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3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid structure

CAS No.: 1334286-77-9

Chemical Name:: 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

Synonyms: PEG3-acid;HO-2-COOH;OH-PEG2-COOH;HO-PEG3-acid;Hydroxy-PEG2-acid;Hydroxy-PEG3-acid;HO-(CH2CH2O)2-CH2CH2COOH;Hydroxy-PEG2-propionic acid;Hydroxy-PEG2-acid sodium salt;3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

CBNumber:: CB82679367

Molecular Formula:: C7H14O5

Molecular Weight:: 178.18

MDL Number:: MFCD20646030

MOL File:: 1334286-77-9.mol

Last updated:2025-09-12 18:45:48

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3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid Properties

Boiling point	350.0±27.0 °C(Predicted)
Density	1.196±0.06 g/cm3(Predicted)
storage temp.	Storage temp. 2-8°C
solubility	Soluble in Water, DMSO, DMF
form	A liquid
pka	4.27±0.10(Predicted)
color	Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05,GHS07
Signal word	Danger
Hazard statements	H302-H315-H318-H335
Precautionary statements	P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501
HS Code	2942000090

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	H949673	3-[2-(2-Hydroxyethoxy)ethoxy]propanoicacid	1334286-77-9	250mg	$235	2021-12-16	Buy
TRC	H949673	3-[2-(2-Hydroxyethoxy)ethoxy]propanoicacid	1334286-77-9	1g	$515	2021-12-16	Buy
BroadPharm	BP-23136	Hydroxy-PEG2-acidsodiumsalt 95%	1334286-77-9	1g	$320	2021-12-16	Buy
American Custom Chemicals Corporation	POL0002456	HYDROXY-PEG2-ACID 95.00%	1334286-77-9	1G	$401.1	2021-12-16	Buy
Acrotein	B-0596	HO-PEG2-CH2CH2COOH 97%	1334286-77-9	0.5g	$146.66	2021-12-16	Buy

Product number	Packaging	Price	Buy
H949673	250mg	$235	Buy
H949673	1g	$515	Buy
BP-23136	1g	$320	Buy
POL0002456	1G	$401.1	Buy
B-0596	0.5g	$146.66	Buy

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid Chemical Properties,Uses,Production

Description

Hydroxy-PEG2-acid sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Uses

Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid Suppliers

Global( 78)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	9029	58
9i LLC	+18039569191	MWan@NiNeiLab.com	United States	418	58
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29800	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5744	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32432	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
XIAMEN SINOPEG BIOTECH CO., LTD.	+86-0592-7761068 +8617350879715	changaiwei@sinopeg.com	China	411	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20405	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
9i LLC	58
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Borenpharm Co., Ltd	58
XIAMEN SINOPEG BIOTECH CO., LTD.	58
Alfa Chemistry	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58

View Lastest Price from 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-12	3-(2-(2-hydroxyethoxy)ethoxy)propanoic acid 1334286-77-9	US $0.00-0.00 / g	1g	98%	1g/bottle, 10g/bottle, 100g/bottle	XIAMEN SINOPEG BIOTECH CO., LTD.
2025-08-21	Hydroxy-PEG2-acid 1334286-77-9	US $0.00 / mg			10g	TargetMol Chemicals Inc.
2025-08-06	Hydroxy-PEG2-acid 1334286-77-9	US $2.00-6.00 / kg	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

3-(2-(2-hydroxyethoxy)ethoxy)propanoic acid
1334286-77-9
US $0.00-0.00 / g
98%
XIAMEN SINOPEG BIOTECH CO., LTD.

Hydroxy-PEG2-acid
1334286-77-9
US $0.00 / mg
TargetMol Chemicals Inc.

Hydroxy-PEG2-acid
1334286-77-9
US $2.00-6.00 / kg
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid Spectrum

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid(1334286-77-9)¹HNMR

1334286-77-9(3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid)Related Search:

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Hydroxy-PEG2-propionic acid 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid PEG3-acid Hydroxy-PEG3-acid Hydroxy-PEG2-acid HO-PEG3-acid α,ω-hydroxy--propionic acid diethylene glycol OH-PEG2-COOH HO-2-COOH Propanoic acid, 3-[2-(2-hydroxyethoxy)ethoxy]- HO-(CH2CH2O)2-CH2CH2COOH Hydroxy-PEG2-acid sodium salt HO-PEG2-CH2CH2COOH/Propanoic acid, 3-[2-(2-hydroxyethoxy)ethoxy]- 1334286-77-9 peg