2-(2-Aminothiazol-4-yl)glyoxylic acid
- CAS No.
- 73150-67-1
- Chemical Name:
- 2-(2-Aminothiazol-4-yl)glyoxylic acid
- Synonyms
- ATGA;2-(2-AMinothiazol-4-yl)Glyoxy;2-Amino-4-thiazoleglyoxylic Acid;2-amino-α-oxothiazol-4-acetic acid;2-Amino-α-oxo-4-thiazoleacetic acid;4-Thiazoleacetic acid, 2-amino-α-oxo-;2-amino-alpha-oxothiazol-4-acetic acid;2-(2-AMINOTHIAZOL-4-YL) GLYOXYLIC ACID;2-(2-Amino-4-thiazolyl)-2-oxoacetic Acid;2-(2-AMINOTHIAZOL-4-YL)-2-OXO-ACETIC ACID
- CBNumber:
- CB8170233
- Molecular Formula:
- C5H4N2O3S
- Molecular Weight:
- 172.16
- MDL Number:
- MFCD00274532
- MOL File:
- 73150-67-1.mol
- MSDS File:
- SDS
| Boiling point | 395.7±24.0 °C(Predicted) |
|---|---|
| Density | 1.711±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO |
| pka | 1.25±0.54(Predicted) |
| form | Solid |
| color | Pale Yellow |
| InChI | InChI=1S/C5H4N2O3S/c6-5-7-2(1-11-5)3(8)4(9)10/h1H,(H2,6,7)(H,9,10) |
| InChIKey | VMASTYPGLHRVNL-UHFFFAOYSA-N |
| SMILES | C1(C(=O)C(=O)O)N=C(N)SC=1 |
| CAS DataBase Reference | 73150-67-1(CAS DataBase Reference) |
| FDA UNII | B8S9EKV7AU |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
2-(2-Aminothiazol-4-yl)glyoxylic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A630205 | 2-Amino-4-thiazoleglyoxylicAcid | 73150-67-1 | 5g | $595 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA29941 | 2-(2-Aminothiazol-4-yl) glyoxylic acid | 73150-67-1 | 5G | $700 | 2021-12-16 | Buy |
| AK Scientific | K980 | 2-(2-Aminothiazol-4-yl)glyoxylicacid | 73150-67-1 | 10g | $725 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA29941 | 2-(2-Aminothiazol-4-yl) glyoxylic acid | 73150-67-1 | 250mg | $125 | 2021-12-16 | Buy |
| AK Scientific | K980 | 2-(2-Aminothiazol-4-yl)glyoxylicacid | 73150-67-1 | 1g | $158 | 2021-12-16 | Buy |
2-(2-Aminothiazol-4-yl)glyoxylic acid Chemical Properties,Uses,Production
Uses
2-Amino-4-thiazoleglyoxylic Acid is an intermediate in synthesizing (6R,7R)-7-(2-(2-Aminothiazol-4-yl)-2-oxoacetamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (A630310), which is used in the preparation of Cephalosporin C (C258750), an antibiotic used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis.
Synthesis
89721-50-6
73150-67-1
Under ice bath cooling conditions, 10.1 g of methyl 2-(2-aminothiazol-4-yl)thioacetoxy S-acid (CAS: 89721-50-6) was mixed with 80 mL of water, followed by the addition of 10.6 g of sodium carbonate. The reaction mixture was stirred continuously for 1 h at a maintained ice bath temperature. Upon completion of the reaction, the pH of the reaction mixture was adjusted to 2.5 at the same temperature using 6 N hydrochloric acid. the precipitated crystals were collected by filtration, washed with deionized water and subsequently dried to afford 6.2 g (67.8% yield) of 2-(2-aminothiazol-4-yl)glyoxalic acid with a melting point of more than 200°C. The infrared spectra of the product (KBr pressed slice) showed a νC=O absorption peak at 1660 cm?1.
References
[1] Patent: US4563534, 1986, A
2-(2-Aminothiazol-4-yl)glyoxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-(2-Aminothiazol-4-yl)glyoxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29801 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 12272 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49982 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20193 | 58 |
View Lastest Price from 2-(2-Aminothiazol-4-yl)glyoxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 2-(2-Aminothiazol-4-yl)glyoxylic acid
73150-67-1
|
US $3.00 / KG | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 2-(2-Aminothiazol-4-yl)glyoxylic acid
73150-67-1
- US $3.00 / KG
- 98%
- Career Henan Chemical Co
