5-Fluoro-2-Methyl-3-nitrobenzoic acid
- CAS No.
- 850462-64-5
- Chemical Name:
- 5-Fluoro-2-Methyl-3-nitrobenzoic acid
- Synonyms
- 5-Fluoro-3-nitro-o-toluic acid;Benzoic acid, 5-fluoro-2-Methyl-3-nitro-;5-Fluoro-2-Methyl-3-nitrobenzoic acid ISO 9001：2015 REACH
- CBNumber:
- CB82583066
- Molecular Formula:
- C8H6FNO4
- Molecular Weight:
- 199.14
- MDL Number:
- MFCD12913348
- MOL File:
- 850462-64-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-fluoro-2-methyl-3-nitrobenzoicAcid | B441518 | 10mg | $45 |
| Benzoicacid,5-fluoro-2-methyl-3-nitro- 98.81% | CS-M2036 | 5g | $73 |
| Benzoicacid,5-fluoro-2-methyl-3-nitro- 98.81% | CS-M2036 | 25g | $199 |
| 5-Fluoro-2-methyl-3-nitrobenzoicacid | Y5110 | 1g | $205 |
| Benzoicacid,5-fluoro-2-methyl-3-nitro- 98.81% | CS-M2036 | 10g | $107 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H302-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
| HS Code | 2916399090 |
5-Fluoro-2-Methyl-3-nitrobenzoic acid price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B441518 | 5-fluoro-2-methyl-3-nitrobenzoicAcid | 850462-64-5 | 10mg | $45 | 2021-12-16 | Buy |
| ChemScene | CS-M2036 | Benzoicacid,5-fluoro-2-methyl-3-nitro- 98.81% | 850462-64-5 | 5g | $73 | 2021-12-16 | Buy |
| ChemScene | CS-M2036 | Benzoicacid,5-fluoro-2-methyl-3-nitro- 98.81% | 850462-64-5 | 25g | $199 | 2021-12-16 | Buy |
| AK Scientific | Y5110 | 5-Fluoro-2-methyl-3-nitrobenzoicacid | 850462-64-5 | 1g | $205 | 2021-12-16 | Buy |
| ChemScene | CS-M2036 | Benzoicacid,5-fluoro-2-methyl-3-nitro- 98.81% | 850462-64-5 | 10g | $107 | 2021-12-16 | Buy |
5-Fluoro-2-Methyl-3-nitrobenzoic acid Chemical Properties,Uses,Production
Uses
5-Fluoro-2-methyl-3-nitrobenzoic acid can be used in organic synthesis, pharmaceutical intermediates, etc.
Synthesis
33184-16-6
850462-64-5
General procedure for the synthesis of 5-fluoro-2-methyl-3-nitrobenzoic acid (D135) from 2-methyl-5-fluorobenzoic acid: 2-methyl-5-fluorobenzoic acid (20 g) was added in batches to ice-cooled concentrated sulfuric acid (98%, 80 mL), and stirred until all solids were dissolved. A mixture of nitric acid (65%, 6 mL) and concentrated sulfuric acid (98%, 12 mL) was slowly added dropwise at 0°C. The solution was then mixed with a mixture of nitric acid (65%, 6 mL) and concentrated sulfuric acid (98%, 12 mL). After the dropwise addition was completed, the reaction mixture was gradually warmed to room temperature and stirring was continued for 6 hours. Upon completion of the reaction, the mixture was slowly poured into ice (500 g) to quench the reaction and precipitate a solid. The solid was collected by filtration and washed with water (100 mL). The solid was redissolved in ethyl acetate (200 mL) and the organic layer was washed with saturated brine. The organic layer was dried over anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure to give the title compound (11 g) as a brown solid.1H NMR (400 MHz, MeOD-d4): δ 7.84 (dd, J = 8.7, 2.6 Hz, 1H), 7.78 (dd, J = 7.8, 2.8 Hz, 1H), 2.55 (s, 3H).MS (ESI ): m/z calculated value C8H6FNO4 [M-H]- 198, measured value 198.
References
[1] Patent: US2005/131226, 2005, A1. Location in patent: Page/Page column 6-7
[2] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 9, p. 2063 - 2072
[3] Patent: WO2005/35518, 2005, A1. Location in patent: Page/Page column 19
[4] Patent: EP2098513, 2009, A1. Location in patent: Page/Page column 61-62
[5] Patent: WO2005/28445, 2005, A2. Location in patent: Page/Page column 29-30
5-Fluoro-2-Methyl-3-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 340 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
View Lastest Price from 5-Fluoro-2-Methyl-3-nitrobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 5-Fluoro-2-Methyl-3-nitrobenzoic acid
850462-64-5
|
US $1.10 / g | 1g | 99.0% Min | 100 Tons | Dideu Industries Group Limited | |
 |
2019-09-02 | 5-Fluoro-2-Methyl-3-nitrobenzoic acid
850462-64-5
|
US $1.00 / KG | 1KG | 98% | 1kg; 2kg；10kg; 100kg | Career Henan Chemical Co |
-
- 5-Fluoro-2-Methyl-3-nitrobenzoic acid
850462-64-5
- US $1.10 / g
- 99.0% Min
- Dideu Industries Group Limited
-
- 5-Fluoro-2-Methyl-3-nitrobenzoic acid
850462-64-5
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
