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1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL structure

CAS No.: 368-63-8

Chemical Name:: 1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL

Synonyms: 3,5-Bis(trifluoromethyl)phenylethanol;1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL;1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL;(1R)-1-[3,7-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL;ALFA-METHYL-3,5-DITRIFLUOROMETHYLBENZYL ALCOHOL;3,5-BIS(TRIFLUOROMETHYL)-A-METHYLBENZYL ALCOHOL;ALPHA-METHYL-3,5-DITRIFLUOROMETHYLBENZYL ALCOHOL;à-Methyl-3,5-bis-(trifluoromethyl)-benzyl alcohol;alpha-methyl-3,5-bis(trifluoromethyl)benzyl alchol;alpha-Methyl-3,5-bis(trifluoromethyl)benzyl alcohol

CBNumber:: CB8113483

Molecular Formula:: C10H8F6O

Molecular Weight:: 258.16

MDL Number:: MFCD01632521

MOL File:: 368-63-8.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:46

Product description	Number	Pack Size	Price
1-(3,5-Bis(trifluoromethyl)phenyl)ethanol	T790983	50mg	$45
1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 99.0%	2802-3-08	1g	$50
alpha-Methyl-3,5-bis(trifluoromethyl)benzylalcohol 99+%	PC7869	1g	$29
1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 99.0%	2802-3-08	5G	$150
1-(3,5-Bis(trifluoromethyl)phenyl)ethanol	Z4663	5g	$223
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1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL Properties

Melting point	70-74℃
Boiling point	175.8±35.0 °C(Predicted)
Density	1.376±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	13.99±0.20(Predicted)
Appearance	White to off-white Solid
CAS DataBase Reference	368-63-8(CAS DataBase Reference)
FDA UNII	03H8X9K3I3

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Hazard Note

Irritant

HS Code

2906290090

NFPA 704

	1
2		0

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	T790983	1-(3,5-Bis(trifluoromethyl)phenyl)ethanol	368-63-8	50mg	$45	2021-12-16	Buy
SynQuest Laboratories	2802-3-08	1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 99.0%	368-63-8	1g	$50	2021-12-16	Buy
Apolloscientific	PC7869	alpha-Methyl-3,5-bis(trifluoromethyl)benzylalcohol 99+%	368-63-8	1g	$29	2021-12-16	Buy
SynQuest Laboratories	2802-3-08	1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 99.0%	368-63-8	5G	$150	2021-12-16	Buy
AK Scientific	Z4663	1-(3,5-Bis(trifluoromethyl)phenyl)ethanol	368-63-8	5g	$223	2021-12-16	Buy

Product number	Packaging	Price	Buy
T790983	50mg	$45	Buy
2802-3-08	1g	$50	Buy
PC7869	1g	$29	Buy
2802-3-08	5G	$150	Buy
Z4663	5g	$223	Buy

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL Chemical Properties,Uses,Production

Synthesis

30071-93-3

7480-35-5

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL

368-63-8

The general procedure for the synthesis of (R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanol from 3,5-bis(trifluoromethyl)acetophenone and cis-1-amino-2,3-dihydro-1H-inden-2-ol is as follows: Example 5: To 2-propanol (21 L), [RuCl2 (p-cymene)]2 (18.4 g), (1S,2R)-cis-1-amino-2,3-dihydro-1H-inden-2-ol (9.0 g), and 1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-one (3 kg) were added, stirred for 30 minutes and thoroughly degassed under vacuum. Subsequently, 5M sodium hydroxide solution (28mL) was added and the mixture was aged for 4-6 hours to ensure complete conversion of the feedstock. Upon completion of the reaction, the reaction mixture was poured into 1N HCl (21 L) and extracted with heptane (2 x 10.5 L). The organic layers were combined, washed with brine, and 1,4-diazabicyclo[2.2.2]octane (740 g) was added. The solution was concentrated to nearly 4 mL/g of alcohol (KF < 200 μg/mL; 2-propanol < 5 vol%). After inoculation at 40°C, the mixture was allowed to cool to room temperature to form crystalline species, which were further cooled to 0°C. The crystalline product was obtained by filtration, washed with cold heptane and dried to give the final DABCO complex in 75-80% yield and ee value >99%.

References

[1] Patent: US2002/22725, 2002, A1
[2] Patent: US2002/52493, 2002, A1
[3] Patent: US2002/52494, 2002, A1
[4] Patent: US6432952, 2002, B1
[5] Patent: US2003/215456, 2003, A1

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL Preparation Products And Raw materials

Raw materials

3',5'-Bis(trifluoromethyl)acetophenone (R)-O-ACETYL-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL (R)-[3,5-bis(trifluoromethyl)phenyl]ethanol 1-AMINO-2-HYDROXYINDANE Isopropyl alcohol

Sodium hydroxide

1of2

Preparation Products

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL Suppliers

Global( 105)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9210	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Changzhou Anxuan Chemical Co., Ltd	+86-0519-89882563 +86-18961279162	andy@anxuanchem.com	China	4327	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49944	58
Sichuan Biosynce Pharmatech Co., Ltd.	+8619950309693	diane@biosynce.com	China	4871	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Baoji Guokang Healthchem Co., Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Changzhou Anxuan Chemical Co., Ltd	58
Aromsyn Co., Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
Sichuan Biosynce Pharmatech Co., Ltd.	58

View Lastest Price from 1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-02-19	1-(3,5-bis(trifluoromethyl)phenyl)ethanol 368-63-8	US $0.00 / KG	1KG	99.1%	100 tons	Honest Joy Holdings Limited
2021-07-13	1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL 368-63-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2020-02-17	1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL 368-63-8	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

1-(3,5-bis(trifluoromethyl)phenyl)ethanol
368-63-8
US $0.00 / KG
99.1%
Honest Joy Holdings Limited

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL
368-63-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL
368-63-8
US $7.00 / KG
99%
Career Henan Chemical Co

368-63-8(1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL)Related Search:

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1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL 1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL 3,5-BIS(TRIFLUOROMETHYL)-A-METHYLBENZYL ALCOHOL ALFA-METHYL-3,5-DITRIFLUOROMETHYLBENZYL ALCOHOL alpha-Methyl-3,5-bis(trifluoromethyl)benzyl alcohol 3,5-Bis(trifluoromethyl)phenylethanol alpha-Methyl-3,5-Bis(trifluoromethyl)Benzylalcohol99+% à-Methyl-3,5-bis-(trifluoromethyl)-benzyl alcohol (1R)-1-[3,7-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL ALPHA-METHYL-3,5-DITRIFLUOROMETHYLBENZYL ALCOHOL 3-AMINO-1,3,4,5-TETRAHYDRO-2H-1-BENZAZEPIN-2-ONE (3-AMINO LACTAM) BenzeneMethanol, a-Methyl-3,5-bis(trifluoroMethyl)- alpha-methyl-3,5-bis(trifluoromethyl)benzyl alchol Benzenemethanol, α-methyl-3,5-bis(trifluoromethyl)- 1-(3,5-Bis(trifluoromethyl)phenyl)ethanol - [B92884] 368-63-8 C10H8F8O PHARMACEUTICAL INTERMEDIATES Aromatic alcohols and diols