6-Chloro-5-nitropyridine-2-carboxylic acid
- CAS No.
- 353277-27-7
- Chemical Name:
- 6-Chloro-5-nitropyridine-2-carboxylic acid
- Synonyms
- 6-chloro-5-nitropicolinic acid;6-Chloro-5-nitropyridine-2-carboxylic acid;2-Pyridinecarboxylic acid, 6-chloro-5-nitro-;Benzo[b]thiophene-2-carboxylicacid,5,7-dimethoxy-,methylester
- CBNumber:
- CB82506689
- Molecular Formula:
- C6H3ClN2O4
- Molecular Weight:
- 202.55
- MDL Number:
- MFCD01927937
- MOL File:
- 353277-27-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Chloro-5-nitropicolinic acid 98% | C41846 | 100mg | $17 |
| 6-Chloro-5-nitropicolinic acid 98% | C41846 | 250mg | $22 |
| 6-Chloro-5-nitropicolinic acid 98% | C41846 | 1g | $40 |
| 6-Chloro-5-nitropicolinic acid 98% | C41846 | 5g | $110 |
| 6-Chloro-5-nitro-pyridine-2-carboxylic acid ＞97% | BB20-3243 | 5G | $85 |
| Boiling point | 413.6±45.0 °C(Predicted) |
|---|---|
| Density | 1.702±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 2.34±0.13(Predicted) |
| Appearance | Off-white to light green Solid |
| InChI | InChI=1S/C6H3ClN2O4/c7-5-4(9(12)13)2-1-3(8-5)6(10)11/h1-2H,(H,10,11) |
| InChIKey | WMPMXUCWDZXMEW-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=NC(Cl)=C([N+]([O-])=O)C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
6-Chloro-5-nitropyridine-2-carboxylic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | C41846 | 6-Chloro-5-nitropicolinic acid 98% | 353277-27-7 | 100mg | $17 | 2026-05-06 | Buy |
| Synthonix | C41846 | 6-Chloro-5-nitropicolinic acid 98% | 353277-27-7 | 250mg | $22 | 2026-05-06 | Buy |
| Synthonix | C41846 | 6-Chloro-5-nitropicolinic acid 98% | 353277-27-7 | 1g | $40 | 2026-05-06 | Buy |
| Synthonix | C41846 | 6-Chloro-5-nitropicolinic acid 98% | 353277-27-7 | 5g | $110 | 2026-05-06 | Buy |
| Chemcia Scientific | BB20-3243 | 6-Chloro-5-nitro-pyridine-2-carboxylic acid ＞97% | 353277-27-7 | 5G | $85 | 2026-05-24 | Buy |
6-Chloro-5-nitropyridine-2-carboxylic acid Chemical Properties,Uses,Production
Synthesis
56057-19-3
353277-27-7
General procedure for the synthesis of 6-chloro-5-nitro-2-pyridinecarboxylic acid from 6-chloro-5-nitro-2-methylpyridine: 6-chloro-5-nitro-2-methylpyridine (97 g, 560 mmol) was slowly added to a reaction flask pre-filled with 18 M sulfuric acid (400 mL) under stirring conditions. Subsequently, chromium trioxide (169 g, 1.69 mol) was added to the reaction mixture in small portions and the reaction temperature was controlled to be below 50 °C. The reaction mixture was stirred continuously at 15 °C for 20 hours. Upon completion of the reaction, the mixture was quenched by pouring it into 2 Kg of ice water and the resulting solid product was collected by filtration. The resulting solid was dried under vacuum to give 6-chloro-5-nitro-2-pyridinecarboxylic acid (103 g, 90% yield) as a pale white solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) with chemical shifts of δ 8.70 (d, 1H), 8.24 (d, 1H).
References
[1] Patent: US2018/170908, 2018, A1. Location in patent: Paragraph 0429
[2] Patent: EP2366691, 2011, A1. Location in patent: Page/Page column 12
[3] Patent: WO2016/176460, 2016, A1. Location in patent: Page/Page column 114; 158
6-Chloro-5-nitropyridine-2-carboxylic acid Preparation Products And Raw materials
6-Chloro-5-nitropyridine-2-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| ShanghaiFineBiotechCoLtd | +8618717800556 18717800556 | sales@finebioetch.com | CHINA | 318 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 | sales@tihondan.com | China | 3767 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
View Lastest Price from 6-Chloro-5-nitropyridine-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 6-Chloro-5-nitropyridine-2-carboxylic acid
353277-27-7
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 6-Chloro-5-nitropyridine-2-carboxylic acid
353277-27-7
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
