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Ethyl 3,3-Diethoxypropionate

Ethyl 3,3-Diethoxypropionate structure

CAS No.: 10601-80-6

Chemical Name:: Ethyl 3,3-Diethoxypropionate

Synonyms: ETHYL 3,3-DIETHOXYPROPANOATE;DEPE;3,3-Diethoxypropanoic acid;3,3-DIETHOXYPROPIONIC ACID ETHYL ESTER;malonaldehydic acid ethyl ester diethylacetal;INDIP-015;3-diethoxypropionate;3,3-diethoxypentanoate;Regadenoson Impurity 15;(2-CHLORO-ETHOXY)-ACETIC

CBNumber:: CB8188641

Molecular Formula:: C9H18O4

Molecular Weight:: 190.24

MDL Number:: MFCD00009865

MOL File:: 10601-80-6.mol

MSDS File:: SDS

Last updated:2026-05-28 04:22:52

Product description	Number	Pack Size	Price
Ethyl 3,3-diethoxypropionate 90%, technical grade	414476	10ml	$72.1
Ethyl 3,3-diethoxypropionate 90%, technical grade	414476	50ml	$255
Ethyl 3,3-Diethoxypropionate >95.0%(GC)	D1962	25mL	$86
Ethyl 3,3-Diethoxypropionate >95.0%(GC)	D1962	100mL	$221
Ethyl 3,3-diethoxypropionate Asreported	274854	25g	$375
More product size

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Ethyl 3,3-Diethoxypropionate Properties

Melting point	200-202 °C
Boiling point	92-93 °C/13 mmHg (lit.)
Density	0.978 g/mL at 25 °C (lit.)
refractive index	n20/D 1.411(lit.)
Flash point	184 °F
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Liquid
color	Clear colorless
BRN	1772110
Stability	Hygroscopic
InChI	InChI=1S/C9H18O4/c1-4-11-8(10)7-9(12-5-2)13-6-3/h9H,4-7H2,1-3H3
InChIKey	SIALOQYKFQEKOG-UHFFFAOYSA-N
SMILES	C(OCC)(=O)CC(OCC)OCC
LogP	2.260 (est)
CAS DataBase Reference	10601-80-6(CAS DataBase Reference)
FDA UNII	949D397DXS
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227

Precautionary statements

P210e-P280a-P370+P378a-P501a-P210-P280-P370+P378-P403+P235-P501

PPE

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Safety Statements

23-24/25

WGK Germany

10-21

HS Code

29189900

Storage Class

10 - Combustible liquids

NFPA 704

	2
0		0

Ethyl 3,3-Diethoxypropionate price More Price(87)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	414476	Ethyl 3,3-diethoxypropionate 90%, technical grade	10601-80-6	10ml	$72.1	2026-04-30	Buy
Sigma-Aldrich	414476	Ethyl 3,3-diethoxypropionate 90%, technical grade	10601-80-6	50ml	$255	2026-04-30	Buy
TCI Chemical	D1962	Ethyl 3,3-Diethoxypropionate >95.0%(GC)	10601-80-6	25mL	$86	2026-04-30	Buy
TCI Chemical	D1962	Ethyl 3,3-Diethoxypropionate >95.0%(GC)	10601-80-6	100mL	$221	2026-04-30	Buy
Usbiological	274854	Ethyl 3,3-diethoxypropionate Asreported	10601-80-6	25g	$375	2026-06-03	Buy

Product number	Packaging	Price	Buy
414476	10ml	$72.1	Buy
414476	50ml	$255	Buy
D1962	25mL	$86	Buy
D1962	100mL	$221	Buy
274854	25g	$375	Buy

Ethyl 3,3-Diethoxypropionate Chemical Properties,Uses,Production

Description

Ethyl 3,3-diethoxypropionate is an organic compound that is synthesized from the reaction of diethyl malonate and chloroacetic acid in the presence of a base catalyst. This product has been shown to be an effective inhibitor of mitochondrial cytochrome c oxidase in vitro studies. Ethyl 3,3-diethoxypropionate also has been found to inhibit quinoline derivatives, such as erythromycin and tetracycline, which are involved in bacterial DNA synthesis. Furthermore, this product inhibits β-unsaturated aldehydes and allylation.

Chemical Properties

clear colorless liquid

Uses

Ethyl 3,3-diethoxypropionate participates in the Yb(OTf)3 catalyzed synthesis of dihydropyridines (DHPs).

Synthesis Reference(s)

The Journal of Organic Chemistry, 47, p. 2216, 1982 DOI: 10.1021/jo00132a055
Synthesis, p. 274, 1988 DOI: 10.1055/s-1988-27541

Ethyl 3,3-Diethoxypropionate synthesis

Synthesis of Ethyl 3,3-Diethoxypropionate from Ethanol and 4-ethoxy-1,1,1-trichloro-3-buten-2-one

Ethyl 3,3-Diethoxypropionate Preparation Products And Raw materials

Raw materials

ZINC Triethyl orthoformate Chlorotrimethylsilane Ethyl bromoacetate Diethyl ether

(E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one 4-ethoxy-1,1,1-trichloro-3-buten-2-one

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Preparation Products

2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE 2-(TRIFLUOROMETHYL)PYRIMIDIN-5-AMINE ETHYL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 2-DIMETHYLAMINO-PYRIMIDINE-5-CARBOXYLIC ACID

(2-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL)METHANOL 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLIC ACID 4-CHLORO-2-METHYLPYRIMIDINE (2-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL)METHANAMINE 2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE

2-Aminopyrimidine-5-carboxylic acid 2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE Triethyl 1,3,5-benzenetricarboxylate 3,3-DIETHOXY-PROPIONIC ACID 3-ETHOXYACRYLIC ACID

3,3-Diethoxypropionitrile

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Ethyl 3,3-Diethoxypropionate Suppliers

Global( 381)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Fullone Chemical Co., Ltd.	+86-13328197671 +86-13861172460	sales@borenchem.cn	China	1055	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20582	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5228	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55

Supplier	Advantage
Changzhou Fullone Chemical Co., Ltd.	58
Hebei Yanxi Chemical Co., Ltd.	58
Dideu Industries Group Limited	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from Ethyl 3,3-Diethoxypropionate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-28	ETHYL 3,3-DIETHOXYPROPIONATE 10601-80-6	$10.00-130.00	10kg	99%	100000kg	Hebei Chuanghai Biotechnology Co,.LTD
2025-11-18	Ethyl 3,3-Diethoxypropionate 10601-80-6	$1.10	1g	99.9%	100 Tons Min	Dideu Industries Group Limited
2025-06-27	ETHYL 3,3-DIETHOXYPROPIONATE 10601-80-6		1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

ETHYL 3,3-DIETHOXYPROPIONATE
10601-80-6
$10.00-130.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

Ethyl 3,3-Diethoxypropionate
10601-80-6
$1.10
99.9%
Dideu Industries Group Limited

ETHYL 3,3-DIETHOXYPROPIONATE
10601-80-6
99%
Hebei Chuanghai Biotechnology Co., Ltd

Ethyl 3,3-Diethoxypropionate Spectrum

ETHYL 3,3-DIETHOXYPROPIONATE(10601-80-6)MS ETHYL 3,3-DIETHOXYPROPIONATE(10601-80-6)¹HNMR ETHYL 3,3-DIETHOXYPROPIONATE(10601-80-6)¹³CNMR ETHYL 3,3-DIETHOXYPROPIONATE(10601-80-6)IR1

10601-80-6(Ethyl 3,3-Diethoxypropionate)Related Search:

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Propanoic acid, 3,3-diethoxy-, ethyl ester ETHYL 3,3-DIETHOXYPROPIONATE ETHYL 3,3-DIETHOXYPROPIONATE, TECH., 90% 3,3-Diethoxypropanoic acid, ethyl ester malonaldehydic acid diethyl acetal ethyl ester malonaldehydic acid ethyl ester diethylacetal Ethy 3,3-diethoxypropanoate Ethyl 3,3-diethoxypropionate ,95% Ethyl 3,3-diethoxypropionate ,98% Ethyl 3,3-diethoxypropion... 3,3-diethoxypentanoate Ethyl 3,3-diethoxypropanoate, 98% 100ML Ethyl 3,3-diethoxypropanoate, 98% 25ML Ethyl 3,3-diethoxypropanoate, 98% 5ML Ethyl 3,3-diethoxypropanoate,98% Diethoxypropionic Acid Ethyl Es Ethl3,3-diethoxypropionate Ethyl 3,3-diethoxypropionate 90%, technical grade 3, 3-2 ethoxy ethyl propionate INDIP-015 ETHYL 3,3-DIETHOXYPROPIOTE 3-diethoxypropionate Ethyl 3,3-diethoxypropanoate 97% Regadenoson Impurity 15 Ethyl-3,3-diethoxypropionat Ethyl3,3-Diethoxypropionate> 3,3-DIETHOXYPROPANOIC ACID CAS 10601-80-6 (2-CHLORO-ETHOXY)-ACETIC Propanoic acid, 3,3-diethoxy-, ethyl ester (9CI, ACI) 3,3-diethoxy-Propanoic acid ethyl ester (9CI ACI) 3,3-Diethoxypropanoic acid 3,3-DIETHOXYPROPIONIC ACID ETHYL ESTER DEPE ETHYL 3,3-DIETHOXYPROPANOATE 10601-80-6 10610-80-6 C2H5O2CHCH2CO2C2H5 C9H18O4 Carbonyl Compounds C8 to C9 Esters Organic Building Blocks Building Blocks Pyridine Pharmaceutical Intermediates bc0001