6-cyclopropylpyridin-3-aMine
- CAS No.
- 1159821-66-5
- Chemical Name:
- 6-cyclopropylpyridin-3-aMine
- Synonyms
- 6-Cyclopropyl-3-pyridinamine;6-cyclopropylpyridin-3-aMine;5-Amino-2-cyclopropylpyridine;6-cyclopropylpyridine-3-amine;3-Pyridinamine, 6-cyclopropyl-
- CBNumber:
- CB82563035
- Molecular Formula:
- C8H10N2
- Molecular Weight:
- 134.18
- MDL Number:
- MFCD12033370
- MOL File:
- 1159821-66-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H318-H335 |
| Precautionary statements | P271-P261-P280 |
| HS Code | 2933399990 |
6-cyclopropylpyridin-3-aMine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | JWB82166 | 6-Cyclopropylpyridin-3-amine | 1159821-66-5 | 1g | $295 | 2026-06-04 | Buy |
| Biosynth | JWB82166 | 6-Cyclopropylpyridin-3-amine | 1159821-66-5 | 10g | $2124 | 2026-06-04 | Buy |
| Apolloscientific | OR306607 | 6-Cyclopropylpyridin-3-amine ≥95% | 1159821-66-5 | 250mg | $60 | 2026-06-04 | Buy |
| Activate Scientific | AS43077 | 6-Cyclopropylpyridin-3-amine 95% | 1159821-66-5 | 1g | $158 | 2026-06-04 | Buy |
| Apolloscientific | OR306607 | 6-Cyclopropylpyridin-3-amine ≥95% | 1159821-66-5 | 1g | $181 | 2026-06-04 | Buy |
6-cyclopropylpyridin-3-aMine Chemical Properties, Uses, Production
Synthesis
1190380-55-2
1159821-66-5
2-Cyclopropyl-5-nitropyridine (300 mg, 2.24 mmol) was used as starting material and mixed with 10% palladium/carbon catalyst (32 mg) in ethanol (15 mL). The reaction mixture was stirred overnight at room temperature under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated to obtain the crude product. To improve the conversion, the crude product was reacted again under the same hydrogenation conditions and separated as described previously. Finally, the crude product was purified by preparative HPLC (high pH buffer) to afford the target compound 6-cyclopropylpyridin-3-amine as an orange oil (30 mg, 12% yield). The structure of the product was confirmed by 1H NMR (400 MHz, chloroform-d): δ 0.85-1.06 (m, 4H), 1.98-2.09 (m, 1H), 3.78-4.07 (m, 2H), 6.93 (d, J = 7.79 Hz, 1H), 7.01 (dd, J = 8.24, 2.75 Hz, 1H), 8.06 (d, J = 3.21 Hz, 1H); mass spectrum (ES+APCI+): m/z 135 [M+H]+.
References
[1] Patent: WO2009/122180, 2009, A1. Location in patent: Page/Page column 115
6-cyclopropylpyridin-3-aMine Preparation Products And Raw materials
6-cyclopropylpyridin-3-aMine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9848 | 55 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Combiphos (Shanghai) Biological Technology Co., Ltd. | 021-65232103 17602124823 | combiphos@vip.qq.com | China | 30000 | 58 |
| Chengdu Focus Pharmaceutical Technology Co., Ltd. | 028-64950838 17340131597 | wangmin@focuspharm.com | China | 750 | 58 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22344 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Henan Alfachem Co.,Ltd. | 0371-55051623 18137891487 | 3983243027@qq.com | China | 9974 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
