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Amorolfine hydrochloride

Amorolfine hydrochloride structure

CAS No.: 78613-38-4

Chemical Name:: Amorolfine hydrochloride

Synonyms: AMOROLFINE HCL;2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine;Odenil;Locetar;Curanail;Amorolfine HCI;Ro 14-4767/002;Amorofen hydrochloride;Amorolfine hydrochloride;Amorolfine HCl - Bio-X ?

CBNumber:: CB8262394

Molecular Formula:: C21H36ClNO

Molecular Weight:: 353.98

MDL Number:: MFCD00903738

MOL File:: 78613-38-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:36:25

Product description	Number	Pack Size	Price
Amorolfine for system suitability European Pharmacopoeia (EP) Reference Standard	Y0001795	10 mg	$254
Amorolfine hydrochloride ≥98% (HPLC)	SML0283	10mg	$154
Amorolfine hydrochloride European Pharmacopoeia (EP) Reference Standard	Y0001794	10 mg	$231
Amorolfine hydrochloride ≥98% (HPLC)	SML0283	50mg	$403
Amorolfine Hydrochloride >98.0%(T)	A2161	1g	$214
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Amorolfine hydrochloride Properties

Boiling point	120 C
storage temp.	room temp
solubility	DMSO: ≥5mg/mL (warmed)
form	powder
color	white to beige
Major Application	pharmaceutical (small molecule)
InChI	1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16,17-,18+;
InChIKey	XZKWIPVTHGWDCF-KUZYQSSXSA-N
SMILES	Cl.CCC(C)(C)c1ccc(CC(C)CN2C[C@H](C)O[C@H](C)C2)cc1
CAS DataBase Reference	78613-38-4(CAS DataBase Reference)
FDA UNII	741YH7379H
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H302-H315-H411

Precautionary statements

P301+P312+P330

Hazard Codes

Xn,N

Risk Statements

20/21/22-36/37/38-50/53-38-22

Safety Statements

26-36-61

RIDADR

UN 3077 9 / PGIII

WGK Germany

HS Code

29411010

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Aquatic Chronic 2
Skin Irrit. 2

NFPA 704

	0
2		0

Amorolfine hydrochloride price More Price(96)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0001795	Amorolfine for system suitability European Pharmacopoeia (EP) Reference Standard	78613-38-4	10 mg	$254	2026-04-30	Buy
Sigma-Aldrich	SML0283	Amorolfine hydrochloride ≥98% (HPLC)	78613-38-4	10mg	$154	2026-04-30	Buy
Sigma-Aldrich	Y0001794	Amorolfine hydrochloride European Pharmacopoeia (EP) Reference Standard	78613-38-4	10 mg	$231	2026-04-30	Buy
Sigma-Aldrich	SML0283	Amorolfine hydrochloride ≥98% (HPLC)	78613-38-4	50mg	$403	2026-04-30	Buy
TCI Chemical	A2161	Amorolfine Hydrochloride >98.0%(T)	78613-38-4	1g	$214	2026-04-30	Buy

Product number	Packaging	Price	Buy
Y0001795	10 mg	$254	Buy
SML0283	10mg	$154	Buy
Y0001794	10 mg	$231	Buy
SML0283	50mg	$403	Buy
A2161	1g	$214	Buy

Amorolfine hydrochloride Chemical Properties,Uses,Production

Description

Amorolfine hydrochloride is the first morpholine antifungal agent useful in the topical treatment of onychomycosis. Mechanistically, it appears to inhibit two stages of the ergosterol biosynthetic pathway, which is necessary for fungal cell viability. Active against a broad spectrum of fungi, amorolfiie hydrochloride is particularly effective against yeasts such as Histoplasma capsulatum, dermatophytes and dematiaceous fungi.

Chemical Properties

Liquid

Originator

Roche (Switzerland)

Uses

Amorolfine hydrochloride has been used as an antifungal agent.

Uses

antihypertensive

Definition

ChEBI: A hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine. An inhibitor of the action of squalene monooxygenase, Delta14 reductase and D7-D8 isomerase and an antifungal ag nt, it is used for the topical treatment of fungal nail and skin infections.

brand name

Loceryl (Hoffmann-LaRoche).

Biochem/physiol Actions

Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.

Amorolfine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Amorolfine hydrochloride Suppliers

Global( 381)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850	info@fortunachem.com	China	5983	58
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	sales@aochuangchem.com	China	9333	58
Firsky International Trade (Wuhan) Co., Ltd	+8615387054039	admin@firsky-cn.com	China	427	58
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1085	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Cangzhou Wanyou New Material Technology Co.,Ltd	18631714998	sales@czwytech.com	CHINA	904	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Wuhan Fortuna Chemical Co., Ltd	58
Henan Aochuang Chemical Co.,Ltd.	58
Firsky International Trade (Wuhan) Co., Ltd	58
Hebei Xinsheng New Material Technology Co., LTD.	58
Anhui Ruihan Technology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Cangzhou Wanyou New Material Technology Co.,Ltd	58

View Lastest Price from Amorolfine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-09	Amorolfine hydrochloride 78613-38-4		1kg	99%min HPLC	100kg	WUHAN FORTUNA CHEMICAL CO., LTD
2026-05-15	Amorolfine hydrochloride 78613-38-4	$4762.00	500g/Bag	98%	100KG	Baoji Guokang Healthchem Co., Ltd.
2026-05-11	Amorolfine hydrochloride 78613-38-4	$55.00-82.00		99.94%	10g	TargetMol Chemicals Inc.

Amorolfine hydrochloride
78613-38-4
$0.00
99%min HPLC
WUHAN FORTUNA CHEMICAL CO., LTD

Amorolfine hydrochloride
78613-38-4
$4762.00
98%
Baoji Guokang Healthchem Co., Ltd.

Amorolfine hydrochloride
78613-38-4
$55.00-82.00
99.94%
TargetMol Chemicals Inc.

Amorolfine hydrochloride Spectrum

Amorolfine hydrochloride(78613-38-4)¹HNMR

78613-38-4(Amorolfine hydrochloride)Related Search:

Moroxydine hydrochloride Moroxydine 1-AdaMantanethylaMine Isopropylhydrazine Hydrochloride Amorolfine

Amorolfine hydrochloride Topotecan hydrochloride Tridemorph Dimethomorph Hydroxylamine hydrochloride

Tramadol hydrochloride cis-2,6-Dimethylmorpholine Dimethylmorpholine Sibutramine hydrochloride N-[2-(acetyloxy)propyl]-N-[3-[4-(1,1-diMethylpropyl)phenyl]-2-Methylpropyl]-forMaMide

Amorolfine Impurity 11 Amorolfine Impurity 6 4-[3-[4-(1,1-diMethylpropyl)-phenyl]-2-Methylpropyl]-2,6-diMethylMorpholine 4-oxide

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Amorolfine HCI Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, (2R,6S)-rel- Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, cis- Ro 14-4767/002 (+/-)-cis-2,6-Dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine hydrochloride Amorolfine hydrochloride (2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, hydrochloride (1:1) (2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride Amorolfine hydrochloride, >=99% AMOROLFIN; CURANAIL; LOCERYL; LOCETAR; ODENIL Curanail Locetar Odenil 2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride Amorolfine for system suitability (2R,6S)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride Amorolfine Hydrochloride > Amorolfine for system suitability CRS Amorolfine hydrochloride CRS cis-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride (2R,6S)-rel-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride Amorolfine hydrochloride USP/EP/BP Amorolfine HCl (Ro 14-4767/002) Amorolfine HydrochlorideQ: What is Amorolfine Hydrochloride Q: What is the CAS Number of Amorolfine Hydrochloride Q: What is the storage condition of Amorolfine Hydrochloride Q: What are the applications of Amorolfine Hydrochloride 13C6]-Amorolfine hydrochloride (2S,6R)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride Amorofen hydrochloride rel-(2R,6S)-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride (Amorolfine Impurity) Amorolfine hydrochloride, 10 mM in DMSO Amorolfine HCl - Bio-X ? Amorolfine hydrochloride 99% Amorolfine (Ro 14-4767/002) hydrochloride Amorolfine HClEP/CP78613-38-4CEP 2017-091 4-(3-paratertpentylphenyl-2-methylpropyl)-cis-2,6-dimethylmorpholinehydrochloride 2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine AMOROLFINE HCL 78613-38-4 78163-38-4 C21H35ONHCl HYTRIN Antifungal (Topical) Antifungals for Research and Experimental Use Biochemistry 78613-38-4