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Izilendustat hydrochloride

CAS No.
1303513-80-5
Chemical Name:
Izilendustat hydrochloride
Synonyms
Izilendustat hydrochloride;1-Piperazinecarboxylic acid, 4-[[1-[(4-chlorophenyl)methyl]-1,2-dihydro-3-hydroxy-2-oxo-4-pyridinyl]methyl]-, 1,1-dimethylethyl ester, hydrochloride (1:1)
CBNumber:
CB811014715
Molecular Formula:
Molecular Weight:
470.39
MDL Number:
MOL File:
1303513-80-5.mol
Last updated:2025-04-17 18:22:24

Izilendustat hydrochloride Properties

FDA UNII WBQ36T8XFJ

Izilendustat hydrochloride Chemical Properties,Uses,Production

Uses

Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)[1][2][3].

References

[1] Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1.
[2] Robert Shalwitz, et al. Methods for increasing the stabilization of hypoxia inducible factor-1 alpha. Patent WO2011057112A1.
[3] Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1.

Izilendustat hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Izilendustat hydrochloride Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19939 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 1000 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 26070 58

View Lastest Price from Izilendustat hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Izilendustat hydrochloride pictures 2025-05-01 Izilendustat hydrochloride
1303513-80-5
US $2140.00-2785.00 / mg 10g TargetMol Chemicals Inc.
Izilendustat hydrochloride 1-Piperazinecarboxylic acid, 4-[[1-[(4-chlorophenyl)methyl]-1,2-dihydro-3-hydroxy-2-oxo-4-pyridinyl]methyl]-, 1,1-dimethylethyl ester, hydrochloride (1:1) 1303513-80-5