lactosyl lysosphingolipid
- CAS No.
- 109785-20-8
- Chemical Name:
- lactosyl lysosphingolipid
- Synonyms
- Lactosyl-C18-sphingosine;lactosyl lysosphingolipid;lactosyl-beta-sphingosine;Lactosylsphingosine (d18:1);Lactosyl(β) Sphingosine (d18:1);Lactosyl(ss) Sphingosine (d18:1);Lyso-Lactosylceramide (synthetic);Lactosyl(beta) Sphingosine (d18:1);D-lactosyl-1-1'-D-erythro-sphingosine;D-lactosyl-?1-1'-D-erythro-sphingosine
- CBNumber:
- CB81329335
- Molecular Formula:
- C30H57NO12
- Molecular Weight:
- 623.77308
- MDL Number:
- MFCD07374300
- MOL File:
- 109785-20-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Lactosylsphingosine ≥98.0% (TLC) | 42137 | 1mg | $118 |
| Lactosylsphingosine ≥98.0% (TLC) | 42137 | 5mg | $468 |
| Lactosylsphingosine (d18:1) ≥98% | 24868 | 1mg | $341 |
| Lactosylsphingosine (d18:1) (synthetic) ≥98% | 24867 | 1mg | $121 |
| Lactosyl-C18-sphingosine | L165310 | 2.5mg | $205 |
| Boiling point | 845.8±65.0 °C(Predicted) |
|---|---|
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform:Methanol:Water (2:1:0.1): soluble; DMSO: soluble; Water: soluble |
| form | A solid |
| pka | 11.74±0.45(Predicted) |
| BRN | 5680460 |
| UNSPSC Code | 12352211 |
| NACRES | NA.85 |
lactosyl lysosphingolipid price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 42137 | Lactosylsphingosine ≥98.0% (TLC) | 109785-20-8 | 1mg | $118 | 2023-06-20 | Buy |
| Sigma-Aldrich | 42137 | Lactosylsphingosine ≥98.0% (TLC) | 109785-20-8 | 5mg | $468 | 2023-06-20 | Buy |
| Cayman Chemical | 24868 | Lactosylsphingosine (d18:1) ≥98% | 109785-20-8 | 1mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 24867 | Lactosylsphingosine (d18:1) (synthetic) ≥98% | 109785-20-8 | 1mg | $121 | 2024-03-01 | Buy |
| TRC | L165310 | Lactosyl-C18-sphingosine | 109785-20-8 | 2.5mg | $205 | 2021-12-16 | Buy |
lactosyl lysosphingolipid Chemical Properties,Uses,Production
Description
Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3. [Matreya, LLC. Catalog No. 2088]
Uses
Lactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine?using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial?tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column.
General Description
Lactosyl sphingosine?is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract.
Biochem/physiol Actions
Lactosyl sphingosine?exhibits better hemolytic activity than lysolecithin.
References
[1] S FIORE. Evaluation of synthetic sphingosine, lysosphingolipids and glycosphingolipids as inhibitors of functional responses of human neutrophils.[J]. Biochemical Journal, 1990, 266 1: 25-31. DOI: 10.1042/bj2660025
[2] SUMITA MISHRA Subroto C. Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes.[J]. Glycobiology, 2014, 24 6: 518-531. DOI: 10.1093/glycob/cwu020
[3] VIREAK THON. PmST2: a novel Pasteurella multocida glycolipid α2-3-sialyltransferase.[J]. Glycobiology, 2011, 21 9: 1206-1216. DOI: 10.1093/glycob/cwr054
lactosyl lysosphingolipid Preparation Products And Raw materials
Raw materials
Preparation Products
lactosyl lysosphingolipid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Chengdu Feibo Pharm Technology Co., Ltd | +86 028-84641798 15982321820 | abby@arkpharm.com | China | 10000 | 58 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 6687 | 55 |
| Chengdu Huachun Technology Co., Ltd | 400-1166-196 15982826727 | cdhxsj@163.com | China | 14603 | 60 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 58 |
| Creative Enzymes | 58 |
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| Chengdu Feibo Pharm Technology Co., Ltd | 58 |
| Yichang Zhongyitai Trading Co., Ltd. | 58 |
| Sigma-Aldrich | 80 |
| Alfa Chemistry | 60 |
| Codow Chemical Co.,Ltd. | 55 |
| Chengdu Huachun Technology Co., Ltd | 60 |
View Lastest Price from lactosyl lysosphingolipid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-29 | Lactosylsphingosine (d18:1)
109785-20-8
|
US $1199.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Lactosylsphingosine (d18:1)
109785-20-8
- US $1199.00 / mg
- TargetMol Chemicals Inc.
