4-methyl-7-nitro-1H-indole-3-carbaldehyde
- CAS No.
- 289483-81-4
- Chemical Name:
- 4-methyl-7-nitro-1H-indole-3-carbaldehyde
- Synonyms
- 4-Methyl-7-nitro-1H-indole-3-caCSAldehyde;4-methyl-7-nitro-1H-indole-3-carbaldehyde;4-methyl-7-nitro-1H-Indole-3-carboxaldehyde;1H-Indole-3-carboxaldehyde, 4-methyl-7-nitro-
- CBNumber:
- CB82514976
- Molecular Formula:
- C10H8N2O3
- Molecular Weight:
- 204.18
- MDL Number:
- MFCD17779299
- MOL File:
- 289483-81-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4-methyl-7-nitro-1H-indole-3-carbaldehyde price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA002X2S | 4-Methyl-7-nitro-1H-indole-3-carboxaldehyde 97% | 289483-81-4 | 100mg | $377 | 2026-05-28 | Buy |
| aablocks | AA002X2S | 4-Methyl-7-nitro-1H-indole-3-carboxaldehyde 97% | 289483-81-4 | 250mg | $569 | 2026-05-28 | Buy |
| aablocks | AA002X2S | 4-Methyl-7-nitro-1H-indole-3-carboxaldehyde 97% | 289483-81-4 | 1g | $1107 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD280144 | 4-Methyl-7-nitro-1H-indole-3-carbaldehyde 95% | 289483-81-4 | 100MG | $375 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD280144 | 4-Methyl-7-nitro-1H-indole-3-carbaldehyde 95% | 289483-81-4 | 250MG | $585 | 2026-05-27 | Buy |
4-methyl-7-nitro-1H-indole-3-carbaldehyde Chemical Properties, Uses, Production
Synthesis
289483-80-3
68-12-2
289483-81-4
To 12 mL (154 mmol) of N,N-dimethylformamide was slowly added 1.5 mL (16.1 mmol) of phosphoryl chloride at 0 °C, kept at 0 °C and stirred for 20.5 hours. Subsequently, 2.0 g (11.4 mmol) of 4-methyl-7-nitro-1H-indole dissolved in 20 mL of N,N-dimethylformamide was added dropwise to the reaction mixture at the same temperature. The reaction system was warmed up to 90 °C with continuous stirring for 21 hours. Upon completion of the reaction, the reaction mixture was cooled to 0 °C and the reaction was quenched by the addition of 100 mL of aqueous 1N sodium hydroxide solution. The reaction mixture was extracted with ethyl acetate, the organic phase was washed sequentially with water and saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent. A mixed solvent of tert-butyl methyl ether and hexane was added to the residue, a solid was precipitated, and the crystals were collected by filtration to give 2.23 g of 4-methyl-7-nitro-1H-indole-3-carbaldehyde in 95.8% yield. The product was characterized by 1H-NMR (DMSO-d6): δ 2.90 (3H, s), 7.21 (1H, d, J = 8.4 Hz), 8.11 (1H, d, J = 8.4 Hz), 8.39 (1H, s), 10.01 (1H, s), 12.71 (1H, br s).
References
[1] Patent: US2007/37854, 2007, A1. Location in patent: Page/Page column 5
4-methyl-7-nitro-1H-indole-3-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
4-methyl-7-nitro-1H-indole-3-carbaldehyde Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Cuisen Pharmaceutical Technology Co., Ltd. | 13472757003 | yongnan.wang@cendrix.cn | China | 974 | 65 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29089 | 58 |
| Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd | 0371-88900765 18037465274 | 3430974218@qq.com | China | 14171 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26012 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20027 | 58 |
| Shanghai Yaocheng Pharmaceutical Technology Partnership (Limited Partnership) | 400-6181121 18616381138 | runran.li@townyuan.com | China | 4367 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
