4-bromo-3-bromomethyl-benzoic acid methyl ester
- CAS No.
- 142031-67-2
- Chemical Name:
- 4-bromo-3-bromomethyl-benzoic acid methyl ester
- Synonyms
- Methyl 4-broMo-3-(broMoMethyl)benzoate;3-bromo-methyl-4-bromo-benzoate;3-bromethyl-4-bromethyl benzoate;Methyl 3-(bromomethyl)-3-bromophenylacetate;3-Bromomethyl-4-bromobenzoic acid methyl ester;4-BROMO-3-BROMOMETHYL-BENZOIC ACID METHYL ESTER;Benzoic acid, 4-bromo-3-(bromomethyl)-, methyl ester
- CBNumber:
- CB82465883
- Molecular Formula:
- C9H8Br2O2
- Molecular Weight:
- 307.97
- MDL Number:
- MFCD11858300
- MOL File:
- 142031-67-2.mol
- MSDS File:
- SDS
| Boiling point | 356.9±32.0 °C(Predicted) |
|---|---|
| Density | 1.780±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | White flakes |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C9H8Br2O2/c1-13-9(12)6-2-3-8(11)7(4-6)5-10/h2-4H,5H2,1H3 |
| InChIKey | GRJDNFSKEWOMIM-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=C(Br)C(CBr)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P301+P310 |
| HS Code | 2916399090 |
4-bromo-3-bromomethyl-benzoic acid methyl ester price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | SFA03167 | Methyl 4-bromo-3-(bromomethyl)benzoate | 142031-67-2 | 2g | $250 | 2026-06-05 | Buy |
| Biosynth | SFA03167 | Methyl 4-bromo-3-(bromomethyl)benzoate | 142031-67-2 | 5g | $472 | 2026-06-05 | Buy |
| Biosynth | SFA03167 | Methyl 4-bromo-3-(bromomethyl)benzoate | 142031-67-2 | 10g | $767 | 2026-06-05 | Buy |
| Biosynth | SFA03167 | Methyl 4-bromo-3-(bromomethyl)benzoate | 142031-67-2 | 25g | $1298 | 2026-06-05 | Buy |
| Apolloscientific | OR400600 | Methyl 4-Bromo-3-(bromomethyl)benzoate 96% | 142031-67-2 | 250mg | $49 | 2026-06-04 | Buy |
4-bromo-3-bromomethyl-benzoic acid methyl ester Chemical Properties, Uses, Production
Synthesis
In a 6-liter reactor equipped with a condenser, a central mechanical stirrer, and a thermometer, introduce 575 g (2.5 mol) of methyl 4-bromo-3-methylbenzoate, 3 liters of methylene chloride, 494 g (2.75 mol) of N-bromosuccinimide and 17 g of benzoyl peroxide (0.05 mol; 70percent in water). Heat the mixture at reflux under irradiation with a 1000-watt lamp for 10 h. Wash the mixture twice with 1 liter of water, then with 1 liter of saturated sodium chloride solution. Evaporate the methylene chloride. Recrystallize the crude product obtained from heptane. This gives 596 g of 4-bromo-3-bromomethyl-benzoic acid methyl ester as off-white crystals.
References
[1] Patent: US2007/15931, 2007, A1. Location in patent: Page/Page column 6
[2] Patent: US2010/4159, 2010, A1. Location in patent: Page/Page column 59; 62
[3] Patent: WO2006/110173, 2006, A2. Location in patent: Page/Page column 78-79
[4] Chemische Berichte, 1993, vol. 126, # 7, p. 1635 - 1642
[5] ChemMedChem, 2015, vol. 10, # 4, p. 688 - 714
4-bromo-3-bromomethyl-benzoic acid methyl ester Preparation Products And Raw materials
4-bromo-3-bromomethyl-benzoic acid methyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Sheepchem Co., Ltd. | +86 (21) 6715-7650 | sheepchem@163.com | China | 993 | 60 |
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| Shanghai Leto Pharmatech Co.,Ltd. | 86-021-5821 5861; 18016401466 | sales@letopharm.com | China | 235 | 58 |
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| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 | sales@shiyabiopharm.com | China | 9814 | 58 |
| Shanghai Brain Biotechnology Co., Ltd. | 13564638271 | shhjiang1977@163.com | China | 2983 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
