AG-L-5968
- CAS No.
- 793035-88-8
- Chemical Name:
- AG-L-5968
- Synonyms
- CS-280;AG-L-5968;AG-L-59687;AG-L 59687;AG-L59687;α-D-Glucopyranoside, 8-[2-amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purin-9-yl]octyl;8-[2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purin-9-yl]octyl-alpha-D-glucopyranoside
- CBNumber:
- CB82603692
- Molecular Formula:
- C24H34BrN5O7S
- Molecular Weight:
- 616.53
- MDL Number:
- MFCD28101024
- MOL File:
- 793035-88-8.mol
| Product description | Number | Pack Size | Price |
| AG-L-59687 >98% | orb146105 | 100mg | $615.4 |
| AG-L-59687 >98% | orb146105 | 250mg | $1208.7 |
| AG-L-59687 >98% | orb146105 | 1g | $2395.3 |
| 2-(8-[2-AMINO-6-(4-BROMO-THIOPHEN-2-YLMETHOXY)-PURIN-9-YL]-OCTYLOXY)-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL 95.00% | INB0001399 | 1KG | $6745.2 |
| AG-L-59687 >98% | DC2063 | 100mg | $400 |
AG-L-5968 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb146105 | AG-L-59687 >98% | 793035-88-8 | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146105 | AG-L-59687 >98% | 793035-88-8 | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146105 | AG-L-59687 >98% | 793035-88-8 | 1g | $2395.3 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001399 | 2-(8-[2-AMINO-6-(4-BROMO-THIOPHEN-2-YLMETHOXY)-PURIN-9-YL]-OCTYLOXY)-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL 95.00% | 793035-88-8 | 1KG | $6745.2 | 2021-12-16 | Buy |
| DC Chemicals | DC2063 | AG-L-59687 >98% | 793035-88-8 | 100mg | $400 | 2021-12-16 | Buy |
AG-L-5968 Chemical Properties,Uses,Production
Uses
O6BTG-C8-αGlu is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor with an IC50 of 0.45 μM. At a concentration of 0.1 μM, O6BTG-C8-αGlu can completely inhibit MGMT in HeLaS3 cells. Even when applied chronically at high doses (up to 20 μM), it does not exhibit cytotoxicity. O6BTG-C8-αGlu is suitable for research on MGMT-related cancer diseases[1].
References
[1] Kaina B, et al. Inhibition of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors: comparison with nonconjugated inhibitors and effect on fotemustine and temozolomide-induced cell death. J Pharmacol Exp Ther. 2004 Nov;311(2):585-93. DOI:10.1124/jpet.104.071316
AG-L-5968 Preparation Products And Raw materials
Raw materials
Preparation Products
AG-L-5968 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2782 | 58 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9793 | 50 |
| AdooQ Bioscience CHINA | 025-58849295 18951903616; | info@adooq.cn | China | 2990 | 60 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9248 | 55 | |
| Shanghai Biopharmaleader Co., Ltd. | +86 18721201413 | sales@biopharmaleader.com | China | 1720 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 3935 | 58 |
| Cckinase, Inc. | +1 (732)236-3202 | sales@cckinase.com | United States | 2738 | 58 |
| Absin Bioscience Inc. | 021-38015121 18438616290 | lanwu@univ-bio.com | China | 24731 | 58 |
