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ChemicalBook >> CAS DataBase List >>2-AMINO-4,4'-DICHLORODIPHENYL ETHER

2-AMINO-4,4'-DICHLORODIPHENYL ETHER

2-AMINO-4,4'-DICHLORODIPHENYL ETHER Structure
2-AMINO-4,4'-DICHLORODIPHENYL ETHER structure
CAS No.
121-27-7
Chemical Name:
2-AMINO-4,4'-DICHLORODIPHENYL ETHER
Synonyms
5-CHLORO-2-(4-CHLOROPHENOXY)ANILINE;AURORA KA-6780;C.I.37075(base);Fast Red FR Base;Diazo Fast Red FR;Fast Red Salt FRN.;C.I.Azoic Diazo Component 33;5-Chloro-2-(4-Clorophenoxy)Aniline;C.I.Azoic Diazo Component 33(base);4,4'-Dichloro-2-aminodiphenyl ether
CBNumber:
CB8209148
Molecular Formula:
C12H9Cl2NO
Molecular Weight:
254.11
MDL Number:
MFCD00027391
MOL File:
121-27-7.mol
Last updated:2026-07-01 20:51:29
Product description Number Pack Size Price
2-Amino-4,4'-dichlorodiphenyl Ether >98.0%(GC)(T) A2225 5g $113
2-Amino-4,4'-dichlorodiphenyl Ether >98.0%(GC)(T) A2225 25g $369
5-Chloro-2-(4-chlorophenoxy)aniline ≥98% CS-0010207 25g $169
5-Chloro-2-(4-chlorophenoxy)aniline ≥98% CS-0010207 25g $169
5-Chloro-2-(4-chlorophenoxy)aniline >97% OR2816 250mg $21
More product size
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2-AMINO-4,4'-DICHLORODIPHENYL ETHER Properties

Melting point 61.0 to 65.0 °C
Boiling point 234°C/27mmHg(lit.)
Density 1.364±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 2.99±0.10(Predicted)
form powder to crystal
color White to Yellow to Orange
CAS DataBase Reference 121-27-7(CAS DataBase Reference)
FDA UNII LK5QE26HRU
EPA Substance Registry System 4,4'-Dichloro-2-aminodiphenyl ether (121-27-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  2922290090
NFPA 704
0
1 0

2-AMINO-4,4'-DICHLORODIPHENYL ETHER price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2225 2-Amino-4,4'-dichlorodiphenyl Ether >98.0%(GC)(T) 121-27-7 5g $113 2024-03-01 Buy
TCI Chemical A2225 2-Amino-4,4'-dichlorodiphenyl Ether >98.0%(GC)(T) 121-27-7 25g $369 2024-03-01 Buy
ChemScene CS-0010207 5-Chloro-2-(4-chlorophenoxy)aniline ≥98% 121-27-7 25g $169 2026-06-04 Buy
ChemScene CS-0010207 5-Chloro-2-(4-chlorophenoxy)aniline ≥98% 121-27-7 25g $169 2026-06-04 Buy
Apolloscientific OR2816 5-Chloro-2-(4-chlorophenoxy)aniline >97% 121-27-7 250mg $21 2026-06-04 Buy
Product number Packaging Price Buy
A2225 5g $113 Buy
A2225 25g $369 Buy
CS-0010207 25g $169 Buy
CS-0010207 25g $169 Buy
OR2816 250mg $21 Buy

2-AMINO-4,4'-DICHLORODIPHENYL ETHER Chemical Properties,Uses,Production

Chemical Properties

Brown solid

Synthesis

4-Chloro-1-(4-chlorophenoxy)-2-nitrobenzene

135-12-6

2-AMINO-4,4'-DICHLORODIPHENYL ETHER

121-27-7

4,4'-Dichloro-2-nitro-diphenyl ether (12.0 g, 42.2 mmol) was used as a raw material, which was mixed with FeCl3 (702 mg, 4.33 mmol) and activated charcoal (3.70 g) in MeOH (360 mL) and stirred at 50 °C. Hydrazine monohydrate (7.00 mL, 144 mmol) was added slowly over 10 minutes, followed by heating the reaction mixture to reflux and stirring for 1 hour. After completion of the reaction, the mixture was cooled, filtered through diatomaceous earth and the filter cake was washed with MeOH. The filtrate was concentrated under reduced pressure to give an oily residue. This residue was dissolved with EtOAc, and the organic layer was washed sequentially with saturated aqueous NaHCO3 and brine, and then dried with Na2SO4. After filtration to remove the insoluble matter, the filtrate was concentrated under reduced pressure to give 5-chloro-2-(4-chlorophenoxy)-aniline (8) (10.6 g, 99% yield) as a colorless solid with a melting point of 59-61 °C. The product was characterized by 1H NMR (400 MHz, CDCl3), 13C NMR (100 MHz, CDCl3) and LC-MS (ESI) to confirm its structure.

References

[1] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 15, p. 4952 - 4969
[2] Patent: CN107353185, 2017, A. Location in patent: Paragraph 0031; 0034; 0036
[3] Journal of the Chemical Society, 1929, p. 521
[4] Journal of the Chemical Society, 1931, p. 529,533
[5] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 9, p. 323

2-AMINO-4,4'-DICHLORODIPHENYL ETHER synthesis

135-12-6
121-27-7
Synthesis of 2-AMINO-4,4'-DICHLORODIPHENYL ETHER from 4-Chloro-1-(4-chlorophenoxy)-2-nitrobenzene

2-AMINO-4,4'-DICHLORODIPHENYL ETHER Preparation Products And Raw materials

Raw materials

Iron filings Nitrogen Formic acid 4-Chloro-1-(4-chlorophenoxy)-2-nitrobenzene 4-Chlorophenol
2,5-Dichloronitrobenzene 1,4-Dichlorobenzene Acetic acid Ferric chloride Hydrazine hydrate

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Preparation Products

244TRICHLORODIPHENYLETHER

2-AMINO-4,4'-DICHLORODIPHENYL ETHER Suppliers

Global( 131)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Dideu Industries Group Limited 		+86-86-15536356810 +8617392712697 1022@dideu.com China 29065 58
Baoji Guokang Healthchem co.,ltd 		+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9414 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shenzhen Nexconn Pharmatechs Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
SIMAGCHEM CORP 		58
Dideu Industries Group Limited 		58
Baoji Guokang Healthchem co.,ltd 		58

View Lastest Price from 2-AMINO-4,4'-DICHLORODIPHENYL ETHER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-4,4'-DICHLORODIPHENYL ETHER pictures 2026-07-01 2-AMINO-4,4'-DICHLORODIPHENYL ETHER
121-27-7
 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
2-AMINO-4,4'-DICHLORODIPHENYL ETHER pictures 2026-03-20 2-AMINO-4,4'-DICHLORODIPHENYL ETHER
121-27-7
 $1.00 1PCS 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Amino-4,4'-dichloro-diphenyl ether pictures 2025-04-04 2-Amino-4,4'-dichloro-diphenyl ether
121-27-7
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

121-27-7(2-AMINO-4,4'-DICHLORODIPHENYL ETHER)Related Search:

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5-chloro-2-(4-chlorophenoxy)-benzenamin 5-chloro-2-(4-chlorophenoxy)-Benzenamine 5-CHLORO-2-(4-CHLOROPHENOXY)ANILINE AURORA KA-6780 Benzenamine,5-chloro-2-(4-chlorophenoxy)- C.I.Azoic Diazo Component 33 Diazo Fast Red FR Fast Red FR Base Fast Red Salt FRN. 5-Chloro-2-(4-Clorophenoxy)Aniline C.I.37075(base) C.I.Azoic Diazo Component 33(base) 4,4'-Dichloro-2-aminodiphenyl ether 2-(4-chlorophenoxy)-5-chlorobenzenamine 2-Amino-4,4'-dichlorodiphenyl Ether > 2-AMINO-4,4'-DICHLORODIPHENYL ETHER ISO 9001：2015 REACH 2-Amino-4,4'-dichlorodiphenyl Ether 121-27-7 Phenyls & Phenyl-Het Amines Phenyls & Phenyl-Het