DIGITOXIGENIN
- CAS No.
- 143-62-4
- Chemical Name:
- DIGITOXIGENIN
- Synonyms
- echujetin;evonogenin;NSC 407806;cerberigenin;THEVETIGENIN;igitoxigenin;DIGITOXYGENIN;DIGITOXIGENIN;digitoxigenine;Digitoxigenin >
- CBNumber:
- CB8187462
- Molecular Formula:
- C23H34O4
- Molecular Weight:
- 374.51
- MDL Number:
- MFCD00003687
- MOL File:
- 143-62-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Digitoxigenin non-ionic | D9404 | 10mg | $101 |
| Digitoxigenin non-ionic | D9404 | 100mg | $618 |
| Digitoxigenin >97.0%(HPLC) | D0541 | 10mg | $220 |
| Digitoxigenin ≥95% | 18229 | 5mg | $49 |
| Digitoxigenin ≥95% | 18229 | 10mg | $86 |
| More product size | |||
| Melting point | 253-255 °C (dec.)(lit.) |
|---|---|
| alpha | D17 +19.1° (c = 1.36 in methanol) |
| Boiling point | 423.5°C (rough estimate) |
| Density | 1.0284 (rough estimate) |
| refractive index | 1.4433 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml |
| form | powder to crystal |
| pka | 14.93±0.70(Predicted) |
| color | White to Almost white |
| optical activity | +2323 (c 0.5, CHCl3) |
| Water Solubility | 11.24mg/L(30 ºC) |
| Merck | 14,3162 |
| BRN | 95448 |
| Stability | Hygroscopic |
| InChIKey | XZTUSOXSLKTKJQ-CESUGQOBSA-N |
| SMILES | [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@]([H])(CC[C@]34O)C5=CC(=O)OC5)[C@@]1(C)CC[C@H](O)C2 |
| LogP | 2.640 |
| CAS DataBase Reference | 143-62-4(CAS DataBase Reference) |
| FDA UNII | S63WOD4VOL |
| UNSPSC Code | 12161900 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 45 | |||||||||
| RIDADR | UN 3462 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FH4975000 | |||||||||
| HS Code | 2938.90.0000 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Oral | |||||||||
| Toxicity | cat,LDLo,intravenous,254ug/kg (0.254mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITING,Journal of the American Pharmaceutical Association. Vol. 27, Pg. 189, 1938. | |||||||||
| NFPA 704 |
|
DIGITOXIGENIN price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D9404 | Digitoxigenin non-ionic | 143-62-4 | 10mg | $101 | 2024-03-01 | Buy |
| Sigma-Aldrich | D9404 | Digitoxigenin non-ionic | 143-62-4 | 100mg | $618 | 2024-03-01 | Buy |
| TCI Chemical | D0541 | Digitoxigenin >97.0%(HPLC) | 143-62-4 | 10mg | $220 | 2026-04-30 | Buy |
| Cayman Chemical | 18229 | Digitoxigenin ≥95% | 143-62-4 | 5mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 18229 | Digitoxigenin ≥95% | 143-62-4 | 10mg | $86 | 2026-04-30 | Buy |
DIGITOXIGENIN Chemical Properties,Uses,Production
Uses
Cardiotonic;Na+ K+ ATPase inhibitor
Definition
ChEBI: Digitoxigenin is a 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22). It is a 3beta-hydroxy steroid and a 14beta-hydroxy steroid. It derives from a hydride of a 5beta-cardanolide.
Purification Methods
Dissolve digitoxigenin in EtOAc, wash it with H2O, dry it (Na2SO4), evaporate and recrystallise it from 40% aqueous EtOH or aqueous MeOH then EtOAc/Et2O. The UV has max at 218nm ( 14,500 M-1cm-1). The 3-acetate crystallises from Me2CO/Et2O with m 222-227o, [] D 20 +21o (c 1, CHCl3). [Wyss et al. Helv Chim Acta 43 644 1960, Cruz et al. J Org Chem 4 2 3580 1977, Beilstein 18 IV 1468.]
DIGITOXIGENIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30227 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 10000 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49968 | 58 |
View Lastest Price from DIGITOXIGENIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-22 | Digitoxigenin
143-62-4
|
US $159.00-623.00 / mg | 10g | TargetMol Chemicals Inc. | |||
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2024-04-12 | DIGITOXIGENIN
143-62-4
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd |
-

- Digitoxigenin
143-62-4
- US $159.00-623.00 / mg
- TargetMol Chemicals Inc.
-

- DIGITOXIGENIN
143-62-4
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd





