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Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE

CAS No.
114014-15-2
Chemical Name:
Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE
Synonyms
Z-FY(T-BU)-DMK;Z-Phe-Tyr(tBu)-CHN2;Cbz-Phe-Tyr(O-t-Bu)-CHN2;CATHEPSIN L INHIBITOR III;Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE;CBZ-PHE-TYR(O-T-BU)-CHN2;Z-PHE-TYR(TBU)-CHN2
CBNumber:
CB8254517
Molecular Formula:
C31H34N4O5
Molecular Weight:
542.63
MDL Number:
MFCD00672349
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
Cathepsin L Inhibitor III The Cathepsin L Inhibitor III controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. 219427 5MG $217
Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 27877 1mg $42
Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 27877 5mg $153
Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 27877 10mg $283
Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 27877 25mg $653

Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Properties

storage temp. -15°C
solubility Ethyl Acetate: 10 mg/ml
form A crystalline solid
color White to off-white
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  WGK 1
Storage Class 11 - Combustible Solids

Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 219427 Cathepsin L Inhibitor III The Cathepsin L Inhibitor III controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. 5MG $217 2026-04-30 Buy
Cayman Chemical 27877 Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 114014-15-2 1mg $42 2026-04-30 Buy
Cayman Chemical 27877 Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 114014-15-2 5mg $153 2026-04-30 Buy
Cayman Chemical 27877 Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 114014-15-2 10mg $283 2026-04-30 Buy
Cayman Chemical 27877 Z-Phe-Tyr(tBu)-diazomethylketone ≥98% 114014-15-2 25mg $653 2026-04-30 Buy
Product number Packaging Price Buy
219427 5MG $217 Buy
27877 1mg $42 Buy
27877 5mg $153 Buy
27877 10mg $283 Buy
27877 25mg $653 Buy

Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Chemical Properties,Uses,Production

Uses

Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection[1][2].

Biological Activity

Cell permeable: yes', 'Primary Target
Cathepsin L', 'Product does not compete with ATP.', 'Reversible: no

IC 50

cathepsin L

References

[1] Ebert DH, et al. Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells. J Biol Chem. 2002 Jul 5;277(27):24609-17. DOI:10.1074/jbc.M201107200
[2] Perez-Bermejo JA, et al. SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19. Sci Transl Med. 2021 Apr 21;13(590):eabf7872. DOI:10.1126/scitranslmed.abf7872

Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Suppliers

Global( 61)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences
16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Nanjing TGpeptide
+86-13347807150 support@tgpeptide.com China 3279 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD 13816107857 sales@fortunechem-sh.com China 981 58
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 7999 62
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19087 58

View Lastest Price from Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Z-Phe-Tyr(tBu)-diazomethylketone pictures 2026-07-27 Z-Phe-Tyr(tBu)-diazomethylketone
114014-15-2
$137.00-493.00 10g TargetMol Chemicals Inc.
CATHEPSIN L INHIBITOR III Z-FY(T-BU)-DMK Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Cbz-Phe-Tyr(O-t-Bu)-CHN2 CBZ-PHE-TYR(O-T-BU)-CHN2;Z-PHE-TYR(TBU)-CHN2 Z-Phe-Tyr(tBu)-CHN2 114014-15-2