4-N-BOC-AMINO-CYCLOHEXANOL
- CAS No.
- 224309-64-2
- Chemical Name:
- 4-N-BOC-AMINO-CYCLOHEXANOL
- Synonyms
- 4-(Boc-amino)cyclohexanol;tert-butyl cyclohexylcarbaMate;N-4-Boc-aminocyclohexanol;4-N-BOC-AMINO-CYCLOHEXANOL;N-Boc-4-amino-cyclohexanol;tert-Butyl 4-hydroxycyclohexylcarbaMate;4-(tert-Butoxycarbonylamino)cyclohexanol;4-(tert-Butoxycarbonylamino)cyclohexanol >4-(tert-Butoxycarbonylamino)cyclohexanol;1,1-Dimethylethyl N-(4-hydroxycyclohexyl)carbamate
- CBNumber:
- CB8243810
- Molecular Formula:
- C11H21NO3
- Molecular Weight:
- 215.29
- MDL Number:
- MFCD06658349
- MOL File:
- 224309-64-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| tert-Butyl N-(4-hydroxycyclohexyl)carbamate AldrichCPR | ANV00037 | 1 g | $191 |
| 4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N) | B4714 | 1g | $26 |
| 4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N) | B4714 | 5g | $81 |
| 4-(tert-Butoxycarbonylamino)cyclohexanol | 154011 | 1.00g | $139 |
| tert-Butyl (4-hydroxycyclohexyl)carbamate 97% | B55100 | 1g | $30 |
| More product size | |||
| Melting point | 170.0 to 174.0 °C |
|---|---|
| Boiling point | 337.7±31.0 °C(Predicted) |
| Density | 1.06±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Dichloromethane, DMSO, Methanol |
| form | Solid |
| pka | 12.36±0.40(Predicted) |
| color | White |
| InChI | InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-8-4-6-9(13)7-5-8/h8-9,13H,4-7H2,1-3H3,(H,12,14) |
| InChIKey | DQARDWKWPIRJEH-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NC1CCC(O)CC1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50 |
| Safety Statements | 61 |
| WGK Germany | WGK 3 |
| HS Code | 2924.29.9500 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 |
4-N-BOC-AMINO-CYCLOHEXANOL price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | ANV00037 | tert-Butyl N-(4-hydroxycyclohexyl)carbamate AldrichCPR | 224309-64-2 | 1 g | $191 | 2026-04-30 | Buy |
| TCI Chemical | B4714 | 4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N) | 224309-64-2 | 1g | $26 | 2026-04-30 | Buy |
| TCI Chemical | B4714 | 4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N) | 224309-64-2 | 5g | $81 | 2026-04-30 | Buy |
| Matrix Scientific | 154011 | 4-(tert-Butoxycarbonylamino)cyclohexanol | 224309-64-2 | 1.00g | $139 | 2026-05-18 | Buy |
| Synthonix | B55100 | tert-Butyl (4-hydroxycyclohexyl)carbamate 97% | 224309-64-2 | 1g | $30 | 2026-05-06 | Buy |
4-N-BOC-AMINO-CYCLOHEXANOL Chemical Properties,Uses,Production
Chemical Properties
White Solid
Synthesis Reference(s)
Chemistry Letters, 22, p. 1273, 1993
Tetrahedron Letters, 33, p. 2677, 1992 DOI: 10.1016/S0040-4039(00)79055-1
Synthesis
24424-99-5
6850-65-3
224309-64-2
General procedure: di-tert-butyl dicarbonate (4.087 mL, 21.01 mmol) and diisopropylethylamine (2.87 mL, 17.4 mmol) were dissolved in anhydrous THF (60 mL) under nitrogen protection. Subsequently, (1R,4R)-4-aminocyclohexanol (2.00 g, 17.4 mmol) was slowly added to this solution. The reaction mixture was stirred at room temperature (25°C) for 4 h. The progress of the reaction was monitored by TLC. After completion of the reaction, the mixture was concentrated to dryness in a rotary evaporator. The residue was dried overnight under high vacuum to afford 4-(Boc-amino)cyclohexanol as a white solid (3.49 g, 87.0% yield). The product could be used in subsequent reactions without further purification.
References
[1] Patent: WO2017/100662, 2017, A1. Location in patent: Page/Page column 103; 123
[2] Patent: WO2013/107405, 2013, A1. Location in patent: Page/Page column 48-49
[3] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 2017 - 2021
[4] Patent: US5516806, 1996, A
[5] Patent: WO2013/107291, 2013, A1. Location in patent: Page/Page column 63; 64
4-N-BOC-AMINO-CYCLOHEXANOL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9542 | 58 |
View Lastest Price from 4-N-BOC-AMINO-CYCLOHEXANOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-12-26 | 4-N-BOC-AMINO-CYCLOHEXANOL
224309-64-2
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
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- 4-N-BOC-AMINO-CYCLOHEXANOL
224309-64-2
- $1.00
- 99%
- Career Henan Chemical Co
