A 1120
- CAS No.
- 1152782-19-8
- Chemical Name:
- A 1120
- Synonyms
- A 1120;A 1120, 10 mM in DMSO;A-1120,Inhibitor,inhibit,A 1120,A1120;2-(4-(2-(trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid;2-({4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl}amino)benzoic acid;Benzoic acid, 2-[[[4-[2-(trifluoromethyl)phenyl]-1-piperidinyl]carbonyl]amino]-
- CBNumber:
- CB82535656
- Molecular Formula:
- C20H19F3N2O3
- Molecular Weight:
- 392.37
- MDL Number:
- MFCD12912393
- MOL File:
- 1152782-19-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| A1120 ≥98% (HPLC), powder | A3111 | 5mg | $106 |
| A1120 ≥98% (HPLC), powder | A3111 | 25mg | $528 |
| A-1120 ≥95% | 30921 | 5mg | $134 |
| A-1120 ≥95% | 30921 | 10mg | $240 |
| A 1120 | B7498 | 5mg | $436 |
| Boiling point | 572.3±50.0 °C(Predicted) |
|---|---|
| Density | 1.370±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: 100 mM; Ethanol: 25 mM |
| form | powder |
| pka | 4.03±0.36(Predicted) |
| color | off-white |
| InChI | 1S/C20H19F3N2O3/c21-20(22,23)16-7-3-1-5-14(16)13-9-11-25(12-10-13)19(28)24-17-8-4-2-6-15(17)18(26)27/h1-8,13H,9-12H2,(H,24,28)(H,26,27) |
| InChIKey | MEAQCLPMSVEOQF-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccccc1NC(=O)N2CCC(CC2)c3ccccc3C(F)(F)F |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317-H319-H400 | |||||||||
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-36-43-50/53 | |||||||||
| Safety Statements | 26-36/37-60-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Eye Irrit. 2 Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
A 1120 price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A3111 | A1120 ≥98% (HPLC), powder | 1152782-19-8 | 5mg | $106 | 2026-04-30 | Buy |
| Sigma-Aldrich | A3111 | A1120 ≥98% (HPLC), powder | 1152782-19-8 | 25mg | $528 | 2026-04-30 | Buy |
| Cayman Chemical | 30921 | A-1120 ≥95% | 1152782-19-8 | 5mg | $134 | 2026-04-30 | Buy |
| Cayman Chemical | 30921 | A-1120 ≥95% | 1152782-19-8 | 10mg | $240 | 2026-04-30 | Buy |
| ApexBio Technology | B7498 | A 1120 | 1152782-19-8 | 5mg | $436 | 2026-05-06 | Buy |
A 1120 Chemical Properties,Uses,Production
Uses
A 1120 is a a nonretinoid RBP4 antagonist, which inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.
Biochem/physiol Actions
A1120 is a selective non-retinoid ligand for retinol-binding protein 4 (RBP4). RBP4 transports retinol from the liver to extrahepatic tissues and RBP4 lowering is reported to improve insulin sensitivity in mice. A1120 is a high affinity non-retinoid ligand for RBP4 which disrupts the interaction between RBP4 and its binding partner transthyretin (TTR). It binds to the same site as retinol and induces changes in the orientation (compared to the retinol bound form) of loops at the RBP4-TTR interaction interface.A1120 lowers RBP4 and retinol levels in a dose-dependent manner, to a similar extent as seen with fenretinide. However, unlike fenretinide (Sigma# H7779), A1120 does not have beneficial effects on insulin resistance.
storage
Store at RT
A 1120 Preparation Products And Raw materials
Raw materials
Preparation Products
A 1120 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19957 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29974 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301593;18013301590 | njduly@126.com | China | 3293 | 55 |
View Lastest Price from A 1120 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | A 1120
1152782-19-8
|
US $38.00-147.00 / mg | 99.47% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-22 | A 1120
1152782-19-8
|
US $38.00-147.00 / mg | 99.47% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-07-17 | A 1120
1152782-19-8
|
US $38.00-147.00 / mg | 99.11% | 10g | TargetMol Chemicals Inc. |
