PROTOPORPHYRINATO ZINC
- CAS No.
- 15442-64-5
- Chemical Name:
- PROTOPORPHYRINATO ZINC
- Synonyms
- ZnPP;PROTOPORPHYRINATO ZINC;Protoporphyrin IX Zinc;Zinc protoporphyrin trihydrate;Zinc Protoporphyrin, 10 mM in DMSO;Zinc protoporphyrin trihydrate, 95+%;PROTOPORPHYRINATO ZINC ISO 9001：2015 REACH;Zinc Protoporphyrin IX DISCONTINUED, offer Z439970;Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem;Zinc(II) 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate
- CBNumber:
- CB8208833
- Molecular Formula:
- C34H31N4O4Zn-
- Molecular Weight:
- 625.03
- MDL Number:
- MFCD00011612
- MOL File:
- 15442-64-5.mol
| Product description | Number | Pack Size | Price |
| Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. | 691550-M | 25mg | $103 |
| Protoporphyrin IX zinc(II) guanylate cyclase inhibitor | 282820 | 50mg | $227 |
| Protoporphyrin IX zinc(II) guanylate cyclase inhibitor | 282820 | 250mg | $739.44 |
| Zinc Protoporphyrin-9 ≥98% | 14483 | 10mg | $34 |
| Zinc Protoporphyrin-9 ≥98% | 14483 | 25mg | $71 |
| RTECS | ZG9210300 |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO : 50 mg/mL (79.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Crystalline |
| color | Dark red to purple |
| Water Solubility | Insoluble in water. Soluble in ethanol, and DMSO, pyridine, or dimethyl formamide. |
| ε(extinction coefficient) |
≥10000 at 585-591nm in pyridine ≥12000 at 548-554nm in pyridine ≥135000 at 423-429nm in pyridine |
| λmax | 426 nm |
| Stability | Hygroscopic |
| InChIKey | FUTVBRXUIKZACV-RGGAHWMASA-K |
| SMILES | C(C1C(=C2C=C3C(C=C)=C(C)C4C=C5C(C=C)=C(C)C6=CC7C(C)=C(CCC(=O)[O-])C8N=7[Zn+2]([N-]56)(N3=4)[N-]2C=1C=8)C)CC(=O)[O-].[H+] |
| FDA UNII | LNV3FKZ7GR |
| EPA Substance Registry System | Zincate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24]-, dihydrogen, (SP-4-2)- (15442-64-5) |
| UNSPSC Code | 12171500 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
PROTOPORPHYRINATO ZINC price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 691550-M | Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. | 15442-64-5 | 25mg | $103 | 2025-07-31 | Buy |
| Sigma-Aldrich | 282820 | Protoporphyrin IX zinc(II) guanylate cyclase inhibitor | 15442-64-5 | 50mg | $227 | 2025-07-31 | Buy |
| Sigma-Aldrich | 282820 | Protoporphyrin IX zinc(II) guanylate cyclase inhibitor | 15442-64-5 | 250mg | $739.44 | 2025-07-31 | Buy |
| Cayman Chemical | 14483 | Zinc Protoporphyrin-9 ≥98% | 15442-64-5 | 10mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 14483 | Zinc Protoporphyrin-9 ≥98% | 15442-64-5 | 25mg | $71 | 2024-03-01 | Buy |
PROTOPORPHYRINATO ZINC Chemical Properties,Uses,Production
Uses
Zinc Protoporphyrin is a metabolite formed during biosynthesis and is used to evaluate iron nutrition and metabolism.
General Description
A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. Inhibits soluble guanylyl cyclase and produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50 = 800 nM, 4 μM, and 5 μM for nNOS, iNOS, and eNOS, respectively). Inhibits relaxation induced by acetylcholine, ANP, and VIP in isolated rat aorta. Blocks interleukin-1 and prevents induction of long-term potentiation. Also useful as an indicator of iron-deficient erythropoiesis. Does not cross the blood-brain barrier.
Biological Activity
Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.
Biochem/physiol Actions
Primary Targetheme oxygenase
in vivo
Zinc Protoporphyrin (12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o.; from day 7 to 19) exerts dose-dependent antitumor effects manifested by the retardation of tumor growth[3].
| Animal Model: | BALB/c mice inoculated with C-26 cells[3] |
| Dosage: | 12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o. |
| Administration: | IP or PO; from day 7 to 19 |
| Result: | Exerted dose-dependent antitumor effects manifested by the retardation of tumor growth. |
IC 50
Human Endogenous Metabolite
PROTOPORPHYRINATO ZINC Preparation Products And Raw materials
Raw materials
Preparation Products
PROTOPORPHYRINATO ZINC Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19282 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39042 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43416 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53899 | 58 |
View Lastest Price from PROTOPORPHYRINATO ZINC manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | Zinc Protoporphyrin
15442-64-5
|
US $42.00-64.00 / mg | 98.31% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-02-02 | Zinc Protoporphyrin
15442-64-5
|
US $42.00-64.00 / mg | 98.31% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-11-18 | PROTOPORPHYRINATO ZINC
15442-64-5
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- Zinc Protoporphyrin
15442-64-5
- US $42.00-64.00 / mg
- 98.31%
- TargetMol Chemicals Inc.
-
- Zinc Protoporphyrin
15442-64-5
- US $42.00-64.00 / mg
- 98.31%
- TargetMol Chemicals Inc.
-
- PROTOPORPHYRINATO ZINC
15442-64-5
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
