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4-Bromo-3-nitroanisole

4-Bromo-3-nitroanisole structure

CAS No.: 5344-78-5

Chemical Name:: 4-Bromo-3-nitroanisole

Synonyms: TIMTEC-BB SBB009974;4-Brom-3-nitroanisol;4-Bromo-3-nitroanisol;4-BROMO-3-NITROANISOLE;4-Bromo-3-nitroanlsole;4-BROMO-3-NITROTHIOANISOLE;4-Bromo-3-nitroanisole >4-bromo-3-nitrobenzyl ether;3-nitro-4-bromobenzyl ether;4-Methoxy-2-nitrobromobenzene

CBNumber:: CB8211332

Molecular Formula:: C7H6BrNO3

Molecular Weight:: 232.03

MDL Number:: MFCD00051511

MOL File:: 5344-78-5.mol

MSDS File:: SDS

Last updated:2025-08-25 18:08:31

Product description	Number	Pack Size	Price
4-Bromo-3-nitroanisole 97%	338737	5g	$31
4-Bromo-3-nitroanisole >96.0%(GC)	B3420	5g	$39
4-Bromo-3-nitroanisole >96.0%(GC)	B3420	25g	$127
4-Bromo-3-nitroanisole	B688138	5g	$75
1-Bromo-4-methoxy-2-nitrobenzene	CS-W008002	25g	$30
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4-Bromo-3-nitroanisole Properties

Melting point	32-34 °C (lit.)
Boiling point	153-154 °C/13 mmHg (lit.)
Density	1.8134 (rough estimate)
refractive index	1.6090 (estimate)
Flash point	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	powder to lump to clear liquid
color	White or Colorles to Yellow to Orange
BRN	2446617
InChI	InChI=1S/C7H6BrNO3/c1-12-5-2-3-6(8)7(4-5)9(10)11/h2-4H,1H3
InChIKey	KCOBIBRGPCFIGF-UHFFFAOYSA-N
SMILES	C1(Br)=CC=C(OC)C=C1[N+]([O-])=O
CAS DataBase Reference	5344-78-5(CAS DataBase Reference)
NIST Chemistry Reference	4-Bromo-3-nitroanisole(5344-78-5)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25

WGK Germany

HS Code

29093090

NFPA 704

	1
2		0

4-Bromo-3-nitroanisole price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	338737	4-Bromo-3-nitroanisole 97%	5344-78-5	5g	$31	2025-07-31	Buy
TCI Chemical	B3420	4-Bromo-3-nitroanisole >96.0%(GC)	5344-78-5	5g	$39	2025-07-31	Buy
TCI Chemical	B3420	4-Bromo-3-nitroanisole >96.0%(GC)	5344-78-5	25g	$127	2025-07-31	Buy
TRC	B688138	4-Bromo-3-nitroanisole	5344-78-5	5g	$75	2021-12-16	Buy
ChemScene	CS-W008002	1-Bromo-4-methoxy-2-nitrobenzene	5344-78-5	25g	$30	2021-12-16	Buy

Product number	Packaging	Price	Buy
338737	5g	$31	Buy
B3420	5g	$39	Buy
B3420	25g	$127	Buy
B688138	5g	$75	Buy
CS-W008002	25g	$30	Buy

4-Bromo-3-nitroanisole Chemical Properties,Uses,Production

Chemical Properties

Yellow to dark brown solid

Uses

4-Bromo-3-nitroanisole was used in the synthesis of:

4-bromo-5-methoxyaniline
2-(4-methoxy-2-nitrophenylsulfanyl)benzoic acid
4-(1-diethylamino-4-pentylamino)-3-nitrochlorobenzene

General Description

FT-IR and FT-Raman spectra of 4-bromo-3-nitroanisole have been studied.

Synthesis

96-96-8

5344-78-5

The general procedure for the synthesis of 4-bromo-3-nitroanisole from ice-dyed diazo component 1 was as follows: a solution of sodium nitrite (11.8 g) in water (28 mL) was slowly added dropwise to a 40% solution of nitroaniline (125 mmol) in hydrobromic acid (110 g) over a period of 0.5 h. The temperature of the reaction was maintained at 10 °C. The reaction mixture was stirred at 0-10 °C for 40 min and then filtered. Subsequently, the filtrate was added dropwise to a purple solution of copper(I) bromide (209 mmol) in hydrobromic acid (74 mL) at 0 °C over a period of 1 hour. The reaction mixture was gradually warmed to room temperature and held for 30 min, then warmed to 60 °C for 0.5 h. The reaction was finally heated and refluxed for 1 h. The reaction was carried out at a temperature of 0.5 °F to 0.5 °F. After completion of the reaction, the mixture was partitioned between water (2.0 L) and dichloromethane (600 mL) and the aqueous phase was then extracted with dichloromethane (300 mL). All organic layers were combined and washed sequentially with 10% sodium hydroxide solution (200 mL), water (600 mL), 10% hydrochloric acid (300 mL) and water (600 mL). The organic layer was dried over magnesium sulfate and concentrated to give 4-bromo-3-nitroanisole in 83% yield as a yellow oil.

References

[1] Journal of Organic Chemistry, 1989, vol. 54, # 25, p. 5856 - 5866
[2] Journal of Organic Chemistry, 1992, vol. 57, # 24, p. 6380 - 6382
[3] Journal of the American Chemical Society, 1994, vol. 116, # 26, p. 11797 - 11810
[4] Tetrahedron Letters, 2006, vol. 47, # 16, p. 2739 - 2742
[5] Tetrahedron, 2010, vol. 66, # 37, p. 7418 - 7422

4-Bromo-3-nitroanisole synthesis

Synthesis of 4-Bromo-3-nitroanisole from 4-Methoxy-2-nitrobenzoic acid

4-Bromo-3-nitroanisole Preparation Products And Raw materials

Raw materials

4-Methoxy-2-nitrobenzoic acid 4-Chloro-3-nitroanisole 4-METHOXY-2-NITROACETANILIDE 4-METHOXY-3-NITROANILINE Cuprous bromide

Hydrogen bromide Azoic Diazo Component 1 Sodium nitrite Methacetin

1of2

Preparation Products

4-BROMO-2-NITROANISOLE 6-Methoxyindole Benzenamine, 2-cyclopropyl-5-methoxy- 7-METHOXY-2-PHENYL-QUINOLIN-4-OL 7-BROMO-4-METHOXYINDOLE

4-Bromo-3-nitroanisole Suppliers

Global( 282)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Springchem New Material Technology Co.,Limited	+86-021-62885108 +8613917661608	info@spring-chem.com	China	2068	57
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13595	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21610	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	969	58

Supplier	Advantage
Springchem New Material Technology Co.,Limited	57
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Changzhou Ansciep Chemical Co., Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Shanghai Worldyang Chemical Co.,Ltd.	58

View Lastest Price from 4-Bromo-3-nitroanisole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-17	4-Bromo-3-nitroanisole 5344-78-5	US $0.00 / KG	25KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-11-19	4-Bromo-3-nitroanisole 5344-78-5	US $0.00 / kg	1kg	99.0%	1000kg	Shanghai Joiny Pharmaceutical Co.,LTD
2025-08-26	4-Bromo-3-Nitroanisole 5344-78-5	US $0.00-0.00 / kg	1kg	99%	1	Jinan Ruitong Biotech Co., Ltd.

4-Bromo-3-nitroanisole
5344-78-5
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-Bromo-3-nitroanisole
5344-78-5
US $0.00 / kg
99.0%
Shanghai Joiny Pharmaceutical Co.,LTD

4-Bromo-3-Nitroanisole
5344-78-5
US $0.00-0.00 / kg
99%
Jinan Ruitong Biotech Co., Ltd.

4-Bromo-3-nitroanisole Spectrum

4-Bromo-3-nitroanisole(5344-78-5)¹HNMR 4-Bromo-3-nitroanisole(5344-78-5)IR 4-Bromo-3-nitroanisole(5344-78-5)Raman 4-Bromo-3-nitroanisole(5344-78-5)FT-IR

5344-78-5(4-Bromo-3-nitroanisole)Related Search:

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2-BROMO-4-NITROANISOLE,2-BROMO-4-NITROANISOLE 95% 3-BROMO-5-NITROANISOLE 3-Nitroanisole Nitrobenzene 3-Bromonitrobenzene

4-Nitroanisole 2-BROMO-5-NITROANISOLE Azoic Diazo Component 1

1of4

1-Bromo-4-methoxy-2-nitrobenzene 4-Bromo-3-nitroanisol Benzene, 1-bromo-4-methoxy-2-nitro- 4-BROMO-3-NITROTHIOANISOLE 4-BROMO-3-NITROANISOLE TIMTEC-BB SBB009974 4-bromo-3-nitrobenzyl ether 4-Methoxy-2-nitrobromobenzene 1-Bromo-2-nitro-4-methoxybenzene 1-Nitro-2-bromo-5-methoxybenzene 4-Methoxy-2-nitrophenyl bromide 1-((4-((E)-2-nitrovinyl)phenoxy)methyl)benzene 4-Bromo-3-nitroanlsole 4-Bromo-3-nitroanisole > 4-Brom-3-nitroanisol 3-nitro-4-bromobenzyl ether 5344-78-5 Organic Building Blocks Nitrogen Compounds Nitro Compounds Building Blocks ARYL HALIDE Phenyls & Phenyl-Het Nitro Compounds Nitrogen Compounds Organic Building Blocks blocks Bromides NitroCompounds Halides Phenyls & Phenyl-Het Anisole Anisoles, Alkyloxy Compounds & Phenylacetates Bromine Compounds Nitro Compounds