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2-bromo-5-methoxy-4-methylaniline

2-bromo-5-methoxy-4-methylaniline Structure
2-bromo-5-methoxy-4-methylaniline structure
CAS No.
532440-88-3
Chemical Name:
2-bromo-5-methoxy-4-methylaniline
Synonyms
2-bromo-5-methoxy-4-methylaniline;2-Bromo-5-methoxy-4-methyl-phenylamine;Benzenamine, 2-bromo-5-methoxy-4-methyl-
CBNumber:
CB82122252
Molecular Formula:
C8H10BrNO
Molecular Weight:
216.08
MDL Number:
MFCD11841053
MOL File:
532440-88-3.mol
Last updated:2026-05-28 03:41:21
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2-bromo-5-methoxy-4-methylaniline Properties

Melting point 75-77°
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Warning
Hazard statements  H302+H332-H311-H315-H319
Precautionary statements  P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P361-P405-P501c
HazardClass  IRRITANT
HS Code  2922290090

2-bromo-5-methoxy-4-methylaniline price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR947349 2-Bromo-5-methoxy-4-methylaniline 98% 532440-88-3 1g $89 2026-06-04 Buy
Apolloscientific OR947349 2-Bromo-5-methoxy-4-methylaniline 98% 532440-88-3 5g $268 2026-06-04 Buy
Apolloscientific OR947349 2-Bromo-5-methoxy-4-methylaniline 98% 532440-88-3 10g $482 2026-06-04 Buy
Activate Scientific AS44306 2-Bromo-5-methoxy-4-methylaniline 98% 532440-88-3 1g $106 2026-06-04 Buy
Activate Scientific AS44306 2-Bromo-5-methoxy-4-methylaniline 98% 532440-88-3 5g $285 2026-06-04 Buy
Product number Packaging Price Buy
OR947349 1g $89 Buy
OR947349 5g $268 Buy
OR947349 10g $482 Buy
AS44306 1g $106 Buy
AS44306 5g $285 Buy

2-bromo-5-methoxy-4-methylaniline Chemical Properties, Uses, Production

Synthesis

Sodium bicarbonate

144-55-8

3-METHOXY-4-METHYLANILINE

16452-01-0

2-bromo-5-methoxy-4-methylaniline

532440-88-3

General procedure for the synthesis of 2-bromo-5-methoxy-4-methylaniline from sodium bicarbonate and 3-methoxy-4-methylaniline: to a solution of 3-methoxy-4-methylaniline (8.19 g, 59.71 mmol) in dichloromethane (200 mL) was added tetrabutylammonium tribromide (28.79 g, 59.71 mmol) and the reaction mixture was stirred at room temperature for 2.5 hours. Upon completion of the reaction, aqueous sodium bicarbonate was added for neutralization and the organic layer was separated. The aqueous layer was further extracted with dichloromethane, and the organic phases were combined, washed sequentially with water and brine, dried with anhydrous magnesium sulfate, filtered and concentrated. The residue was purified by silica gel column chromatography (eluent: hexane solution of 20% ethyl acetate) to afford 11.05 g of 2-bromo-5-methoxy-4-methylaniline in 85% yield. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 2.09 (s, 3H), 3.75 (s, 3H), 3.95 (br s, 1H), 6.27 (s, 1H), 7.13 (s, 1H).

References

[1] Patent: US2003/144329, 2003, A1

2-bromo-5-methoxy-4-methylaniline synthesis

16452-01-0
532440-88-3
Synthesis of 2-bromo-5-methoxy-4-methylaniline from 3-Methoxy-4-methylaniline

2-bromo-5-methoxy-4-methylaniline Preparation Products And Raw materials

Raw materials

Sodium bicarbonate 3-Methoxy-4-methylaniline Tetrabutylammonium tribromide Ethyl acetate Dichloromethane
Hexane

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Preparation Products

2-bromo-5-methoxy-4-methylaniline Suppliers

Global Suppliers ( 41)
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
Changzhou Anxuan Chemical, Co., Ltd. 13912302692 sales@anxuanchem.com China 4824 58
BioPharmaMatrix,Inc. 0510-86010668 13395169561; sales@biopharmamatrix.com China 5019 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
changzhou ansciep chemical co., ltd. 0519-86305871 13961213398; tina@ansciepchem.com China 1626 58
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418684 +86-18949823763 sales@tnjchem.com China 25333 58
Win-Win chemical CO., Limited +86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14301 58
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 56
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Changzhou Anxuan Chemical, Co., Ltd. 58
BioPharmaMatrix,Inc. 55
Amadis Chemical Company Limited 58
Aikon International Limited 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
changzhou ansciep chemical co., ltd. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Win-Win chemical CO., Limited 58

2-bromo-5-methoxy-4-methylaniline Spectrum

2-bromo-5-methoxy-4-methylaniline(532440-88-3)1HNMR

532440-88-3 (2-bromo-5-methoxy-4-methylaniline) Related Search:

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Benzenamine, 6-bromo-3-methoxy-2-methyl-, hydrochloride (1:1)

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2-bromo-5-methoxy-4-methylaniline 2-Bromo-5-methoxy-4-methyl-phenylamine Benzenamine, 2-bromo-5-methoxy-4-methyl- 532440-88-3