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5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine structure

CAS No.: 1111638-02-8

Chemical Name:: 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine

Synonyms: 2-Methyl-5-bromo-7-azaindole;5-Bromo-2-methyl-7-Azaind...;5-Bromo-2-methyl-7-Azaindole;5-Bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine;5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2-Methyl-

CBNumber:: CB82489968

Molecular Formula:: C8H7BrN2

Molecular Weight:: 211.06

MDL Number:: MFCD15529124

MOL File:: 1111638-02-8.mol

Last updated:2025-07-24 18:13:41

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5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Properties

Density	1.654
storage temp.	Sealed in dry,Room Temperature
pka	13.49±0.40(Predicted)
form	powder
color	Yellow
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H412
Precautionary statements	P280
Hazard Codes	Xn
Risk Statements	22-41
WGK Germany	3
HazardClass	IRRITANT
HS Code	2933998090

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE001093	5-Bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine Aldrich^CPR		1 g	$1030	2025-07-31	Buy
Sigma-Aldrich	ADE001092	5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Aldrich	1111638-02-8	1g	$1030	2025-07-31	Buy
TRC	B697663	5-Bromo-2-methyl-1h-pyrrolo[2,3-b]pyridine	1111638-02-8	50mg	$65	2021-12-16	Buy
Matrix Scientific	059416	5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine	1111638-02-8	250mg	$115	2021-12-16	Buy
Matrix Scientific	059416	5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine	1111638-02-8	500mg	$205	2021-12-16	Buy

Product number	Packaging	Price	Buy
ADE001093	1 g	$1030	Buy
ADE001092	1g	$1030	Buy
B697663	50mg	$65	Buy
059416	250mg	$115	Buy
059416	500mg	$205	Buy

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Chemical Properties,Uses,Production

Synthesis

5-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

1111638-01-7

1111638-02-8

Preparation of Method A Steps for the synthesis of intermediate 4: 5-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine: Ingredient 3 (88 mg, 0.251 mmol) was dissolved in methanol (4 mL), 2 N sodium hydroxide solution (1 mL) was added, and the reaction mixture was heated and refluxed for 2 hours. After completion of the reaction, ethyl acetate was added for extraction and the organic phase was washed sequentially with 1 N sodium hydroxide solution and water. Purification by silica gel column chromatography (slow gradient elution, volume fraction of methanol in dichloromethane increased from 0% to 2%) afforded the target product 4 (40 mg, 0.19 mmol, 76% yield). Product characterization data were as follows: 1H NMR (CDCl3, 300 MHz): δ 10.26 (br s, 1H), 8.22 (d, J = 2.1 Hz, 1H), 8.92 (d, J = 2.1 Hz, 1H), 6.13 (s, 1H), 2.52 (s, 3H). MS (m/z): 210 (M + H).

References

[1] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 5, p. 582 - 586
[2] Patent: WO2011/149950, 2011, A2. Location in patent: Page/Page column 151-152
[3] Patent: WO2014/85795, 2014, A1. Location in patent: Paragraph 0394
[4] Bioorganic Chemistry, 2016, vol. 65, p. 146 - 158
[5] Patent: WO2009/16460, 2009, A2. Location in patent: Page/Page column 74

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine synthesis

Synthesis of 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine from 2-PyridinaMine, 5-broMo-3-(1-propyn-1-yl)-

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Preparation Products And Raw materials

Raw materials

2-PyridinaMine, 5-broMo-3-(1-propyn-1-yl)- 2-AMINO-5-BROMO-3-IODOPYRIDINE 5-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine 5-Bromo-7-azaindole 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-(phenylsulfonyl)-

2-Amino-5-bromopyridine Sodium hydroxide Methanol

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Preparation Products

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Suppliers

Global( 103)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29731	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49733	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29804	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; +8619817745290	bd@blocksynth.com	China	5661	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49983	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
LEAPCHEM CO., LTD.	58

View Lastest Price from 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-09	5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine 1111638-02-8	US $9.80 / KG	1g	≥99%	100kg	Career Henan Chemical Co

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine
1111638-02-8
US $9.80 / KG
≥99%
Career Henan Chemical Co

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Spectrum

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine(1111638-02-8)¹HNMR

1111638-02-8(5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine)Related Search:

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5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine 5-Bromo-2-methyl-7-Azaindole 5-Bromo-2-methyl-7-Azaind... 5-Bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2-Methyl- 2-Methyl-5-bromo-7-azaindole 1111638-02-8 Azaindoles