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4-(Methylthio)phenol

4-(Methylthio)phenol structure

CAS No.: 1073-72-9

Chemical Name:: 4-(Methylthio)phenol

Synonyms: Phenol, 4-(methylthio)-;FEXI-003;4-Methtyl phenol;MethylMercapto)pheno;4-(methylthio)-pheno;4-(Methylthio)phenol;4-Hydroxythioanisole;p-(methylthio)-pheno;p-Hydroxythioanisole;Of (Methylthio) phenol

CBNumber:: CB8248219

Molecular Formula:: C7H8OS

Molecular Weight:: 140.2

MDL Number:: MFCD08443600

MOL File:: 1073-72-9.mol

MSDS File:: SDS

Last updated:2026-06-04 16:00:12

Product description	Number	Pack Size	Price
4-(Methylmercapto)phenol 98%	550426	25g	$76.5
4-(Methylthio)phenol >98.0%(GC)(T)	M0441	25g	$116
4-(Methylthio)phenol >98.0%(GC)(T)	M0441	250g	$864
4-(Methylmercapto)phenol	TRC-M320160-25G	25g	$135
4-(Methylmercapto)phenol	TRC-M320160-1G	1g	$64
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4-(Methylthio)phenol Properties

Melting point	84-86 (lit.)
Boiling point	153-156 °C/20 mmHg (lit.)
Density	1.1182 (rough estimate)
refractive index	1.5530 (estimate)
Flash point	153-156°C/20mm
storage temp.	Inert atmosphere,Room Temperature
solubility	soluble in Chloroform, Methanol
form	Powder or Crystalline Powder
pka	9.53(at 25℃)
color	White to pale brown
Water Solubility	Soluble in water 9.59 g/ l.
InChI	1S/C7H8OS/c1-9-7-4-2-6(8)3-5-7/h2-5,8H,1H3
InChIKey	QASBCTGZKABPKX-UHFFFAOYSA-N
SMILES	CSc1ccc(O)cc1
LogP	1.780
CAS DataBase Reference	1073-72-9(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	9T83QI0Z1L
NIST Chemistry Reference	Phenol, 4-(methylthio)-(1073-72-9)
EPA Substance Registry System	Phenol, 4-(methylthio)- (1073-72-9)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H319-H412-H315-H335

Precautionary statements

P280a-P304+P340-P305+P351+P338-P405-P501a-P261-P264-P270-P271-P273-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37

RIDADR

UN 3335

WGK Germany

RTECS

SM1578500

TSCA

TSCA listed

HazardClass

STENCH

HS Code

29309090

Storage Class

11 - Combustible Solids

Limited Quantities

5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
2		0

4-(Methylthio)phenol price More Price(53)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	550426	4-(Methylmercapto)phenol 98%	1073-72-9	25g	$76.5	2026-04-30	Buy
TCI Chemical	M0441	4-(Methylthio)phenol >98.0%(GC)(T)	1073-72-9	25g	$116	2026-04-30	Buy
TCI Chemical	M0441	4-(Methylthio)phenol >98.0%(GC)(T)	1073-72-9	250g	$864	2026-04-30	Buy
TRC	TRC-M320160-25G	4-(Methylmercapto)phenol	1073-72-9	25g	$135	2026-06-03	Buy
TRC	TRC-M320160-1G	4-(Methylmercapto)phenol	1073-72-9	1g	$64	2026-06-03	Buy

Product number	Packaging	Price	Buy
550426	25g	$76.5	Buy
M0441	25g	$116	Buy
M0441	250g	$864	Buy
TRC-M320160-25G	25g	$135	Buy
TRC-M320160-1G	1g	$64	Buy

4-(Methylthio)phenol Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

4-(Methylmercapto)phenol [4-(Methylthio)phenol] may be used in the preparation of phosphoramidodithioate intermediates for the synthesis of sulprofos amidate.

Definition

ChEBI: 4-(methylsulfanyl)phenol is an aryl sulfide and a member of phenols.

General Description

4-(Methylmercapto)phenol (4MP) mediates the removal of benzyloxycarbonyl and O-benzyl protecting groups by accepting the benzyl groups during the acidolytic cleavage with trifluoroacetic acid. The presence of hydroxyl group in the para position enhances the rate of hydrodesulfurization (HDS) of 4MP.

Synthesis

4-Methylthiobenzeneboronic acid (0.3 mmol,1.0equiv) was added to a dried 20 mL quartz test tube and the quartz test tube was evacuated while backfilled with oxygen three times. Under oxygen conditions, Et3N (62.5 L,0.45 mmol,1.5equiv) and 2-methyltetrahydrofuran (4 ml) were added sequentially via syringe. The resulting mixture was stirred for 5 min and then the quartz test tube was transferred to a photoreactor. The test tube was placed about 2 cm from a 15 W UV lamp. The reaction mixture was stirred and photoreacted for 24 h. After the indicated time, the crude product was diluted with ethyl acetate, filtered through a pad of silica gel and concentrated under reduced pressure. The desired product was then obtained by direct silica gel rapid chromatography using silica gel (EtOAc/PE = 1/10).

4-(Methylthio)phenol Preparation Products And Raw materials

Raw materials

Dimethyl disulfide

Preparation Products

4-(Methylsulfonyl)phenol S-METHYL-S-(4-HYDROXYPHENYL) SULFOXIMINE 4-(METHYLSULFINYL)PHENOL SULPROFOS 4-Hydroxyphenylboronic acid pinacol ester

4-(METHANESULFINYL)BENZENEBORONIC ACID 2-hydroxy-5-(methylthio)benzaldehyde 4,4′-dihydroxydiphenyl disulfide 2-HYDROXYTHIOANISOLE C.I. Disperse Red 132

3-[4-(Methylthio)phenoxy]propionic Acid (p-hydroxyphenyl)dimethylsulphonium chloride

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4-(Methylthio)phenol Suppliers

Global( 276)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Shaanxi Dideu Medichem Co. Ltd	+8617392709771	1097@dideu.com	China	3992	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60
career henan chemical co	58
Shandong chuangyingchemical Co., Ltd.	58
Wuhan Chemwish Technology Co., Ltd	58

View Lastest Price from 4-(Methylthio)phenol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	4-(Methylthio)phenol 1073-72-9	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-12-24	4-(Methylthio)phenol 1073-72-9		1KG	98.0%	10	Shaanxi Dideu Medichem Co. Ltd
2025-09-25	4-(Methylthio)phenol 1073-72-9	$2.00-5.00	1kg	99%		Henan Fengda Chemical Co., Ltd

4-(Methylthio)phenol
1073-72-9
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-(Methylthio)phenol
1073-72-9
$0.10
98.0%
Shaanxi Dideu Medichem Co. Ltd

4-(Methylthio)phenol
1073-72-9
$2.00-5.00
99%
Henan Fengda Chemical Co., Ltd

4-(Methylthio)phenol Spectrum

4-(Methylthio)phenol(1073-72-9)MS 4-(Methylthio)phenol(1073-72-9)¹HNMR 4-(Methylthio)phenol(1073-72-9)¹³CNMR 4-(Methylthio)phenol(1073-72-9)IR1 4-(Methylthio)phenol(1073-72-9)IR2 4-(Methylthio)phenol(1073-72-9)IR3

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4-(Methylmercapto)phenol 98% 4-(Methylsulfanyl)phenol 4-(methylthio)-pheno 4-Hydroxyphenyl methyl sulfide MethylMercapto)pheno Methyl 4-hydroxyphenyl sulfide FEXI-003 3-ACETAMIDE THIOANISOLE 4-(Methylmercapto)phenol,tech. 4-(METHYLTHIO)PHENOL,97% 4-(METHYLTHIO)PHENOL 98+% 4-(Methylmercapto)phenol 4-(Methylthio)phenol 4-Hydroxythioanisole p-(methylthio)-pheno Phenol, p-(methylthio)- p-Hydroxyphenyl methyl sulfide p-Hydroxythioanisole Of (Methylthio) phenol 4-Hydroxythioanisole, 4-(Methylsulphanyl)phenol, 4-(Methylmercapto)phenol 4-(Methylsulphanyl)phenol 4-(Methylthio)phenol> 4-(Methylmercapto)phenol, 97%, 4-Methtyl phenol Phenol, 4-(methylthio)- 1073-72-9 1077-72-9 CH3SC6H4OH Organic Building Blocks Sulfur Compounds Thiols/Mercaptans Building Blocks Protection & Derivatization Reagents (for Synthesis) Synthetic Organic Chemistry Phenoles and thiophenoles 1073-72-9