Izilendustat hydrochloride
- CAS No.
- 1303513-80-5
- Chemical Name:
- Izilendustat hydrochloride
- Synonyms
- Izilendustat hydrochloride;1-Piperazinecarboxylic acid, 4-[[1-[(4-chlorophenyl)methyl]-1,2-dihydro-3-hydroxy-2-oxo-4-pyridinyl]methyl]-, 1,1-dimethylethyl ester, hydrochloride (1:1)
- CBNumber:
- CB811014715
- Molecular Formula:
- Molecular Weight:
- 470.39
- MDL Number:
- MOL File:
- 1303513-80-5.mol
FDA UNII | WBQ36T8XFJ |
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Izilendustat hydrochloride Chemical Properties,Uses,Production
Uses
Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)[1][2][3].
References
[1] Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1.
[2] Robert Shalwitz, et al. Methods for increasing the stabilization of hypoxia inducible factor-1 alpha. Patent WO2011057112A1.
[3] Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1.
Izilendustat hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Izilendustat hydrochloride Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19939 | 58 |
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 1000 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 26070 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 58 |
TargetMol Chemicals Inc. | 58 |
View Lastest Price from Izilendustat hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-05-01 | Izilendustat hydrochloride
1303513-80-5
|
US $2140.00-2785.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Izilendustat hydrochloride
1303513-80-5
- US $2140.00-2785.00 / mg
- TargetMol Chemicals Inc.