ChemicalBook >> CAS DataBase List >>FMRF AMIDE

FMRF AMIDE

FMRF AMIDE structure

CAS No.: 152165-14-5

Chemical Name:: FMRF AMIDE

Synonyms: FMRF-NH2;FMRF AMIDE;PHE-MET-ARG-PHE-NH2;PHE-MET-ARG-PHE AMIDE;H-PHE-MET-ARG-PHE-NH2;FMRFAMIDE ACETATE SALT;FMRF-AMIDE 1 1/2ACOH 2H2O;H-PHE-MET-ARG-PHE-NH2 ACOH;PHE-MET-ARG-PHE-NH2: FMRF-NH2;H-Phe-Met-Arg-Phe-NH2 acetate

CBNumber:: CB8231121

Molecular Formula:: C29H42N8O4S

Molecular Weight:: 598.76

MDL Number:: MFCD00076625

MOL File:: 152165-14-5.mol

MSDS File:: SDS

Last updated:2025-06-18 16:39:22

Request For Quotation

FMRF AMIDE Properties

storage temp.	−20°C
Sequence	Phe-Met-Arg-Phe-NH2

SAFETY

Risk and Safety Statements

WGK Germany	3

FMRF AMIDE Chemical Properties,Uses,Production

Uses

Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons[1].

in vivo

Phe-Met-Arg-Phe, amide (FMRFamide) acetate stimulates growth hormone secretion in conscious OVX rats. The presence of Phe-Met-Arg-Phe, amide-like immunoreactivity in neuronal elements in the hypothalamus suggested a role for this in the hypothalamic control of the anterior pituitary function. The injection of 200 ng (313.8 pM) of FMRFamide (in 2 uL) produces a significantly increased plasma GH 15 min after injection. The GH-increasing effect of 400-800 ng (627-1255 pM) of FMRFamide is already developed after 5 min and lasted up to 30 min^[3].

References

[1] Kits KS, et al. Phe-Met-Arg-Phe-amide activates a novel voltage-dependent K+ current through a lipoxygenasepathway in molluscan neurones. J Gen Physiol. 1997 Nov;110(5):611-28. DOI:10.1085/jgp.110.5.611
[2] Sorenson RL, et al. Phe-met-arg-phe-amide (FMRF-NH2) inhibits insulin and somatostatin secretion and anti-FMRF-NH2 sera detects pancreatic polypeptide cells in the rat islet. Peptides. 1984 Jul-Aug;5(4):777-82. DOI:10.1016/0196-9781(84)90021-4
[3] Ottlecz A, et al. Phe-Met-Arg-Phe-amide (FMRFamide) stimulated growth hormone secretion in conscious OVX rats. Neuropeptides. 1987 Feb-Mar;9(2):161-7. DOI:10.1016/0143-4179(87)90054-0

FMRF AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

FMRF AMIDE Suppliers

Global( 86)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
Moxin Chemicals	+8617320513646	Anna@molcoo.com	China	9882	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42953	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4861	58

Supplier	Advantage
Hangzhou Go Top Peptide Biotech	58
Chengdu Youngshe Chemical Co., Ltd.	58
Nanjing TGpeptide	58
Changsha MOL Changes Biotechnology Co., Ltd.	58
Moxin Chemicals	58
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
BOC Sciences	65
MedChemexpress LLC	58

152165-14-5(FMRF AMIDE)Related Search:

FMRF-AMIDE LIKE PEPTIDE 1 (LOBSTER),FMRF AMIDE-LIKE PEPTIDE I, LOBSTER FMRF amide (Nle-Arg-Phe-NH2) FMRF amide (Phe-Met-Arg-Phe) FMRF amide-like Peptide II (lobster) (Thr-Asn-Arg-Asn-Phe-Leu-Arg-Phe-NH2) FMRF amide (Tyr-Phe-Met-Arg-Phe-NH2)

FMRF amide (Ac-Phe-Nle-Arg-Phe-NH2) FMRF amide (Phe-Met-Arg-Phe-NH2) (Molluscan Cardioexcitatory Neuropeptide) FMRF amide (AF-2) (Lys-His-Glu-Tyr-Leu-Arg-Phe-NH2) FMRF amide (AF-1) (Lys-Asn-Glu-Phe-Ile-Arg-Phe-NH2) FMRF amide (Phe-Leu-Arg-Arg)

H-TYR-PHE-MET-ARG-PHE-NH2 [D-MET2]-FMRF-AMIDE FMRF amide (Trp-Nle-Arg-Phe-NH2) FMRF amide (Met-Arg-Phe) H-TYR-GLY-GLY-PHE-MET-ARG-PHE-NH2

TYR-MET-ARG-PHE-NH2 FMRF AMIDE FMRF amide [D-Phe4] (Phe-Met-Arg-D-Phe-NH2)

1of4

PHE-MET-ARG-PHE AMIDE PHE-MET-ARG-PHE-NH2 PHE-MET-ARG-PHE-NH2 1/2ACOH 2H2O MOLLUSCAN CARDIOEXCITATORY PEPTIDE MOLLUSCAN CARDIOEXCITATORY NEUROPEPTIDE MOLLUSCAN CARDIOEXCITATORY NEUROPEPTIDE 1 1/2 ACOH 2H2O MOLLUSCAN CARDIOEXCITATORY NEUROPEPTIDE ACETATE SALT H-PHE-MET-ARG-PHE-NH2 H-PHE-MET-ARG-PHE-NH2 ACETATE SALT H-PHE-MET-ARG-PHE-NH2 ACOH FMRF-NH2 FMRF AMIDE MOLLUSCAN CARDIOEXCITATORY PEPTIDE FMRF AMIDE FMRF-AMIDE 1 1/2ACOH 2H2O FMRFAMIDE ACETATE SALT PHE-MET-ARG-PHE-NH2: FMRF-NH2 H-Phe-Met-Arg-Phe-NH2 acetate 152165-14-5 C31H46N8O6S Invertebrate Neuropeptides Other Neuropeptides Peptides BioChemical Amino Acids and Peptides Biochemicals and Reagents Peptide