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ChemicalBook >> CAS DataBase List >>3-iodo-5-(trifluoromethyl)-2-pyridinylamine

3-iodo-5-(trifluoromethyl)-2-pyridinylamine

3-iodo-5-(trifluoromethyl)-2-pyridinylamine Structure
3-iodo-5-(trifluoromethyl)-2-pyridinylamine structure
CAS No.
211308-82-6
Chemical Name:
3-iodo-5-(trifluoromethyl)-2-pyridinylamine
Synonyms
3-IODO-5-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE;3-iodo-5-(trifluoromethyl)pyridine-2-amine;-iodo-5-(trifluoromethyl)-2-pyridinylamine;3-Iodo-5-trifluoroMethyl-pyridin-2-ylaMine;3-iodo-5-(trifluoromethyl)-2-pyridinylamine;2-Pyridinamine, 3-iodo-5-(trifluoromethyl)-;2-Amino-3-iodo-5-(trifluoromethyl)-pyridine;3-Iodo-5-(trifluoromethyl)-2-pyridinylamine(en);1H-Imidazole-4-carboxylicacid,1-(7-bromophenyl)-;3-IODO-5-TRIFLUOROMETHYL-PYRIDIN-2-YLAMINE (NOT RESTRICTED/P - ROHIBITED) (LAB RESEARCH CHEMICAL)
CBNumber:
CB81526574
Molecular Formula:
C6H4F3IN2
Molecular Weight:
288.01
MDL Number:
MFCD10697686
MOL File:
211308-82-6.mol
MSDS File:
SDS
Last updated:2026-05-28 04:52:03
Product description Number Pack Size Price
3-Iodo-5-(trifluoromethyl)pyridin-2-amine Aldrich ADE000574 1g $761
2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% PC200189 100mg $21
2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% PC200189 250mg $24
2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% PC200189 1g $29
2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% PC200189 5g $88
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3-iodo-5-(trifluoromethyl)-2-pyridinylamine Properties

Melting point 97-98°
Boiling point 269.4±40.0 °C(Predicted)
Density 2.049±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 2.15±0.49(Predicted)
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HazardClass  IRRITANT
HS Code  2933399990

3-iodo-5-(trifluoromethyl)-2-pyridinylamine price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ADE000574 3-Iodo-5-(trifluoromethyl)pyridin-2-amine Aldrich 211308-82-6 1g $761 2023-06-20 Buy
Apolloscientific PC200189 2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% 211308-82-6 100mg $21 2026-06-04 Buy
Apolloscientific PC200189 2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% 211308-82-6 250mg $24 2026-06-04 Buy
Apolloscientific PC200189 2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% 211308-82-6 1g $29 2026-06-04 Buy
Apolloscientific PC200189 2-Amino-3-iodo-5-(trifluoromethyl)pyridine 97% 211308-82-6 5g $88 2026-06-04 Buy
Product number Packaging Price Buy
ADE000574 1g $761 Buy
PC200189 100mg $21 Buy
PC200189 250mg $24 Buy
PC200189 1g $29 Buy
PC200189 5g $88 Buy

3-iodo-5-(trifluoromethyl)-2-pyridinylamine Chemical Properties,Uses,Production

Synthesis

5-(Trifluoromethyl)pyridin-2-amine

74784-70-6

3-iodo-5-(trifluoromethyl)-2-pyridinylamine

211308-82-6

Concentrated sulfuric acid (5 mL), periodate (26 g, 123 mmol) and iodine (62 g, 246 mmol) were sequentially added to a stirred solution of 5-(trifluoromethyl)pyridin-2-amine (100 g, 617 mmol) in acetic acid (1 L) under argon protection and at room temperature. The reaction mixture was heated to 80 °C and stirred continuously for 16 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the complete consumption of the raw materials, the reaction mixture was cooled to 0 °C and alkalized with sodium hydroxide solution (200 mL) to precipitate the solid product. The solid was collected by filtration and concentrated under vacuum to afford the target compound 3-iodo-5-(trifluoromethyl)pyridin-2-amine (120 g, 67% yield) as an off-white solid. The product was characterized by 1H NMR (DMSO-d6, 500 MHz): δ 8.27 (s, 1H), 8.16 (s, 1H), 6.87 (brs, 2H); TLC conditions: 10% ethyl acetate/hexane (Rf 0.4).

References

[1] Patent: WO2008/79346, 2008, A1. Location in patent: Page/Page column 58
[2] Patent: WO2017/31325, 2017, A1. Location in patent: Paragraph 0522
[3] Patent: WO2017/133667, 2017, A1. Location in patent: Page/Page column 116; 117
[4] Journal of Medicinal Chemistry, 2013, vol. 56, # 3, p. 1160 - 1170
[5] Patent: US2005/277681, 2005, A1. Location in patent: Page/Page column 26

3-iodo-5-(trifluoromethyl)-2-pyridinylamine Preparation Products And Raw materials

Raw materials

N-(3-Iodo-5-(trifluoromethyl)pyridin-2-yl)-pivalamide 5-(Trifluoromethyl)pyridin-2-amine Acetic acid Sulfuric acid iodine
Periodic acid

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Preparation Products

3-iodo-5-(trifluoromethyl)-2-pyridinylamine Suppliers

Global( 93)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 14014 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471; sales@sarms4muscle.com China 10473 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Changzhou AniKare Pharmatech Co., Ltd. 		+86-0519-8359-8696 +8618018249389 sales@anikare.com China 9981 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Supplier Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Changzhou AniKare Pharmatech Co., Ltd. 		58
Aladdin Scientific 		58

View Lastest Price from 3-iodo-5-(trifluoromethyl)-2-pyridinylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Iodo-5-(trifluoromethyl)pyridin-2-amine pictures 2020-02-01 3-Iodo-5-(trifluoromethyl)pyridin-2-amine
211308-82-6
 $1.00 1KG Min98% HPLC Career Henan Chemical Co

3-iodo-5-(trifluoromethyl)-2-pyridinylamine Spectrum

3-iodo-5-(trifluoromethyl)-2-pyridinylamine(211308-82-6)1HNMR3-iodo-5-(trifluoromethyl)-2-pyridinylamine(211308-82-6)19FNMR

211308-82-6(3-iodo-5-(trifluoromethyl)-2-pyridinylamine)Related Search:

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6-AMino-5-iodo-nicotinic acid Methyl ester methyl 6-amino-5-chloronicotinate 2-AMINO-3-IODO-5-NITROPYRIDINE 3-Chloro-5-(trifluoromethyl)pyridin-2-amine 6-AMINO-5-CHLORO-NICOTINONITRILE
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2-Amino-3-iodo-5-(trifluoromethyl)-pyridine 3-Iodo-5-trifluoroMethyl-pyridin-2-ylaMine -iodo-5-(trifluoromethyl)-2-pyridinylamine 2-Pyridinamine, 3-iodo-5-(trifluoromethyl)- 3-iodo-5-(trifluoromethyl)-2-pyridinylamine 3-Iodo-5-(trifluoromethyl)-2-pyridinylamine(en) 3-IODO-5-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE 3-IODO-5-TRIFLUOROMETHYL-PYRIDIN-2-YLAMINE (NOT RESTRICTED/P - ROHIBITED) (LAB RESEARCH CHEMICAL) 3-iodo-5-(trifluoromethyl)pyridine-2-amine 1H-Imidazole-4-carboxylicacid,1-(7-bromophenyl)- 211308-82-6 amine|alkyl bromide