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ChemicalBook >> CAS DataBase List >>2',4,4',6'-TETRAHYDROXYCHALCONE

2',4,4',6'-TETRAHYDROXYCHALCONE

2',4,4',6'-TETRAHYDROXYCHALCONE Structure
2',4,4',6'-TETRAHYDROXYCHALCONE structure
CAS No.
25515-46-2
Chemical Name:
2',4,4',6'-TETRAHYDROXYCHALCONE
Synonyms
Naringenin chalcon;cNaringenin chalcone;Naringenin chalcone-RM;Naringenin chalcone (Standard);2',4,4',6'-TETRAHYDROXYCHALCONE;1-(2,4,6-Trihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one;(E)-3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one;2-Propen-1-one, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, (2E)-
CBNumber:
CB81407576
Molecular Formula:
C15H12O5
Molecular Weight:
272.25
MDL Number:
MFCD00016762
MOL File:
25515-46-2.mol
MSDS File:
SDS
Last updated:2026-05-22 14:23:19
Product description Number Pack Size Price
Naringenin chalcon phyproof Reference Substance PHL83877 10mg $622
Naringenin chalcone FN76317 2mg $199.56
Naringenin chalcone FN76317 5mg $408.2
Naringenin chalcone FN76317 10mg $725.6
Naringenin chalcone FN76317 20mg $1270
Request For Quotation

2',4,4',6'-TETRAHYDROXYCHALCONE Properties

Boiling point 538.7±50.0 °C(Predicted)
Density 1.483±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 6.94±0.40(Predicted)
Major Application food and beverages
InChI 1S/C15H12O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-8,16-17,19-20H/b6-3+
InChIKey YQHMWTPYORBCMF-ZZXKWVIFSA-N
SMILES Oc1c(c(cc(c1)O)O)C(=O)\C=C\c2ccc(cc2)O
FDA UNII YCF6Z24AS2
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

2',4,4',6'-TETRAHYDROXYCHALCONE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL83877 Naringenin chalcon phyproof Reference Substance 25515-46-2 10mg $622 2026-04-30 Buy
Biosynth FN76317 Naringenin chalcone 25515-46-2 2mg $199.56 2026-06-04 Buy
Biosynth FN76317 Naringenin chalcone 25515-46-2 5mg $408.2 2026-06-04 Buy
Biosynth FN76317 Naringenin chalcone 25515-46-2 10mg $725.6 2026-06-04 Buy
Biosynth FN76317 Naringenin chalcone 25515-46-2 20mg $1270 2026-06-04 Buy
Product number Packaging Price Buy
PHL83877 10mg $622 Buy
FN76317 2mg $199.56 Buy
FN76317 5mg $408.2 Buy
FN76317 10mg $725.6 Buy
FN76317 20mg $1270 Buy

2',4,4',6'-TETRAHYDROXYCHALCONE Chemical Properties,Uses,Production

Uses

food and beverages

Definition

ChEBI: 2',4,4',6'-tetrahydroxychalcone is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' ,4, 4', and 6' respectively. It has a role as a metabolite, an anti-allergic agent and an anti-inflammatory agent. It is a polyphenol and a member of chalcones. It is functionally related to a trans-chalcone.

in vivo

(E)-Naringenin chalcone (0.8 mg/kg, oral administration) shows anti-allergic effect in type I allergic mice[1].
(E)-Naringenin chalcone (0.8 mg/kg, oral administration) suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells in allergic airway inflammatory mice[3].

Animal Model:Mouse type I allergic model[1]
Dosage:0.8 mg/kg
Administration:Oral administration
Result:Inhibited the ear-swelling response, with the inhibitory ratio of 46.7%.
Animal Model:Allergic airway inflammation induced in mice[3]
Dosage:0.8 mg/kg
Administration:Oral administration, daily
Result:Decreased cell numbers of the infiltrating leukocyte and eosinophils.
Decreased Muc5ac and gob-5 expression in the lungs.

2',4,4',6'-TETRAHYDROXYCHALCONE Preparation Products And Raw materials

Raw materials

Preparation Products

2',4,4',6'-TETRAHYDROXYCHALCONE Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Winherb Medical Technology Co., Ltd. 17301719108 13341702378 winherb@126.com China 1245 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518 shyysw007@163.com China 89667 60
Henan Alfachem Co.,Ltd. 0371-55051623 18137891487 3983243027@qq.com China 9957 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27602 58
Guangzhou Yunmen Biotechnology Co., Ltd 0751-18902340975/189023400307 18902340307 3356812514@qq.com China 9225 58
Guangdong wengjiang Chemical Reagent Co., Ltd. 0751-2815987 13927875076 3007432263@qq.com China 10000 58
Shanghai Taopu Industrial Co., LTD 15900573766 18018507602 3165608826@qq.com China 4398 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Winherb Medical Technology Co., Ltd. 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Henan Alfachem Co.,Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Guangzhou Yunmen Biotechnology Co., Ltd 58
Guangdong wengjiang Chemical Reagent Co., Ltd. 58
Shanghai Taopu Industrial Co., LTD 58

View Lastest Price from 2',4,4',6'-TETRAHYDROXYCHALCONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Naringenin chalcone pictures 2026-05-22 Naringenin chalcone
25515-46-2
 $39.00-80.00 99.65% 10g TargetMol Chemicals Inc.

2',4,4',6'-TETRAHYDROXYCHALCONE Spectrum

2',4,4',6'-TETRAHYDROXYCHALCONE(25515-46-2)1HNMR

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2',4,4',6'-TETRAHYDROXYCHALCONE 1-(2,4,6-Trihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one Naringenin chalcon 2-Propen-1-one, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, (2E)- cNaringenin chalcone (E)-3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one Naringenin chalcone-RM Naringenin chalcone (Standard) 25515-46-2