15-deoxy-Δ12,14-Prostaglandin J2-biotin
- CAS No.
- Chemical Name:
- 15-deoxy-Δ12,14-Prostaglandin J2-biotin
- Synonyms
- 15-deoxy-Δ12,14-Prostaglandin J2-biotin
- CBNumber:
- CB82589907
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
15-deoxy-Δ12,14-Prostaglandin J2-biotin price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10141 | 15-deoxy-Δ12,14-Prostaglandin J2-biotin ≥98% | 50μg | $143 | 2026-04-30 | Buy | |
| Cayman Chemical | 10141 | 15-deoxy-Δ12,14-Prostaglandin J2-biotin ≥98% | 100μg | $268 | 2026-04-30 | Buy | |
| Cayman Chemical | 10141 | 15-deoxy-Δ12,14-Prostaglandin J2-biotin ≥98% | 500μg | $1121 | 2026-04-30 | Buy |
15-deoxy-Δ12,14-Prostaglandin J2-biotin Chemical Properties, Uses, Production
Description
15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2; Item No. 18570) is one of the cyclopentenone PGs, which have documented metabolic (peroxisome proliferator-activated receptor γ-activating), antimitotic, and antiproliferative effects.1,2,3 The activity of the compounds in this class, which includes PGs in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical (i.e., non-G protein-coupled receptor) pathways. 15-deoxy-Δ12,14-PGJ2-biotin is an affinity probe which allows 15-deoxy-Δ12,14-PGJ2 to be detected through an interaction with the biotin ligand. 15-deoxy-Δ12,14-PGJ2-biotin was designed to allow 15-deoxy-Δ12,14-PGJ2 to be detected in complexes with nuclear receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of the cyclopentenone PGs.WARNING This product is not for human or veterinary use.
References
[1] L R KRAKOFF. Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin.[J]. Clinical science and molecular medicine. Supplement, 1975, 2: 311s-313s. DOI: 10.1042/cs048311s
[2] Y KIKUCHI. Preclinical studies of antitumor prostaglandins by using human ovarian cancer cells.[J]. Cancer and Metastasis Reviews, 1994, 13 3-4: 309-315. DOI: 10.1007/bf00666101
[3] E. MUELLER. Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor γ Isoforms*[J]. The Journal of Biological Chemistry, 2002, 55 1: 41925-41930. DOI: 10.1074/jbc.m206950200
[4] ARAVINDT. REDDY. Identification and Molecular Characterization of Peroxisome Proliferator-Activated Receptor δ as a Novel Target for Covalent Modification by 15-Deoxy-Δ12,14-prostaglandin J2[J]. ACS Chemical Biology, 2018, 13 12: 3269-3278. DOI: 10.1021/acschembio.8b00584
[5] BEATRIZ DÍEZ-DACAL. Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity.[J]. Cancer research, 2011: 4161-4171. DOI: 10.1158/0008-5472.can-10-3816
15-deoxy-Δ12,14-Prostaglandin J2-biotin Preparation Products And Raw materials
Raw materials
Preparation Products
15-deoxy-Δ12,14-Prostaglandin J2-biotin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Haoran Biotechnology Co., Ltd. | -- | 470003480@QQ.COM | CHINA | 6935 | 58 |
| Shanghai Jijin Chemical Technology Co., Ltd. | -- | jijinhuaxue@sina.com | CHINA | 6589 | 58 |
| Shanghai Chaoyan Biotechnology Co., Ltd. | -- | 471161314@qq.com | CHINA | 6193 | 58 |
| Beijing Bolide Biotechnology Co., Ltd. | -- | 1985563437@qq.com | CHINA | 6507 | 58 |
| Shanghai Hao Biological Technology Co., Ltd. | -- | market@xlswkj.com | CHINA | 6772 | 58 |
| Shenzhen Xinbosheng Biological Technology Co., Ltd. | -- | service@neobioscience.com | CHINA | 6119 | 58 |
| Cayman Chemical Company | -- | cayman@caymanchem.com | United States | 6987 | 81 |
