;siltexcl4;ZINC ACETATE;Diacetoxyzinc;zincdiacetate;ZincAcetateBp
CBNumber:
CB8108591
Molecular Formula:
C4H6O4Zn
Molecular Weight:
183.48
MDL Number:
MFCD00012454
MOL File:
557-34-6.mol
MSDS File:
SDS
Last updated:2026-01-26 13:56:28
Product description Number Pack Size Price
Zinc acetate 99.99% trace metals basis 383317 25g $111
Zinc acetate 99.99% trace metals basis 383317 100g $345.92
Zinc acetate 99.99% trace metals basis 383317 500g $1030
Zinc Acetate Z438100 10g $110
Zinc acetate 292143 50g $322
More product size

Zinc acetate Properties

Melting point 83-86 °C
Boiling point 908°C
Density 1.84 g/mL at 25 °C (lit.)
vapor pressure 0.001Pa at 25℃
Flash point 12 °C
storage temp. Inert atmosphere,Room Temperature
solubility Methanol (Slightly), Water (Slightly)
form Powder
pka 4.756[at 20 ℃]
Specific Gravity 1.84
color Yellow to brown to gray-green
Water Solubility Soluble in water, alcohol, dilute mineral acids and alkalies.
Sensitive Hygroscopic
Merck 14,10128
Cosmetics Ingredients Functions ORAL CARE
ANTIMICROBIAL
SKIN PROTECTING
ASTRINGENT
InChI 1S/2C2H4O2.Zn/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
InChIKey DJWUNCQRNNEAKC-UHFFFAOYSA-L
SMILES CC(O[Zn]OC(C)=O)=O
LogP -1.28
FDA 21 CFR 175.105; 310.545; 582.80
CAS DataBase Reference 557-34-6(CAS DataBase Reference)
SCOGS (Select Committee on GRAS Substances) Zinc acetate
Substances Added to Food (formerly EAFUS) ZINC ACETATE
EWG's Food Scores 3-4
FDA UNII H2ZEY72PME
ATC code A16AX05
NIST Chemistry Reference Zinc acetate(557-34-6)
EPA Substance Registry System Zinc acetate (557-34-6)
UNSPSC Code 12352103
NACRES NA.82

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H318-H411
Precautionary statements  P264-P270-P273-P280-P301+P312-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,N,Xi,F
Risk Statements  36-50/53-22-11
Safety Statements  26-60-61-39-16-7
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  AK1500000
TSCA  TSCA listed
HazardClass  9
HS Code  29152990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Dam. 1
Hazardous Substances Data 557-34-6(Hazardous Substances Data)
NFPA 704
1
3 1

Zinc acetate price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 383317 Zinc acetate 99.99% trace metals basis 557-34-6 25g $111 2025-07-31 Buy
Sigma-Aldrich 383317 Zinc acetate 99.99% trace metals basis 557-34-6 100g $345.92 2025-07-31 Buy
Sigma-Aldrich 383317 Zinc acetate 99.99% trace metals basis 557-34-6 500g $1030 2025-07-31 Buy
TRC Z438100 Zinc Acetate 557-34-6 10g $110 2021-12-16 Buy
Usbiological 292143 Zinc acetate 557-34-6 50g $322 2021-12-16 Buy
Product number Packaging Price Buy
383317 25g $111 Buy
383317 100g $345.92 Buy
383317 500g $1030 Buy
Z438100 10g $110 Buy
292143 50g $322 Buy

Zinc acetate Chemical Properties,Uses,Production

Description

Zinc acetate (chemical formula: Zn(O2CCH3)2) is a kind of salt commonly existing in the dihydrate form. It appears as colorless solid. It is produced through the reaction between zinc oxide with acetate acid. Given that zinc is an essential element for growth and development of human body, zinc acetate can be used as a dietary supplement for the treatment of zinc deficiency. It plays an important role for the synthesis of cholesterol, protein, and fats. It can also be used as an astringent, styptic and emetic. In industry, it has various kinds of applications including wood preservation, manufacturing of other zinc salts as well as ethylene acetate, being used as a dye mordant, and analytical reagent.

Chemical Properties

Zinc acetate occurs as white crystalline, lustrous plates with a faint acetic odor and an astringent taste.

Physical properties

The acetate group is capable of binding to metal ions in a variety of ways through its two oxygen atoms and several connectivities are observed for the various hydrates of zinc acetate. Anhydrous zinc acetate adopts a polymeric structure consisting of zinc coordinated to four oxygen atoms in a tetrahedral environment, each tetrahedron being connected to neighbors by the acetate groups . The acetate ligands are not bidentate. In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.
2 - 5 - Heating pad
Heating Zn(CH3CO2)2 in a vacuum results in loss of acetic anhydride, leaving a residue of ""basic zinc acetate,"" with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ~1.97 vs ~1.63 Å for Be4O(OAc)6.

Uses

Zinc acetate anhydrous is used in the synthesis of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis. It is utilized in the ultrasonic preparation of zinc sulfide nanoparticles coated on silica particles. It is administered orally or parenterally as a nutritional supplement. It finds an application in the field of industries such as wood preservation, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. It also acts as a plating inhibitor on primary water piping.

Preparation

Zinc acetate is prepared by the reaction of acetic acid with zinc oxide followed by crystallization (crystals of dihydrate obtained): ZnO + 2CH3COOH → (CH3COO)2Zn + H2O.

Definition

ChEBI: Zinc acetate is an acetate salt in which the cationic component is zinc(2+). It has a role as an astringent. It is a zinc molecular entity and an acetate salt.

Application

Dietary and medicinal applications
Zinc acetate is used as a dietary supplement and in lozenges used to treat the common cold. Zinc acetate alone is thought to be a more effective treatment than zinc gluconate. Zinc acetate can also be used to treat zinc deficiencies. As an oral daily supplement it is used to inhibit the body's absorption of copper as part of the treatment for Wilson's disease. Zinc acetate is also sold as an astringent in the form of an ointment, a topical lotion; or combined with an antibiotic such as erythromycin for the topical treatment of acne. Furthermore Zinc acetate is commonly sold as a topical anti-itch ointment.
Industrial applications
Industrial applications include wood preserving, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. Zinc acetate is a precursor via a sol-gel route to the transparent semi conductor zinc oxide. Zinc acetate is also used for manufacturing glazers for painting on porcelain; as a reagent in testing for albumin, tannin, phosphate; as cross-linking agents for polymers; in tobacco smoke filters; and as a topical fungicide.

Production Methods

Zinc acetate is synthesized by reacting zinc oxide with glacial acetic acid, with subsequent crystallization, separation by centrifugation, and drying and milling of the crystals. No organic solvents are used during the synthesis.

Flammability and Explosibility

Non flammable

reaction suitability

core: zinc
reagent type: catalyst

Pharmaceutical Applications

Zinc acetate has been used as an excipient in a variety of pharmaceutical formulations including topical gels, lotions, and solutions, and subcutaneous injections. It has also been investigated for use in an oral controlled-release formulation for water-soluble drugs in combination with sodium alginate and xanthan gum.
Therapeutically, zinc acetate has been used in oral capsules for the treatment of Wilson’s disease. Zinc acetate has also been demonstrated to be effective as a spermicide in vaginal contraceptives.

Safety

Zinc acetate is used in topical pharmaceutical formulations and subcutaneous injections, where it is generally regarded as relatively nontoxic and nonirritant when used as an excipient. However, zinc acetate is poisonous by intravenous and intraperitoneal routes; it is also moderately toxic following oral consumption.
Zinc acetate:
LD50 (rat, oral): 2.510 g/kg
LD50 (mouse, IP): 0.057 g/kg

Veterinary Drugs and Treatments

Zinc sulfate is used systemically as a nutritional supplement in a variety of species. Oral zinc acetate has been shown to reduce copper toxicity in susceptible dog breeds (Bedlington Terriers, West Highland White Terriers) with hepatic copper toxicosis. Zinc therapy may also be of benefit in the treatment of hepatic fibrosis in the dog. Zinc sulfate is used topically as an astringent and as a weak antiseptic both for dermatologic and ophthalmic conditions.

storage

Zinc acetate loses water of hydration above 101℃. Zinc acetate should be stored in an airtight container in a cool, dry, place.

Incompatibilities

Zinc acetate is incompatible with oxidizing agents, zinc salts, alkalis and their carbonates, oxalates, phosphates, and sulfides.

Regulatory Status

Included in the FDA Inactive Ingredients Database (SC injections; topical lotions and solutions). Included in medicines licensed in the UK.

References

https://en.wikipedia.org/wiki/Zinc_acetate
https://pubchem.ncbi.nlm.nih.gov/compound/Zinc_acetate_dihydrate#section=GHS-Classification

5970-45-6
64-19-7
557-34-6
Synthesis of Zinc acetate from Zinc acetate dihydrate and Acetic acid
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View Lastest Price from Zinc acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Zinc acetate pictures 2026-02-13 Zinc acetate
557-34-6
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Zinc acetate pictures 2026-01-30 Zinc acetate
557-34-6
US $25.00 / ASSAYS 100ASSAYS 99.5% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
Zinc acetate pictures 2026-01-26 Zinc acetate
557-34-6
US $56.00 / g 10g TargetMol Chemicals Inc.
  • Zinc acetate pictures
  • Zinc acetate
    557-34-6
  • US $0.00 / KG
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Zinc acetate pictures
  • Zinc acetate
    557-34-6
  • US $25.00 / ASSAYS
  • 99.5%
  • Hebei Chuanghai Biotechnology Co., Ltd
Acetic acid, zinc(II) salt aceticacid,zinc(ii)salt ai3-04465 Dicarbomethoxyzinc Zinc acetate, pure, 99% zinc acetate solution Zinkdi(acetat) zinc(+2) cation diacetate Acetic acid zinc salt Galzin Zinc acetate, 99%, pure Bis(acetic acid)zinc salt Bisacetoxyzinc Diacetic acid zinc salt Diacetoxyzinc NA-9153 Zinc Acetate, Anhydrous 99.99% Zinc acetate, pure, 99% 25GR Zinc Acetate, Anhydrous (Metals Basis) Zinc acetate, anhydrous, 99.9+% Zinc acetate 99.99% trace Metals basis Zinc acetate, anhydrous, 99.98% (Metals basis), 99.98% Zn(OAc)2 Acetic acid, zinc salt(2:1) Zinc acetate, anhydrous, 99.95% trace metals basis Zinc Acetate Zn(C2H3O2)2 Food grade zinc acetate Zinc(II) acetate, anhydrous 99.99% Zinc Acetate ( C4H6O4Zn) siltexcl4 Zinc diacetate zinc(ii)acetate Zincacetate,anhydrous zincdiacetate ZINC ACETATE, 99.99% METALS BASIS ZINC ACETATE SOLUTION 1M ZINC ACETATE ANHYDROUS EXTRA PURE 99-102% PHARMACEUTICAL GRADE ZINC ACETATE ANHYDROUS 99.98% (METALS BASIS) ZINC ACETATE ANHYDROUS 99+% ZINC ACETATE ANHYDROUS 99.7% ZincAcetateUsp ZincAcetateBp ZINC ACETATE Zinc acetate, 97.5% Zinc acetate, 99.99% Zinc acetate anhydrate 0.1mol/l Zinc Acetate Solution Zinc acetate, 97.5%, for synthesis 0.01mol/l Zinc Acetate Solution Zinc Acetate,>99.5% zinc aceatate Zinc acetate ISO 9001:2015 REACH Zinc acetate,99% Sulfurized fatty acid ester Zinc Acetate Analytical Volumetric Solution in Water Zinc butyrate Zinc Acetate ChemBeads Zinc Acetate 0.1M, Sterile