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Pyridine-3-sulfonyl chloride hydrochloride

CAS No.
42899-76-3
Chemical Name:
Pyridine-3-sulfonyl chloride hydrochloride
Synonyms
Pyridine-3-suL;TIMTEC-BB SBB010621;ASINEX-REAG BAS 13031029;Pyridine-3-sulfonyl chlor...;Pyridine-3-sulfonylchlorideHCl;Pyridine-3-Sulphonyl Chloride Hcl;Pyridine-3-sulfonylchloride HCl Salt;Vonorazan Impurity 66(hydrochloride);Vonoprazan Impurity 66(Hydrochloride);3-(Chlorosulphonyl)pyridine hydrochloride
CBNumber:
CB8153122
Molecular Formula:
C5H5Cl2NO2S
Molecular Weight:
214.07
MDL Number:
MFCD04035552
MOL File:
42899-76-3.mol
MSDS File:
SDS
Last updated:2026-05-28 04:53:14
Product description Number Pack Size Price
Pyridine-3-sulfonyl chloride 95% 749273 1G $52
PYRIDINE-3-SULFONYL CHLORIDE HCL 95% 65424 0.25G $60
Pyridine-3-sulfonyl chloride hydrochloride 019750 1.00g $32
Pyridine-3-sulfonyl chloride hydrochloride 019750 5.00g $103
Pyridine-3-sulfonyl chloride hydrochloride 97.0% P0085 5g $140
More product size

Pyridine-3-sulfonyl chloride hydrochloride Properties

Melting point 120-126
Flash point >110℃
storage temp. Inert atmosphere,Store in freezer, under -20°C
Appearance white solid
Water Solubility Reacts with water.
Sensitive Moisture Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  14-29-34
Safety Statements  8-22-26-30-45-36/37/39
RIDADR  UN 3265 8 / PGII
Hazard Note  Corrosive/Keep Cold under -20C
HazardClass  IRRITANT
HazardClass  8
HS Code  29333990
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 2
W

Pyridine-3-sulfonyl chloride hydrochloride price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 749273 Pyridine-3-sulfonyl chloride 95% 42899-76-3 1G $52 2025-07-31 Buy
AstaTech 65424 PYRIDINE-3-SULFONYL CHLORIDE HCL 95% 42899-76-3 0.25G $60 2026-04-30 Buy
Matrix Scientific 019750 Pyridine-3-sulfonyl chloride hydrochloride 42899-76-3 1.00g $32 2026-05-18 Buy
Matrix Scientific 019750 Pyridine-3-sulfonyl chloride hydrochloride 42899-76-3 5.00g $103 2026-05-18 Buy
Synthonix P0085 Pyridine-3-sulfonyl chloride hydrochloride 97.0% 42899-76-3 5g $140 2026-05-06 Buy
Product number Packaging Price Buy
749273 1G $52 Buy
65424 0.25G $60 Buy
019750 1.00g $32 Buy
019750 5.00g $103 Buy
P0085 5g $140 Buy

Pyridine-3-sulfonyl chloride hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White solid

Synthesis

3-Pyridinesulfonic acid

636-73-7

Pyridine-3-sulfonyl chloride hydrochloride

42899-76-3

General procedure for the synthesis of pyridine-3-sulfonyl chloride hydrochloride from 3-pyridinesulfonic acid: 3-pyridinesulfonic acid (3.00 g, 18.8 mmol) was mixed with phosphorus pentachloride (PCl5, 4.79 g, 23.0 mmol) in phosphorus oxychloride (POCl3, 6 mL). The reaction mixture was stirred and reacted at 120°C overnight (15 h). After completion of the reaction, it was cooled to room temperature, diluted with chloroform (CHCl3, 20 mL) and saturated with hydrogen chloride gas (HCl(g)). The precipitated white precipitate was collected by filtration, washed with chloroform and dried under reduced pressure to give the title compound pyridine-3-sulfonyl chloride hydrochloride (3.36 g, 83% yield) as a white powder.

References

[1] Advanced Synthesis and Catalysis, 2004, vol. 346, # 8, p. 925 - 928
[2] Patent: WO2008/3703, 2008, A1. Location in patent: Page/Page column 82
[3] Patent: US2007/60623, 2007, A1. Location in patent: Page/Page column 24
[4] Patent: WO2006/36024, 2006, A1. Location in patent: Page/Page column 160
[5] Patent: EP2336107, 2015, B1. Location in patent: Paragraph 0306

636-73-7
42899-76-3
Synthesis of Pyridine-3-sulfonyl chloride hydrochloride from 3-Pyridinesulfonic acid
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View Lastest Price from Pyridine-3-sulfonyl chloride hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PYRIDINE-3-SULFONYL CHLORIDE  pictures 2025-11-18 PYRIDINE-3-SULFONYL CHLORIDE
42899-76-3
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
PYRIDINE-3-SULFONYL CHLORIDE pictures 2019-07-06 PYRIDINE-3-SULFONYL CHLORIDE
42899-76-3
US $1.00 / kg 1kg 99% Customized Career Henan Chemical Co
TIMTEC-BB SBB010621 Pyridine-3-sulphonyl chloride hydrochloride, tech Pyridine-3-sulfonylchlorideHCl ASINEX-REAG BAS 13031029 Pyridine-3-sulfonyl chloride hydrochloride ,95% Pyridine-3-sulfonyl chlor... Pyridine-3-Sulphonyl Chloride Hcl 3-(Chlorosulphonyl)pyridine hydrochloride Pyridine-3-sulfonyl chloride hydrochloride, tech 3-Pyridinesulfonylchloride, hydrochloride (1:1) Pyridine-3-suL PYRIDINE-3-SULFONYL CHLORIDE ISO 9001:2015 REACH PYRIDINE-3-SULFONYL CHLORIDE HYDROCHLORIDE Vonoprazan Impurity 66(Hydrochloride) Pyridine-3-sulfonylchloride HCl Salt Vonorazan Impurity 66(hydrochloride) Pyridine-3-sulfonyl chloride HCl, CAS 42899-76-3 42899-76-3 C5H4NO2ClS C5H5Cl2NO2S C5H4ClNO2SClH Heterocycle-Pyridine series blocks Pyridines