Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Hydroxypyridine

2-Hydroxypyridine

2-Hydroxypyridine Structure
2-Hydroxypyridine structure
CAS No.
142-08-5
Chemical Name:
2-Hydroxypyridine
Synonyms
Pyridin-2(1H)-one;2-PYRIDONE;2(1h)-pyridinone;2-Pyridinol;Pyridin-2-one;2(1H)-PYRIDONE;2-PYRIDON;2-PYRIDOL;Pyridone-2;A-PYRIDONE
CBNumber:
CB8137755
Molecular Formula:
C5H5NO
Molecular Weight:
95.1
MDL Number:
MFCD00006268
MOL File:
142-08-5.mol
MSDS File:
SDS
Last updated:2026-04-13 16:10:10
Product description Number Pack Size Price
2-Hydroxypyridine 97% H56800 25g $59.2
Levetiracetam impurity C European Pharmacopoeia (EP) Reference Standard Y0001256 15 mg $167
2-Hydroxypyridine analytical standard 41152 100mg $67.2
2-Hydroxypyridine >98.0%(GC)(T) H0330 25g $56
2-Hydroxypyridine >98.0%(GC)(T) H0330 250g $401
More product size
Request For Quotation

2-Hydroxypyridine Properties

Melting point 105-107 °C (lit.)
Boiling point 280-281 °C (lit.)
Density 1.39
FLAVIS Number 14.118 | 2-Hydroxypyridine
refractive index 1.5939 (estimate)
Flash point 210 °C
storage temp. Sealed in dry,Room Temperature
solubility 450g/l
pka 0.75(at 20℃)
form Liquid
color Colorless to yellow to brown, darken on storage with no loss of purity
Water Solubility Soluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether.
BRN 105786
InChI 1S/C5H5NO/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)
InChIKey UBQKCCHYAOITMY-UHFFFAOYSA-N
SMILES Oc1ccccn1
LogP -0.593 (est)
CAS DataBase Reference 142-08-5(CAS DataBase Reference)
FDA UNII 6770O3A2I5
NIST Chemistry Reference 2(1H)-Pyridinone(142-08-5)
EPA Substance Registry System 2(1H)-Pyridinone (142-08-5)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P330+P331+P310
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  Xi,Xn,T
Risk Statements  36/37/38-40-25
Safety Statements  26-36-37/39-22-45-36/37/39
RIDADR  UN2811
WGK Germany  3
RTECS  UV1144050
F  8
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  29333990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Toxicity LD50 ipr-mus: 410 mg/kg TOXIA6 23,815,85
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
2 0

2-Hydroxypyridine price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H56800 2-Hydroxypyridine 97% 142-08-5 25g $59.2 2026-03-19 Buy
Sigma-Aldrich Y0001256 Levetiracetam impurity C European Pharmacopoeia (EP) Reference Standard 142-08-5 15 mg $167 2026-03-19 Buy
Sigma-Aldrich 41152 2-Hydroxypyridine analytical standard 142-08-5 100mg $67.2 2022-05-15 Buy
TCI Chemical H0330 2-Hydroxypyridine >98.0%(GC)(T) 142-08-5 25g $56 2026-03-19 Buy
TCI Chemical H0330 2-Hydroxypyridine >98.0%(GC)(T) 142-08-5 250g $401 2026-03-19 Buy
Product number Packaging Price Buy
H56800 25g $59.2 Buy
Y0001256 15 mg $167 Buy
41152 100mg $67.2 Buy
H0330 25g $56 Buy
H0330 250g $401 Buy

2-Hydroxypyridine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal

Uses

Catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.

Uses

2-Hydroxypyridine is a bifunctional catalyst for a wide variety of acylation reactions, catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate. It is used in peptide synthesis.

Definition

ChEBI: 2-Hydroxypyridine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2. It has a role as a plant metabolite.

General Description

2-Hydroxypyridine, an enolic tautomer of 2-pyridone, belongs to the class of volatile organic compounds (VOCs).

Safety Profile

Moderately toxic by intraperitoneal and intravenous routes. A combustible liquid. When heated to decomposition it emits toxic vapors of NOx.

Purification Methods

Distil the pyridone under vacuum to remove coloured impurity, then recrystallise from *benzene, CCl4, EtOH or CHCl3/diethyl ether. It can be sublimed under high vacuum. [DePue et al. J Am Chem Soc 107 2131 1985, Beilstein 21/7 V 106.]

2-Hydroxypyridine synthesis

110-89-4
111-26-2
105-56-6
372-31-6
142-08-5
Synthesis of 2-Hydroxypyridine from Piperidine and Hexylamine and Ethyl cyanoacetate and Ethyl 4,4,4-trifluoroacetoacetate

2-Hydroxypyridine Preparation Products And Raw materials

Raw materials

1,3-Dicyclohexylthiourea Allyl isothiocyanate Dicyclohexylcarbodiimide Carbonic acid, 1,1-dimethylethyl 2-pyridinyl ester (9CI) 2(1H)-Pyridinone, 1-[[(4-methoxy-1-naphthalenyl)carbonyl]oxy]- (9CI)
BOC-L-Tyrosine

1of2

Preparation Products

DI-2-PYRIDYL THIONOCARBONATE Reactive Brilliant Yellow M-7G 2-Hydroxy-5-bromopyridine 5-CHLOROPYRIDIN-2(1H)-ONE disodium 4-[[5-(aminocarbonyl)-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl]azo]-6-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzene-1,3-disulphonate
3,5-DICHLORO-2-PYRIDONE 2,3-Dihydroxypyridine (2-OXOPYRIDIN-1(2H)-YL)ACETIC ACID 2-HYDRAZINO-3-NITROPYRIDINE

1of2

2-Hydroxypyridine Suppliers

Global( 617)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Wisdom Chemicals Co., Ltd.
+8613701363759 market@wisdomchem.com China 254 58
JINING XINHE CHEMICAL CO., LTD 		+8615318402391 sales@xinhepharma.com China 809 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16513 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +8618949832763 info@tnjchem.com China 2988 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29824 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Supplier Advantage
Beijing Wisdom Chemicals Co., Ltd.
58
JINING XINHE CHEMICAL CO., LTD 		58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hefei TNJ Chemical Industry Co.,Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58
career henan chemical co 		58
Standardpharm Co. Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58

Related articles

View Lastest Price from 2-Hydroxypyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
α-Pyridone pictures 2026-04-13 α-Pyridone
142-08-5
 US $29.00 / g 99.96% 10g TargetMol Chemicals Inc.
2-Hydroxypyridine pictures 2026-04-13 2-Hydroxypyridine
142-08-5
 US $0.00-0.00 / kg 1kg 98%min 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
2-Hydroxypyridine pictures 2025-12-01 2-Hydroxypyridine
142-08-5
 US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
  • α-Pyridone pictures
  • α-Pyridone
    142-08-5
  • US $29.00 / g
  • 99.96%
  • TargetMol Chemicals Inc.

2-Hydroxypyridine Spectrum

2-Hydroxypyridine(142-08-5)MS2-Hydroxypyridine(142-08-5)1HNMR2-Hydroxypyridine(142-08-5)13CNMR2-Hydroxypyridine(142-08-5)IR12-Hydroxypyridine(142-08-5)IR22-Hydroxypyridine(142-08-5)Raman

142-08-5(2-Hydroxypyridine)Related Search:

Hydroxy silicone oil 4-Methylpyridine (+/-)-NICOTINE 2,3,4-Trihydroxybenzoic acid 2-(Hydroxymethyl)pyridine
2-Chloro-5-chloromethylpyridine Sulfasalazine 2,5-Dimethylpyridine Chromium picolinate 4-Hydroxypyridine
Pyridin-2-ol Levetiracetam impurity 8 Levetiracetam acid LevetiracetaM IMpurity B (S)-N-(1-aMino-1-oxobutan-2-yl)-4-chlorobutanaMide
alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid Levetiracetam impurity 6 Levetiracetam

1of4

1-Hydroxy-2-pyridine alpha-Pyridone Pyridone-2 AURORA KA-3075 A-PYRIDONE TIMTEC-BB SBB004392 a-Hydroxypyridine 1,2-dihydro-2-oxopyridine 2(1H)-PYRIDONE 1H-2-Pyridone 1h-pyridin-2-one 2-pyridinone 2-PYRIDON 2-PYRIDOL 2-oxopyridine 2-Pyridinol (2-hydroxy-pyridin) 2-hydroxypyridine (intermediate of benzoxazole) Diydrozylpyridine 2-Hydroxypyridine(2-Pyridinol) 2-Hydroxypyridine 2-Pyridinol 2-Hydroxypyridine, 98+% 2-HYDROXYPYRIDINE pure 2-Pyridinol 2-Pyridone 2-PYRIDINOL FOR SYNTHESIS 2-hydroxypyridate 2(1H)-Pyridone, 2-Pyridinol 2-Hydroxypyridine,97% Pyridin-2-one 2-Hydroxypyridine 97% 3-Fluoro-4-Methylbenzenethiol, >95% Levetiracetam-3 Levetiracetam Impurity 3（Levetiracetam EP Impurity C） Levetiracetam EP Impurity C 2-Hydroxypyridine> 2-Hydroxypyridine, 98%, for synthesis Levetiracetam impurity C CRS 2-Hydroxypyridine ISO 9001：2015 REACH α-Pyridone α-Pyridone (Levetiracetam Impurity) Levetiracetam impurities520 Levetiracetam impurities12 2-HYDROXYPYRIDINE (2(1H)-Pyridinol) >98% α-Pyridone, 10 mM in DMSO 2-pyridone A-PYRIDONE Pyridinone 2(1h)-pyridinone 2-PYRIDONE Pyridin-2(1H)-one 142-08-5 2762-00-6 148-08-5 421-08-5 C5H4NOH C5H5NO Building Blocks C5 Pyridines