ChemicalBook >> CAS DataBase List >>2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE

CAS No.
61856-99-3
Chemical Name:
2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE
Synonyms
EMPO;2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE;2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-2-methyl-, ethyl ester, 1-oxide
CBNumber:
CB8131546
Molecular Formula:
C8H13NO3
Molecular Weight:
171.19
MDL Number:
MFCD04038184
MOL File:
Mol file
Last updated:2025-04-18 09:52:48

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Properties

Boiling point 120 °C(Press: 0.3 Torr)
Density 1.249 g/cm3
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml
pka 1.79±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20618 EMPO ≥98% 61856-99-3 5mg $44 2024-03-01 Buy
Cayman Chemical 20618 EMPO ≥98% 61856-99-3 10mg $84 2024-03-01 Buy
Cayman Chemical 20618 EMPO ≥98% 61856-99-3 25mg $172 2024-03-01 Buy
Cayman Chemical 20618 EMPO ≥98% 61856-99-3 50mg $299 2024-03-01 Buy
AK Scientific 3241CT 2H-Pyrrole-2-carboxylicacid,3,4-dihydro-2-methyl-,ethylester,1-oxide 61856-99-3 25mg $289 2021-12-16 Buy
Product number Packaging Price Buy
20618 5mg $44 Buy
20618 10mg $84 Buy
20618 25mg $172 Buy
20618 50mg $299 Buy
3241CT 25mg $289 Buy

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Chemical Properties,Uses,Production

Description

EMPO is a hydrophilic cyclic nitrone analog of the free radical spin trap DMPO . The EMPO-superoxide adduct (EMPO-OOH) exhibits an ESR spectrum that is similar to the DMPO-OOH spectrum. However, the EMPO-OOH adduct is about 5-8 times more stable (t1/2 = 4.8 – 8.6 min) and does not spontaneously decay to the hydroxyl adduct, making spectral interpretation less difficult.

Uses

EMPO is a free radical scavenger. EMPO is stable in phosphate buffers at physiological pH, its superoxide spin adducts are more durable and no hydroxyl adducts are produced when decaying. EMPO can be used in the study of free radicals[1].

References

[1] Olive G, et al. 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide: evaluation of the spin trapping properties. Free Radic Biol Med. 2000 Feb 1;28(3):403-8. DOI:10.1016/s0891-5849(99)00254-3

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39996 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Yantai Shengkailun Chemical Technology Co., Ltd. 13356901049 mark@sklnchem.cn China 9146 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 400-6206333 13167063860 anhua.mao@aladdin-e.com China 48458 58
Hubei Danding Pharmaceutical Technology Co., Ltd 17701422016 17701422016 3587493084@qq.com China 8941 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58
2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE EMPO 2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-2-methyl-, ethyl ester, 1-oxide 61856-99-3