3-(Dimethylamino)benzonitrile
- CAS No.
- 38803-30-4
- Chemical Name:
- 3-(Dimethylamino)benzonitrile
- Synonyms
- 3-(Dimethylamino)benzonitrile;Benzonitrile, 3-(dimethylamino)-;3-[DI(METHYL-D3)AMINO]BENZONITRILE
- CBNumber:
- CB82367792
- Molecular Formula:
- C9H10N2
- Molecular Weight:
- 146.19
- MDL Number:
- MFCD00159008
- MOL File:
- 38803-30-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 |
| HS Code | 2922390090 |
3-(Dimethylamino)benzonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR400644 | 3-(Dimethylamino)benzonitrile 97% | 38803-30-4 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR400644 | 3-(Dimethylamino)benzonitrile 97% | 38803-30-4 | 1g | $40 | 2026-06-04 | Buy |
| Apolloscientific | OR400644 | 3-(Dimethylamino)benzonitrile 97% | 38803-30-4 | 5g | $149 | 2026-06-04 | Buy |
| Apolloscientific | OR400644 | 3-(Dimethylamino)benzonitrile 97% | 38803-30-4 | 10g | $274 | 2026-06-04 | Buy |
| Activate Scientific | AS25494 | 3-(Dimethylamino)benzonitrile 95% | 38803-30-4 | 250mg | $96 | 2026-06-04 | Buy |
3-(Dimethylamino)benzonitrile Chemical Properties, Uses, Production
Synthesis
50-00-0
2237-30-1
38803-30-4
To a solution of m-aminobenzonitrile (1.0 g, 8.5 mmol) and formaldehyde (2.1 g, 69.0 mmol) in acetonitrile (20 mL) was added sodium cyanoborohydride (2.7 g, 42.5 mmol). The reaction mixture was stirred at room temperature for 2 hours. Acetic acid (100 mL) was added to adjust the pH to 7 and stirring was continued for 2 hours. Potassium hydroxide solution (1N, 100 mL) was then added and the mixture was extracted with ethyl acetate (100 mL x 2). The organic layers were combined, washed with saturated saline (80 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with petroleum ether/ethyl acetate (10:1) as eluent to give 3-(dimethylamino)benzonitrile (1.3 g, 100%) as a colorless oil. Mass spectrum (MS): m/z 147.3 ([M+H]+).
References
[1] Patent: WO2018/132372, 2018, A1. Location in patent: Paragraph 00470
[2] Bioorganic and Medicinal Chemistry Letters, 1996, vol. 6, # 5, p. 565 - 568
[3] European Journal of Medicinal Chemistry, 1998, vol. 33, # 5, p. 363 - 374
[4] Journal of Chemical Physics, 1988, vol. 88, # 2, p. 871 - 878
3-(Dimethylamino)benzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Accela ChemBio Inc. | +1(858) 699-3322 | marketing@accelachem.com | United States | 6022 | 65 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Suzhou Nuoouman Biological Technology Co., Ltd. | 15026866316 | 180642609@qq.com | China | 4966 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 400821072 | malulu@leyan.com | China | 24933 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Shanghai Vigor Biotechnology Co., Ltd. | 021-18017654 18017654809 | sales@vigorchem.cn | China | 958 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26012 | 58 |
