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CHRYSOSPLENOLD

CHRYSOSPLENOLD Structure
CHRYSOSPLENOLD structure
CAS No.
14965-20-9
Chemical Name:
CHRYSOSPLENOLD
Synonyms
Chrysosplel D;CHRYSOSPLENOLD;7-Methylaxillarin;Chrysosplenol D, 10 mM in DMSO;Quercetagetin 3,6,7-triMethyl ether;5,3',4'-Trihydroxy-3,6,7-trimethoxyflavone;3,6,7-Trimethoxy-3',4',5-trihydroxyflavone;2-(3,4-dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxychromen-4-one;2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-chromen-4-one;2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one
CBNumber:
CB81404010
Molecular Formula:
C18H16O8
Molecular Weight:
360.31
MDL Number:
MFCD01548059
MOL File:
14965-20-9.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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CHRYSOSPLENOLD Properties

Melting point 236-238 °C
Boiling point 645.0±55.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
storage temp. 4°C, away from moisture and light
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder
pka 6.13±0.40(Predicted)
color Yellow
InChI InChI=1S/C18H16O8/c1-23-12-7-11-13(14(21)17(12)24-2)15(22)18(25-3)16(26-11)8-4-5-9(19)10(20)6-8/h4-7,19-21H,1-3H3
InChIKey BYWLLSQTJBXAPV-UHFFFAOYSA-N
SMILES C1(C2=CC=C(O)C(O)=C2)OC2=CC(OC)=C(OC)C(O)=C2C(=O)C=1OC
FDA UNII GV8SR5RV6Z

CHRYSOSPLENOLD price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 361738 3,6,7-Trimethylquercetagetin ~98%(HPLC) 14965-20-9 5mg $1104 2026-06-03 Buy
Biosynth PAA96520 Chrysosplenol D 14965-20-9 1mg $392.65 2026-06-04 Buy
Biosynth PAA96520 Chrysosplenol D 14965-20-9 2mg $628.24 2026-06-04 Buy
Biosynth PAA96520 Chrysosplenol D 14965-20-9 5mg $1256.45 2026-06-04 Buy
Biosynth PAA96520 Chrysosplenol D 14965-20-9 10mg $1884.7 2026-06-04 Buy
Product number Packaging Price Buy
361738 5mg $1104 Buy
PAA96520 1mg $392.65 Buy
PAA96520 2mg $628.24 Buy
PAA96520 5mg $1256.45 Buy
PAA96520 10mg $1884.7 Buy

CHRYSOSPLENOLD Chemical Properties, Uses, Production

Uses

Chrysosplenol D is a methoxy flavonoid that induces ERK1/2-mediated apoptosis in triple negative human breast cancer cells. Chrysosplenol D also exhibits anti-inflammatory and moderate antitrypanosomal activities[1][2][3][4].

Definition

ChEBI: 3',4',5-trihydroxy-3,6,7-trimethoxyflavone is a trimethoxyflavone that is the 3,6,7-trimethyl ether derivative of quercetagetin. It has a role as an antineoplastic agent and a metabolite. It is a trihydroxyflavone and a trimethoxyflavone. It is functionally related to a quercetagetin.

in vivo

Chrysosplenol D (30 μM; 3 d) inhibits MDA-MB-231 tumor growth on chick chorioallantoic membranes[2].
Chrysosplenol D (0.07-0.28 mmol/kg) protects against LPS-induced systemic inflammatory response syndrome (SIRS) in mice[4].
Chrysosplenol D (1-1.5 μmol/cm2) inhibits croton oil-induced ear edema in mice[4].

References

[1] Habib ES, et, al. Anti-inflammatory effect of methoxyflavonoids from Chiliadenus montanus (Jasonia Montana) growing in Egypt. Nat Prod Res. 2020 Aug 4;1-5. DOI:10.1080/14786419.2020.1802272
[2] Lang SJ, et, al. Chrysosplenol d, a Flavonol from Artemisia annua, Induces ERK1/2-Mediated Apoptosis in Triple Negative Human Breast Cancer Cells. Int J Mol Sci. 2020 Jun 8;21(11):4090. DOI:10.3390/ijms21114090
[3] Skaf J, et, al. Improving anti-trypanosomal activity of alkamides isolated from Achillea fragrantissima. Fitoterapia. 2018 Mar;125:191-198. DOI:10.1016/j.fitote.2017.11.001
[4] Li YJ, et, al. Flavonoids casticin and chrysosplenol D from Artemisia annua L. inhibit inflammation in vitro and in vivo. Toxicol Appl Pharmacol. 2015 Aug 1;286(3):151-8. DOI:10.1016/j.taap.2015.04.005

CHRYSOSPLENOLD Preparation Products And Raw materials

Raw materials

Preparation Products

CHRYSOSPLENOLD Suppliers

Global Suppliers ( 83)
Supplier Tel Email Country ProdList Advantage
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Winherb Medical Technology Co., Ltd. 17301719108 13341702378 winherb@126.com China 1245 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8135 55
ALB Technology Limited 702-983-3769 sales@albtechnology.com United States 2992 55
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Supplier Advantage
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Chembest Research Laboratories Limited 61
BioBioPha Co., Ltd. 65
Chengdu Biopurify Phytochemicals Ltd. 60
Shanghai Winherb Medical Technology Co., Ltd. 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Shanghai Yongye Biotechnology Co., Ltd. 55
ALB Technology Limited 55
Wuhan ChemFaces Biochemical Co., Ltd. 55
EMMX Biotechnology LLC 60

View Latest Price from CHRYSOSPLENOLD manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Chrysosplenol D pictures 2026-07-27 Chrysosplenol D
14965-20-9
 $81.00-322.00 99.98% 10g TargetMol Chemicals Inc.

CHRYSOSPLENOLD Spectrum

CHRYSOSPLENOLD(14965-20-9)1HNMR

14965-20-9 (CHRYSOSPLENOLD) Related Search:

4',5-Dihydroxy-7-methoxyflavone PONCIRIN Naringenin 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers)
hydroxygenkwanin Quercetin-7-O-β-D-glucopyranoside MEDICAGOL MOSLOFLAVONE GARDENIN B

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CHRYSOSPLENOLD 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one 3,6,7-Trimethoxy-3',4',5-trihydroxyflavone Chrysosplel D 5,3',4'-Trihydroxy-3,6,7-trimethoxyflavone 7-Methylaxillarin Quercetagetin 3,6,7-triMethyl ether 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxychromen-4-one 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxy- cancer,Apoptosis,inhibit,ERK1/2,Inhibitor,antitrypanosomal,breast,Chrysosplenol D,anti-inflammatory 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-chromen-4-one Chrysosplenol D, 10 mM in DMSO 14965-20-9